Paul Maidowski Profile picture
language, systems, climate policy. Fletcher/Fulbright d|e|f|i|中. Go(围棋) @ppmv.bsky.social https://t.co/Mqo4ELPYqB https://t.co/hiHp7ti0dm
ARP Profile picture Délcio Neitzke Profile picture Jenny Richardson Profile picture cuora.spp Profile picture julais Profile picture 9 subscribed
Jan 14 4 tweets 2 min read
Excellent paper @ejustin46 found. Only one major problem Granted, few if any papers so far explain the Orf8 gene in beta-CoVs but never mind, that’s why you have twitter
Jan 9 6 tweets 3 min read
SARS-CoV should be compared to HIV. They are the two best researched viruses in history. "Compare and contrast X and Y" is about the most common essay question in middle school language classes worldwide; people who want to prevent this have ill (no dad joke intended) intentions. As AJ says, different opinions are perfectly valid here as long as people read carefully. It will get very complex. This is why as political scientist, to me learning from the policy & social parallels to the HIV/AIDS pandemic is paramount. Compare away,
Jan 7 5 tweets 2 min read
Don’t use Covid/LC. The real term in the literature since 2003 has been SARS survivors. It’s a SARS virus, so this require no rocket scientist, a Google search suffices. Wild how you minimize your own condition out of ignorance, friends. Worst social movement strategy I’ve seen. Why bad? If you define LongCovid narrowly as the most extreme forms of ME/CFS or whatever, you minimize the 200+ symptoms recognized by WHO, marginalize all the hundreds of millions living with chronic infection, and slow public recognition, R&D & prevention. All around failing.
Jan 4 6 tweets 2 min read
Life expectancy of children "Living with Covid" at a rate of 1 to 3 infections per year, de facto current policy in all states worldwide Country not specified, so this is the global average. - For once twitter's limited questionnaire format fits like a chin to the fist 🙌
Jan 3 32 tweets 17 min read
1. 'Live with Covid' is terrible advice. Old examples of what's possible: Arthur Schlossmann halved infant mortality from >50% by introducing hygiene in Dresden. Pasteurization of milk ended constant bovine coronavirus outbreaks, doubling lifespans after 1889. We can do the same.
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2. I shared hundreds of scientific references - and as political scientist I only explain molecular and epidemiological dynamics because without scientific foundation, you will get no effective policy. But no one wrote a real, comprehensive narrative yet.
Jan 2 7 tweets 3 min read
Happy year 5 of the SARS pandemic everyone. My annual reminder, any think tanks, analysts or -imagine!- policymakers out there who are actually serious about defending democracy? If you continue 'Living with Covid,' since every infection damages people's brains and CSF, no chance Political scientist here. Other systems of governance may have better chances; they ask less critical thought to keep democratic institutions running of the average citizen. Very exciting research questions going forward.

Well done everyone who stayed based in reality. 🤷‍♂️🏆
Jan 1 7 tweets 3 min read
— "Dad, what's the most common Long Covid symptom?"

— "Don't know and don't care, son"

karger.com/crn/article-pd…
Image "I don't care if you follow us for further apathetic dad jokes and tasteful scicomm" 🤣🤣
Dec 22, 2023 10 tweets 5 min read
1. SARS-CoV and prion disease (PrD): Will do a thread just as soon as I can scrape my chin off the floor. Dr. Laura Manuelidis starts high and goes hard sentence for sentence tandfonline.com/doi/full/10.10…

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2. Ends on a high note
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Dec 18, 2023 17 tweets 10 min read
1. SARS-CoV and HIV share chronic systemic immune activation. Read this as if your life depends on it. Thank me later. Make sure you understand disease progression en detail. How much do you recognize in SARS-CoV?

Happy year 5 vs. year 42 of the pandemic, nature.com/articles/s4157…
Image 2. Not joking about the "teach a man to hunt, fish and cook and you can get great dinner every night unless global deoxygenation and acidification get all the fish in which case you'll have other problems" thing. Here your search function, go wild and read scholar.google.com/scholar?as_ylo…
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Dec 4, 2023 93 tweets 46 min read
1. SARS-CoV challenges us. Two examples stand out: Arthur Schlossmann halved infant mortality from >50% by introducing hygiene in Dresden. Pasteurization, after Louis Pasteur, ended constant bovine coronavirus outbreaks, doubling the human lifespan after 1889. We can do the same. Image 2. A long thread with 200+ scientific references, as multiple others, cover this, so if you're the type of reader who can extract highly specific information from dense articles, go for it. It's not didactically organized though; I'll rewrite over time.
Dec 1, 2023 7 tweets 2 min read
1. Bacteriophage-like: "Our results strongly suggest interactions with bacteria in intestinal microbiota. SARS-CoV-2 can enter the cells of bacteria that are part of the normal human gut microflora and synthesize both RNA and viral peptides. Important etc. f1000research.com/articles/11-292 2. Interview with Carlo Brogna, author of a widely read bacteriophage paper. Not sure I'm buying all of that, but that was an early, decent warning.
Nov 10, 2023 16 tweets 5 min read
Funny. If you all don’t see what contributions social scientists make, try to find any better source than my feed & the hundreds of scientific studies I shared for free to explain how we could end the pandemic. Some million to billion lives depend on it, so go ahead, try & share. Image May as well do a thread of threads because post-Melon Twitter is terrible for scicomm purposes, a labyrinth of information that traps the nest minds. We only use it because it’s the best tool we have. 200+ scientific studies and master narrative
Nov 8, 2023 4 tweets 2 min read
Climate and political scientists like me have been warning since 2018 global warming will accelerate. Dr. @Michaelemann built a personal brand on policing such warnings without understanding the eider literature. Recognize how dangerous such ego trips are. nature.com/articles/d4158… Eisdom of the day: twitter is not eorth correcting autocorrect. Thanks for good humor and be well everyone. Also don’t accept half-knowledge and bullies like Dr. Mann, since they can implode any basis for evidence-based policy.
Oct 31, 2023 8 tweets 3 min read
Morning all, next pandemic started &/or same old, depending on your premises & whether you view life as an ongoing process we are privileged to experience or a succession of disparate events hitting your brainstem like an axe. This by John the mathematician from mid-2022
Image That’s a climate meme by @leftywright44; as we keep warning, public health professionals can learn from the last few decades of climate work Image
Oct 20, 2023 10 tweets 5 min read
SARS is THE textbook example for (1) failure of systems thinking; (2) western expert hubris; (3) lack of state capacity; (4) STUNNING failure of journalism; (5) plain old racism & orientalism. Western policymakers huffed herd immunity hopium, which is impossible for SARS. 👋🏿 👋🤗 2. All was obvious in January 2020, people just didn’t pay attention. Pretty sure racism is the root cause here, “docile Asian populations wear masks but we western rebels won’t” or whatever base instincts told them. 😂 enjoy your public humbling, everyone
Oct 12, 2023 4 tweets 2 min read
This thread 👇 brought to you by the realization that the clinical study on SARS survivors 18 years after 1 (!) infection has not even a single citation. Friends, the present phase of pandemic neglect is pathological. If that's you, please seek help. - It won't end well otherwise
Image Guess what the average of SARS infections will be by 2040, 18 years after billions were infected?

By contrast, six orders of magnitude fewer infections, ie ~ 8,000 documented SARS survivors vs. 400 million Long Covid (and billions of C19) survivors today thelancet.com/journals/eclin…
Aug 20, 2023 14 tweets 10 min read
Let’s do it. Pedro Pascal as SARS science. May need medical assistance here. 🤗 Pedro Pascal as programmed ribosomal frameshifting. 佩德罗·帕斯卡

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Pedro Pascal as feverish Shenzhen high speed train passenger. Prbably bending down in the photo to get his N95 w/eye protection 👍
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Aug 11, 2023 15 tweets 7 min read
Kind reminder that SARS is not novel and that giving it a new name (‘Covid’ ‘Corona’ 新型冠状病毒) just distracted 99% of people from the fact that we have 15-18 year SARS survivor studies. This is as non-novel as pandemics get. We had 54,000 studies on SARS-CoV & HIV - both crucial viruses used in lab research - BEFORE the pandemic started. Look I don’t know how to say this any more clearly sweeties. You got played.
Aug 8, 2023 97 tweets 54 min read
1. One thread to summarize the high-level SARS-CoV and climate narrative. Simple anecdote: every person alive today has personal links to past pandemics; study and learn from them. Look into the past to see your choice between change by policy vs. change by disaster more clearly. 2. As this massive 200+ tweet thread outlines, we can do better than "Let's halve the human lifespan" *by policy.* It became unwieldy 'cause several deletions stop algorithms from scanning it and sane minds from reading, so I may rewrite it in part again.
Aug 7, 2023 9 tweets 6 min read
We warned 3 years ago. Was easy to see for all who even casually looked at *pre-pandemic* literature. There were thousands of studies on SARS-CoV / HIV because both viruses are fundamentally similar.

As long as most people live in denial, "reinfection by policy" won't change. 🤷‍♂️
Image These tweets are not supposed to age like a good red wine. Ideally people listen, rub two synapses together, change behavior, and we can start to end this living nightmare.

Otherwise, good luck. You'll need it.
Aug 4, 2023 17 tweets 9 min read
1. The SARS-CoV envelope (E) and Orf3a protein are viroporins. Orf3a keeps the cell alive and allows chronic SARS infection (@RealCheckMarker #BoxOfNails for details).

Other viroporins: HCoV-229E 4a, HIV-1 Vpu, HCV p7, influenza A virus M2, ebola, dengue. frontiersin.org/articles/10.33…



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2. General virus structure background sciencedirect.com/science/articl…