Exciting news!
Novavax is working on an Omicron XBB specific vaccine with data expected to be presented at this month's FDA VRBPAC meeting.
Unlike Pfizer and Moderna #Novavax hasn’t yet updated its vaccine to specifically target more recently circulating strains of the virus.
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“Up through BA.5, our immune responses had held steady,” said Filip Dubovsky, Novavax’s chief medical officer.
“I can tell you right now that this #xbbvariant XBB, XBB.1, it looks different to us.” 2/ #kraken#XBB#XBB15 $NVAX barrons.com/articles/novav…
Dubovsky said that Novavax has begun making the so-called viral seed needed to begin the manufacturing process for an updated version of its vaccine that would target XBB.1.1.5 #Novavax will present data on the XBB family of viruses at an advisory committee hearing this month
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It's good that #Novavax is developing an #XBB specific vaccine. However, it also sounds a warning.
If Novavax is saying that the immune response to the #XBBvariant looks different, now is not the time for complacency. Please keep testing, masking & meet in well ventilated spaces
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Ayesha Verrall on the most recent changes to Covid settings:
“I advocated for this package to be adopted.”
There was an obvious reluctance to step up protections in the future, because the government has promised "certainty" that events will go ahead. 1/
The certainty of summer festivals and events appears to be more important than preventing infection or allowing medically vulnerable people to safely access public transport or to participate in society.
Ableism, we see you.
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Q: Would there be restrictions again?
A: Gov takes into account economic/social impacts & population immunity.
That’s circular logic. Allow Covid to infect everyone. When new variants arrive gov claims people have natural immunity so no need to protect people from (re)infection
When asked if COVID was going to be with us forever, like cancer and heart disease, and be one of our biggest killers @DrAndrewOld said we would be “very unlikely” to eliminate it from the world but hopefully it would be manageable with an annual vaccine like influenza. 1/
Dr Old says the jury is out on where cases will plateau but the expectation is that there will be a lull and then future waves, with the possibility of a wave over summer.
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Although the current wave is mostly over, MOH modelling suggests that the dropping of protections could result in an uptick of 10-20% of cases in the next few weeks before settling down to slightly higher than current levels (+2-4%).
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BA.2.75.2 (subvariant of #Centaurus) is one to watch. Early data suggests Omicron BA.2.75.2 exhibits more extreme antibody escape than any variant to date. It’s too early to know whether this will result in a wave
Further explanation here. Neutralizing antibody levels for vaccinated & (overwhelmingly) infected serum is >5-fold lower than BA.5 & nearly 4-fold lower than BA.4.6