Thread by @sulmoney

#MedMondays for today, let's do #Adderall, THREAD🧵 :

1/ Adderall is a stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy; it works by increasing the levels of neurotransmitters in the brain, including dopamine and norepinephrine.

2/ Common side effects of Adderall include loss of appetite, trouble sleeping, and stomach problems. More serious adverse effects include heart problems, anxiety, mood swings or changes, and potential for dependence.

3/ Adderall is available in immediate-release and extended-release formulations, and it can be taken orally in tablet or capsule form, as well as some liquid formulations and oral disentegrating tablets (ODT): Adzenys, Dyanavel, Mydayis, and Vyvanse are all essentially Adderall.

4/ The history of Adderall dates back to the 1930s, when it was first developed as a treatment for behavioral disorders in children. A precursor, Benzedrine, was used extensively by soldiers in WW2 for alerness and staying awake.

5/ Adderall misuse has become a significant concern, as individuals can misuse it to enhance cognitive performance and study abilities. This can lead to substance use disorders and overdose. According to the #NSDUH , Adderall misuse rates are higher among young adults aged 18-25.

6/ But treatment is important: journal of @AACAP found Adderall improved cognitive function, behavior, and quality of life in children with ADHD. A meta-analysis of clinical trials published in @APAPubJournals found it is effective in improving symptoms in both children & adults.

@AACAP @APAPubJournals 7/ Adderall (mixed amphetamine salts) is NOT methamphetamine. While the chemical structures are similar, differences in chemical structures mean different substances. Regardless, #methamphetamine is still a medication that can be prescribed & is FDA-approved for ADHD & obesity.

@AACAP @APAPubJournals 8/ Appropriate use of Adderall (any medication) involves taking the medication as prescribed. Misuse involves taking the medication without a prescription or in a manner not prescribed, and may involve taking a higher dose than prescribed/taking the medication more frequently.

@AACAP @APAPubJournals 9/ When the effects of Adderall wear off, some individuals may experience a phenomenon known as an "Adderall crash." This is characterized by symptoms such as fatigue, depression, irritability, and a general feeling of physical and mental exhaustion.

@AACAP @APAPubJournals 10/ Recently, there has been a shortage of Adderall in the US, leading to difficulties for patients who need it. The shortage is due to production issues, increased demand, COVID-19 supply chain disruptions, and the rise of online pill mills like @doneadhd and @cerebral