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Jan 25 • 19 tweets • 11 min read
1. You want freedom from COVID-19?

(1) Three community measures ended SARS 2003, H5N1 2009:
N95+eye protection,
test & trace,
isolation of the infected;

(2) Two at the international level:
travel surveillance & quarantine (never used 2020).

It’s a political science problem. 👍
2. It doesn't matter if you 'believe in' human immune system (HIS) damage from SARS-CoV-2. It just IS.

Here a poetic Reality Check Marker thread. Read all; my shortcut for HIS question.

Political scientists and lawyers will need to learn to read science.
3. It doesn't matter if you 'believe in' constitutional or human rights law. It just IS.

I translate because even highly educated people with a strong STEM or humanities background don't easily make the connection.

The hallmark of a true systems problem.
4. Want a good life without the fastest-evolving airborne pathogen in human history, yourself or for your children?

Do the political work to eradicate SARS-CoV-2.

The medical part is going relatively well. Broken beyond repair is the political apparatus.
5. The medical part is going relatively well (don't tell the HCW/MD who are heartbroken to see the healthcare system in flames #Medizinbrennt) because at least they're heartbroken.

The political system is burning unseen, far more insidious. #Politikbrennt
6. Make an effort to read these papers and bibliography. It may be your best chance.

Why shared by unpaid systems scholars like me and other scientist-activists?

Why are your public health authorities or media silent?

Maybe you can answer this? I can't.
7. Good paper, part II. Keep an eye on what China is doing with Covid cases, not what western governments or 'experts' who proved complacent for III years hope it is. The answer is almost certainly not nothing.

Happy New Year's Reading everyone, 新年快乐!
mdpi.com/1422-0067/24/3…
8. I mentioned previously that the lessons of SARS 2003 were distilled into reports like these. Be sure to read them.

This is next week's homework assignment. Start with the above papers, so you know why any of this even matters.
9. Call it any name that helps common people understand: SARS is (1) airborne and (2) damages immune and vascular system. Scientific certainty will take years.

Never wait for scientific certainty to end the public health threat. That's the essence of the precautionary principle.
10. I think we've said all this before. Sorry for the repetition those of you who read this (so often). Sorry for not reaching those who don't.

Good luck us!
11. People say eradication is impossible. Yet they know the original COVID-19 (Wuhan wildtype) is extinct.

Only one of these two statements can be true!

Why do most opt into reinfection with new COVID-19 strains (VoC), out of sheer intellectual laziness?
12. Why is SARS a political science problem?

SARS-CoV-2 helps us learn the governance skills for our near and long-run future. (Find bodyguard manipulation illustrated here to lighten the mood.) 🥰 Yet science isn't heard.

Who is? Always political power.
13. As an aside, the silence of scientists who SHOULD know - if they cared enough to read - has allowed unspeakable volumes of anti-science views to flourish. I don't blame science-illiterate people; they only get disinformation if there is no information.
* Consider following @fitterhappierAJ and @1goodtern if you don't yet -- for your own protection and mental sanity. At least such unwarranted controversy has the benefit of introducing more people to the questions that matter.
@fitterhappierAJ @1goodtern 14. Dr Leonardi wrote an overview to introduce the SAg motif in SARS-CoV-2; from a systems perspective I add that SARS will teach us.

Call it SARS-acquired governance skills (SAGS).

Happy learning everyone,
pnas.org/doi/10.1073/pn…
mdpi.com/2076-0817/11/4…
@fitterhappierAJ @1goodtern 15. Can fungi and bacteria - not just poxviruses (for now mpox) and other RNA viruses reproducing in the cytoplasm - borrow SARS-CoV-2's immune evasive superpowers (Orf8) via genetic recombination?

I don't know! A scientific hypothesis to keep in mind beside the #LeonardiEffect.
@fitterhappierAJ @1goodtern * Being very scientific, we quote our sources. (The last of us, HBO, above; haven't watched, via @kenekambili)
16. Yes, that's the question on all our minds. Don't give SARS second chances; or not even first ones if you can help it. Be well, Mel and everyone out there!
17. I forgot to link the Columbia (?) scholar who gave a talk on how to hide a pandemic and is now writing the book; feel free to share.

Here's how.

For unparalleled density and SARS expertise, RealCheckMarker threads, but there are enough other sources.

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More from @_ppmv

Paul Maidowski Profile picture
Jan 26
Pinning this 🙏 Simple argument, as COVID-cyberpunk as it gets. Add a shade of climate and you're good to fly: Reverse the global trend of supervillainy that SARS will usher into unless we stop it. - We CAN, by simple effective policy. Just as in all the WHO/UN superhero stories. ImageImageImage
1. Did the superhero stories forget to mention political scientists? - The simple effective policy is

N95+eye protection
test & trace
isolation of the infected
international travel surveillance & quarantine

They involve plane science, no rocket science.
2. We also forgot those who will end the pandemic: lawyers!

Not scholars or practitioners of international law alone -- but it follows from the structure of our systemic problems that no solution can work without them.
Read 21 tweets
Paul Maidowski Profile picture
Jan 26
1. The legal phase of the pandemic started.

This letter criticizes the end of SARS (‘Corona’/‘Covid’) protections in schools. What @LEK_NRW can improve: every child is at risk. Everyone is vulnerable to SARS-CoV-2 infections. Vaccines provide statistically irrelevant protection.
@LEK_NRW 2. Children once or repeatedly infected with SARS-CoV-2 may be harmed for life; school and kita are key to SARS-CoV-2 transmission and evolution.

Fantini et al. apply 40 years of HIV research to SARS. Parents & students, you need to read for yourselves. mdpi.com/1422-0067/24/3…
@LEK_NRW 3. @JessicaLexicus summarized what German Health Minister Dr. Lauterbach's admission meant last week; never mind the rowback. jessicawildfire.substack.com/p/the-gig-is-u…
Read 8 tweets
Paul Maidowski Profile picture
Jan 25
Astute observation. Part of our problem is most western folk & elites have limited international working & policy delivery experience especially in the global south.

Many may struggle to imagine public health information being suppressed in their own nations; hard to blame them.
Fortunately everyone aware of climate dynamics, or trained in development economics, should be free from such troubles.
We sometimes call our socially constructed lack of imagination ‘the Unthinkable’ (@GhoshAmitav). One of the reasons he argued middle-class westerners and academics may be less prepared for the future than far poorer people in the global south, even Indian farmers.
Read 5 tweets
Paul Maidowski Profile picture
Jan 24
1. Read this paper.

HIV-1 is the best researched virus in biology. SARS-CoV-2 stands on the giant shoulders of 40 years of research, winning us decades in a tight race. - Please take it seriously; never fear language over biology. I invited HIV/SARS scientists to collaborate. 👍
2. Happy to share the entire paper in screenshots if it helps anyone, but I think not needed - it's open access. mdpi.com/1422-0067/24/3…

Recall that's only medicine/life sciences; small part of the whole picture. I previously shared the governance angle:
3. These questions strike the heart of both social and natural science perspectives in this pandemic. Fascinating to see things develop so fast, well done everyone!
Read 6 tweets
Paul Maidowski Profile picture
Jan 24
A legal puzzle: @RealCheckMarker warned that states may try muzzling science by cutting funding and genetic surveillance (PCR tests and sequencing). Lack of data will force WHO to declare the pandemic over.

Yet SARS is a notifiable event. The PHEIC would be back within 24 hours. ImageImage
Are they defunding science? Data suggests so.

Look at the drop in sequencing volume in most countries over the past four weeks. It is dangerous and completely unacceptable. We are blinding ourselves.

Journalists, it’s your job to call this out, not mine. Image
Silver Check Mark if your quantitative reasoning skills are sharp enough to tell how many states test BELOW the volume needed for variant determination at 5% prevalence.

Gold if you often check the ECDC links and share in public 🥰 ecdc.europa.eu/en/covid-19
…id19-country-overviews.ecdc.europa.eu/variants_of_co…
Read 19 tweets
Paul Maidowski Profile picture
Jan 24
1. Why learning to think?

If you didn’t know, you underestimated the policy challenge of COVID. ImageImage
2. Why learn to think and face reality?

Expect high-order nonlinear feedbacks from damaging the human immunosphere for years to come even IF we end the pandemic soon.
3. Why learn to think fast?

Unsustainable means by definition it cannot last. Change is the only certainty.
Read 8 tweets

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