💡New study alert!
Want to know if the complex 'cocktail' of chemicals in our buildings and products are exposing us to extra doses of hormone mimics?
Read more here ~
authors.elsevier.com/a/1gOuWAOM9zio0
THREAD 🧵(1/7)
Want to know if the complex 'cocktail' of chemicals in our buildings and products are exposing us to extra doses of hormone mimics?
Read more here ~
authors.elsevier.com/a/1gOuWAOM9zio0
THREAD 🧵(1/7)
🧵(2/7)
Office workers wore silicone wristbands in their office buildings for 4 workdays as a way to collect the chemical 'cocktail' they were each exposed to.
The avg person was exposed to at least 800 (!) diff chemical signatures. A large fraction of those chems were unknown.
Office workers wore silicone wristbands in their office buildings for 4 workdays as a way to collect the chemical 'cocktail' they were each exposed to.
The avg person was exposed to at least 800 (!) diff chemical signatures. A large fraction of those chems were unknown.
🧵(3/7)
We then took each sample's entire chemical mixture and exposed human cells in the lab to it – to see how human cells responded to all the chemicals at once
The result?
EVERY sample disrupted sex hormones or thyroid hormone
Higher chemicals➡️higher hormonal bioactivity
We then took each sample's entire chemical mixture and exposed human cells in the lab to it – to see how human cells responded to all the chemicals at once
The result?
EVERY sample disrupted sex hormones or thyroid hormone
Higher chemicals➡️higher hormonal bioactivity
🧵(4/7)
So:
1⃣We're regularly exposed to 100s of known and UNKNOWN chemicals
2⃣Many of the chems mimic or block hormones that are critical for reproduction & metabolism – and their effects pile on top of each other
3⃣Sources include cosmetics, fragrance, furniture, pesticide
So:
1⃣We're regularly exposed to 100s of known and UNKNOWN chemicals
2⃣Many of the chems mimic or block hormones that are critical for reproduction & metabolism – and their effects pile on top of each other
3⃣Sources include cosmetics, fragrance, furniture, pesticide
🧵(5/7)
4⃣Women were exposed to mixtures that had MORE chemicals and HIGHER interference with estrogen & androgen hormone receptors
A big reason for this gender disparity is likely the difference in use of cosmetics, which often contain hormone-disrupting chemicals 💄💅
4⃣Women were exposed to mixtures that had MORE chemicals and HIGHER interference with estrogen & androgen hormone receptors
A big reason for this gender disparity is likely the difference in use of cosmetics, which often contain hormone-disrupting chemicals 💄💅
🧵(6/7)
The #scientific challenge:
Traditional ways to research chemicals only one at a time do not realistically portray how we're exposed to complex chem mixtures
Our approach:
🧪Wristband samplers of REAL WORLD exposure
🔎1,000+ known AND unknown chems
🔎Hormone cell assays
The #scientific challenge:
Traditional ways to research chemicals only one at a time do not realistically portray how we're exposed to complex chem mixtures
Our approach:
🧪Wristband samplers of REAL WORLD exposure
🔎1,000+ known AND unknown chems
🔎Hormone cell assays
🧵(7/7)
With truly amazing collaborators, including @nickherkert @j_g_allen & many twitterless
@HarvardChanSPH @HarvardCatalyst @hsphniehsctr @HarvardChanERC
@DukeSuperfund @DukeEnvironment @UMassAmherst
Free access to study for 50 days with this link:
authors.elsevier.com/a/1gOuWAOM9zio0
With truly amazing collaborators, including @nickherkert @j_g_allen & many twitterless
@HarvardChanSPH @HarvardCatalyst @hsphniehsctr @HarvardChanERC
@DukeSuperfund @DukeEnvironment @UMassAmherst
Free access to study for 50 days with this link:
authors.elsevier.com/a/1gOuWAOM9zio0
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