Diencephalon location
- around the 3rd ventricle

The cavity of the diencephalon is ----- the 3rd ventricle
All of the structures of the diencephalon are around the 3rd ventricle, so the cavity of the diencephalon is the 3rd ventricle.

2/
Diencephalon embryology

- prosencephalon

3/ Image
Components (ETHOS)

Epithalamus (habenular & pineal)
- sleep-wake cycle

Thalamus
- relay center for sensory information

Hypothalamus (mammillary body & tuber cinereum)
- autonomic function & endocrine system

Optic nerve

Subthalamus
- inhibition of involuntary movements

4/ Image
Epithalamus

“melatonin control”

5/
Function

- connects limbic system to other parts of the brain
- controls the circadian rhythm

6/
Components - PHAS

Pineal gland
HAbenula
HAbenular commissure
Stria medullaris

7/ Image
Relation between

pineal gland
&
habenular commissure
&
posterior commissure

8/ Image
Relation between

Pineal gland
&
Habenula
&
Stria medullaris

9/ Image
Thalamus

“the major component of diencephalon”

10/
Structure

Thalami nuclei are divided by “Y” shaped white matter (internal medullary lamina)
- anterior, medial, and lateral nuclear groups

Pulvinar: Post end of Pos Pole of thalamus

11/
Function

Major sensory relay center

12/
Connections

Thalamic Radio – ABCDEFGHI (anticlockwise)

13/ Image
🅐 Anterior Nucleus

Alertness, Attention, Affect, Acute memory
*these are the main functions of limbic system – Papez circuit

Afferent: mammillary body
Efferent: cingulate gyrus

14/
🅑Ventral anterior nucleus

Basal ganglia

Afferent: globus pallidus and substantia nigra
Efferent: Broadmann area 6 (prefrontal and premotor cortex)

15/
🅒 Ventral lateral nucleus

Co-ordination & Cerebellum

Afferent: cerebellum (dentate nucleus) & basal ganglia
Efferent: Broadmann area 4 (primary motor cortex)

16/
🅓 Ventral posterior nucleus

Dermatome (sensory)

Afferent:
- Ventro-post-med (VPM):
> Medial: Mask (face & taste)

- Ventro-post-lat(VPL):
> VPL: Vibration, Pain, Pressure, Proprioception, Light touch and temperature

Efferent:
- Brodmann Area 3, 1, 2 (sensory cortex)

17/
🅔 Geniculate bodies

Eye and Ear

Lateral geniculate body: Light (eyes)
Afferent: optic tract
Efferent: calcarine sulcus (area 17)

Medial geniculate body: Music (ear)
Afferent: superior olive & inferior colliculus
Efferent: primary auditory cortex (area 41 & 42)

18/
🅕 Medial dorsal nucleus

Feelings (limbic system)

Afferent: amygdala & olfactory cortex
Efferent: prefrontal cortex & limbic system

19/
🅖 Pulvinar

Gloat (“fix” – control of eye movements)

Afferent: pretectal nucleus & superior colliculus
Efferent: association cortex

20/
🅗 Reticular nucleus

Halt thalamus

Afferent: cortex and interthalamic nuclei
* interthalamic connections largely inhibiton
Efferent: thalamic nuclei

21/
🅘 Intralaminar nucleus

Intent and arousal in Intralaminar nucleus
*alertness

Afferent: cortex, brainstem, and spinal cord
Efferent: cortex & basal ganglia

22/
Relation between

thalamus & internal capsule

23/ Image
What are the rings above thalamus?

Caudate nucleus
Stria terminalis
Lateral ventricle
Fornix

24/ Image
Caudate nucleus

“It is a rat”
Head, body, and tail (amygdaloid body)

Cheese – lentiform nucleus
Salad – internal capsule
Egg – thalamus

25/ Image
Hypothalamus!!!

26/ Image
Function
“HEAL”

Homeostasis of
Endocrine + ANS + Limbic systems

27/
Anatomy

- part of the diencephalon
- beneath the thalamus ("hypo"thalamus)
- posteriorly and dorsally to the optic chiasm

28/
Nucleus and lesions

29/ Image
Connections

“TSH Master Function to VID”
- 12 pathways

30/ Image
Mnemonic

“maintains homeostasis by regulating TANHATS”

Thirst and water balance
Adenohypophysis (anterior pituitary)
Neurohypophysis (posterior pituitary)
Hunger
Autonomic nervous system
Temperature
Sexual urges

31/
Summary figure

32/ Image
Subthalamus

33/
Function

“part of the indirect pathway of the basal ganglia”

34/
Components

Nuclear FIFA

Nuclear: subthalamic nucleus
Fasciculus: subthalamic fasciculus
Incerta: zona incerta
Forel: fields of Forel
Ansa: ansa lenticularis

35/ Image
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Jan 12
The Examination in Coma

“the father of modern neurological surgery”

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1/ Image
Definition

“a state of unarousable unresponsiveness”

Parts
a. level of consciousness
b. vital signs (BP & breathing pattern)
c. cranial nerves (fundoscopy + vision + brainstem)
d. motor & sensory
e. reflex
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Level of consciousness

Normal
Clouding of consciousness
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“pronator, cerebellar, parietal, and functional”

- pronator drift (pyramidal drift) was the 1st to be described
- Dr. Barre was the 1st to report it

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Pronator drift (Barre’s sign)

progress from distal to proximal

1st downward arm drift
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“Ready To Drink Cold Beer”

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Trunk (3): upper, middle, lower
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Branch (5)

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“formed by the anterior (ventral) rami of C5 to T1 spinal nerves”

Extent
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Tetanus
- it is different disease w/ different pathology

Tetanic contractions (physiologic tetanus)
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Tetany
- a type of tetanic contraction

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Clinical manifestations of tetany

“spasm and tonic contractions of the skeletal muscles, principally the distal muscles of the extremities”

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Meningeal signs

“Brudziński neck sign, Brudziński symphyseal sign, Brudziński cheek sign, Brudzinski's reflex”

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Meningitis
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Meningismus
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Meningism
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Mechanism

“maneuvers used to elicit meningeal signs produce tension on inflamed and hypersensitive spinal nerve roots, and the resulting signs are postures, protective muscle contractions, or other movements that minimize the stretch and distortion of the meninges and roots”

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Median nerve illustration by Guttmann (1939)

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Definition

“regions where single nerve roots supply distinct and non-overlapping areas of skin”

- small portion of dermatome
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- great variability

2/
Sensory zones

a.maximal zone: maximal area supplied by a peripheral nerve
- maximal=intermediate+autonomous

b.intermediate zone: area of overlap of the maximal zone of different peripheral nerves

c.autonomous zone: area exclusively supplied by a particular peripheral nerve
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