Them: The COVID-19 vaccines don’t work. The majority of hospitalizations/deaths/infections are fully vaccinated.

Me: Base Rate Fallacy would like a word with you.
Let’s try something. Most people get this question wrong. Can you solve it? A town has only two colours of car: 85% are blue and 15% are green. A person witnesses a hit-and-run and says they saw a green car. If witnesses identify the colour of cars correctly 80% of the time, what
are the chances the car is actually green? You might have said 80%. A lot of people do. The correct answer is 41%. The reason so many struggle with this question is due to the Base Rate Fallacy. Our brains tend to ignore statistical information (aka base rates) and focus on
specific information related to people and events. We're distracted by the witness, and forget how rare green cars are in the town. This problem uses Bayes Theorem. If we randomly selected 100 cars, 85 would be blue and 15 would be green. If a witness correctly identifies green
cars 80% of the time they will identify 12 green cars correctly (80% × 15 green cars). The witness misidentifies 20% then they will misidentify 17 cars as green when they are actually blue (20% x 85 blue cars). In this case. 29 cars would be identified as green (12 + 17) but only
12 actually are green. Therefore there is only a 41% chance that the car the witness identified is actually green (12/29 = 0.41). THE BASE RATE FALLACY CAN SHOW UP IN LOTS OF PLACES, INCLUDING IN OUR UNDERSTANDING OF COVID-19 DEATHS OR HOSPITALIZATIONS. For example, last
summer, Iceland saw a rise in COVID-19 cases, and most cases were among those fully vaccinated. BUT vaccines STILL WORK. MORE CASES AMONG FULLY VACCINATED PEOPLE IN PLACES WITH HIGH VACCINATION RATES IS NORMAL: But the rate (infections per person) of COVID-19 in Iceland is HIGHER
in unvaccinated people than those vaccinated, meaning it's way better to be vaccinated. Almost everyone eligible for vaccines in Iceland is fully vaccinated. So when COVID cases do happen in Iceland, most of them happen in vaccinated people because they are the vast majority of
the population. Iceland and other countries with high vaccination rates are likely to see more cases among the vaccinated, even though the rate of infection is significantly HIGHER in unvaccinated people. Because there just aren't that many unvaccinated people for COVID-19 to
infect. You can find all of this here: scienceupfirst.com/project/the-ba… and credit for the extremely informative graphic above goes to @/MarcRummy.
Please also read this thread in its ENTIRETY ALL on vaccines and debunking misinformation:
So, when a headline or a random Twitter user says "vaccinated people now make up a majority of deaths" it is innumerate fear-mongering and misinformation when it comes down to it that will make some misinterpret that as "vaccines are only 50% effective” or worse misconceptions.
TLDR. The more people you vaccinate, the higher their share of hospitalizations, but the *TOTAL* number in the hospital is a FRACTION of what it would otherwise be. The FEWER people fully vaccinated, a smaller share of hospitalizations will be fully vaccinated as well, BUT this
isn’t good. Why? Overall there would be A LOT more people in the hospital because far more of the population is unprotected. In other words, don't focus on whether fully vaccinated individuals make up a % of hospitalizations, focus on the RATES those individuals whether
vaccinated or unvaccinated are ending up in the hospital. SPOILER ALERT: Rates are A LOT higher for unvaccinated. An increasing ratio of hospitalized vaccinated individuals however is an inevitable result of increasing vaccination rates. It is a marker of success, NOT failure.

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More from @sailorrooscout

Jan 18
This is HUGE news! Moderna’s Respiratory Syncytial Virus (RSV) vaccine candidate (mRNA-1345) demonstrated stellar efficacy (83.7% against SEVERE lower respiratory illness). Moderna plans to submit for regulatory approval. If approved, this will be THE FIRST RSV vaccine!
Vaccine efficacy of 83.7% was observed against severe medically attended lower respiratory tract illness due to RSV in older adults. The ConquerRSV trial is a randomized, double-blind, placebo-controlled study of approximately 37,000 adults 60 years or older in 22 countries,
including the US (NCT05127434). The primary efficacy endpoints were based on two definitions of RSV-LRTD defined as either two or more symptoms, or three or more symptoms of disease. The interim analysis was based on 64 cases of RSV-LRTD with two or more symptoms, of which 55
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Jan 15
Science Rules! 🥼🧬🧫🦠🔬💉🥽
I hope everyone is having a good weekend! Science threads will resume on Monday. In the meantime, be sure to check out my most recent threads on PEER-REVIEWED COVID bivalent booster data, all about XBB/XBB.1/XBB1.5, how vaccines work, and other helpful threads. Thank you!
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Jan 11
Vaccines save lives.

That’s it. That’s the tweet.
Okay, so maybe that’s NOT the only tweet. Just a heads up. “Died Suddenly” is trending so allow me to kindly save you the trouble of looking it up. It’s anti-vax propaganda. Plain and simple. That’s it. Do NOT waste your time. Instead, consider reading:
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Jan 7
Just a marten in a lab coat.
🧬🧫🦠🔬💉🥼🥽 Image
I hope everyone is having a good weekend! Science threads will resume on Monday. In the meantime, be sure to check out my most recent threads on PEER-REVIEWED COVID bivalent booster data, all about XBB/XBB.1/XBB1.5, how vaccines work, and other helpful threads. Thank you!
Read 4 tweets
Jan 5
Can’t believe this needs to be said but here we are.

The vaccines for COVID-19 CANNOT and DO NOT cause COVID. None of the current COVID vaccines contain nor utilize live SARS-CoV-2 virus, so you cannot contract COVID-19 from the vaccines. It is biologically impossible.
The mRNA vaccines instruct your cells to reproduce a protein that is part of the SARS-CoV-2 virus, which helps your body recognize and fight the virus, if it comes along. Note. The spike protein IS NOT the virus. It’s a protein. It can’t do anything on its own without other
viral components that make up the virus itself. Again, the COVID-19 vaccines do not contain the SARS-Co-2 virus, so you cannot get COVID-19 from the vaccine. The spike protein that helps your immune system recognize and fight the virus DOES NOT cause infection of any sort. ImageImageImage
Read 14 tweets
Jan 1
Happy New Year!

Just a friendly reminder. Despite what you might hear, there has yet to be a variant that isn’t susceptible to the vaccines.

Let’s stop the misinformation and look at the data, shall we? Yes, this includes XBB/XBB.1/XBB.1.5. Let’s talk about that.🧵⬇️
Why are variants unlikely to FULLY evade vaccine-induced immunity?
•Vaccines are POLYCLONAL
•CD8+ T-cells covering 52 epitopes across the spike protein
•CD4+ T-cells covering 23 epitopes across the spike protein
science.org/doi/10.1126/sc…
I am seeing a ton of misinformation circulating so I thought it might be a good idea to make a thread on this. When you see “evading vaccines” PLEASE KEEP IN MIND this is usually in regards to neutralizing antibodies ONLY. NOT PROTECTION AGAINST SEVERE DISEASE.
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