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Jan 30 • 6 tweets • 3 min read
Young Adults May Have Long COVID and Not Know it

Under 35 yrs old, stay in average shape, eat a mostly healthy diet,& have a strong immune system? You aren't likely to have symptoms from low exposure. That doesn't necessarily mean you avoided #LongCovid

tactnowinfo.substack.com/p/xbb15-and-ho…
"More than 200 symptoms have been identified with impacts on multiple organ systems."

"At least 65 million individuals worldwide are estimated to have long COVID"
"There are several hypothesized mechanisms for long COVID pathogenesis, including immune dysregulation, microbiota disruption, autoimmunity, clotting and endothelial abnormality, and dysfunctional neurological signalling"
Long COVID: major findings, mechanisms, and recommendations
Published January 2023

nature.com/articles/s4157…

#LongCovid
PCS developed among 30–60% of patients with asymptomatic or mild forms of COVID-19 on average.

The most common symptoms were fatigue, shortness of breath, cough, anosmia, and ageusia.

mdpi.com/2076-0817/10/1…
"Our results suggested that the long-term effects of asymptomatic SARS-CoV-2 infection exist, but the risk and frequency of developing long-term symptoms in asymptomatic SARS-CoV-2 infected persons are significantly lower than symptomatic COVID infection"

mdpi.com/1660-4601/20/2…

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More from @TactNowInfo

TACT Profile picture
Feb 1
🧵 What is causing the increasing number of excess deaths?

With each wave of COVID, excess deaths increase at the same time as COVID deaths. The surges in excess deaths do not follow the vaccine campaigns. Image
The most likely reason these deaths are not being classified as COVID is because they came in as heart attacks or strokes. Either they weren’t tested for COVID or, if they were, they still put the primary cause of death as something other than COVID.
2/ Image
In a study published on August 16, 2020 (pre-vax), they noted, "coronaviruses are known to affect the cardiovascular system.” This was an early warning when they noted that COVID-19 itself might aggravate the myocardial injury by causing the “release of multiple cytokines.. 3/
Read 18 tweets
TACT Profile picture
Jan 31
The extremely contagious, immune suppressive variants are ripping through schools & homes, pushing prevalence in wastewater back up much faster than the past few years. 1/ Image
The Western U.S. and North Central regions are seeing the expansion occur faster as XBB.1.5 presence grows in these regions. Everyone is susceptible to infection, long-term organ infection, & Long COVID. 2/ Image
Mississippi, Tennessee, North Dakota, and Minnesota have the highest infection rates, according to COVIDActnow.org
3/ Image
Read 21 tweets
TACT Profile picture
Jan 30
Wastewater-based monitoring of SARS-CoV-2 at UK airports and of arriving flights shows a high prevalence of COVID

➡️ "All samples from sewers at the arrival terminals of Heathrow and Bristol airports, and 85% at Edinburgh airport, were positive
1/
"This suggests a high COVID-19 prevalence among passengers and/or airport staff members."

"Samples derived from aircraft also showed 93% SARS-CoV-2 positivity. No difference in viral prevalence was found before, and after COVID-19, travel restrictions were lifted." 2/
As we have been saying for 3 years, the only way to slow down the global spread of new variants is to test all passengers upon arrival and require a 7-day isolation period, with 2 negative test 48 hours apart to clear. 3/
Read 5 tweets
TACT Profile picture
Jan 30
"Clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID"

"Interferon-activated naïve T cells differentiate into memory T cells in adults but not children."
1/
"Adults but not children develop robust memory T cell responses to SARS-CoV-2."

This isn't good news. Children do not have the same memory T-cell protection adults develop, so that would mean they are using more naive T-cells. 2/
"These data suggest that rapid clearance of SARS-CoV-2 in children may compromise their cellular immunity and ability to resist reinfection."
3/
Read 10 tweets
TACT Profile picture
Jan 30
🧵How close is COVID to becoming like a much more transmissable MERS-CoV?

According to the WHO, approximately 35% of patients with MERS-CoV have died” (5) Another study shows the case fatality rate at 32.7%. (6)  1/
If there is any chance that evolution is moving towards something closer to how MERS impacted people, then we should all be working towards limiting transmission.

Are we headed in that direction?
2/
Hopefully, it will never become anything like MERS, but wait, it is already similar to MERS.

“MERS-CoV efficiently infected T cells from the peripheral blood and from human lymphoid organs, including the spleen and the tonsil." 3/
Read 15 tweets
TACT Profile picture
Jan 29
Extremely contagious immune suppressive, organ infecting variants ripping through schools & homes.
U.K. Zoe data shows what is occurring everywhere after the holidays when schools reopen. The exponential growth was reset but is quickly expanding with zero protection for children.
XBB.1.5 increases to over 60% of sequenced cases.

XBB.1.9 may make it harder for our immune system to fight back. It's on the move and expanding fast.

tactnowinfo.substack.com/p/xbb15-increa…
Heart Dysfunction💔

Previously Healthy Children w/Asymptomatic or Mild COVID Infection

tactnowinfo.substack.com/p/heart-dysfun…
Read 18 tweets

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