🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria week 7, 2023 across all regions. Current analysis includes samples until February 8th allowing faithful nowcasting, sample numbers dropping though. A collaboration of #AGES@agesnews and @IMBA_Vienna/@oeaw. 1/6
Current significant growth in incidence is almost exclusively due to XBB.1.5, that reached >50% of cases now. 2/6
Only very few other lineages continue to show growth in absolute numbers as visualized when extrapolating shares of lineages to absolute reported numbers. 3/6
FYI: Based on sewage analysis in Austria (blue), the current incidences surpass the BA.1-, BA.2-, and both BA.5-peaks while the reported case rate (orange) underlying the above analysis is significantly lower.
(open image for full timeline) 4/6 abwassermonitoring.at/dashboard/
Full genome data from GISAID also illustrate growth of XBB.1.9.1, but this lineage will in all likelihood not become dominant any more before the XBB wave has peaked. 5/6
The observed increase of XBB.1.5 is fairly synchronous across Austria. Shares of other lineages that will probably decline now was somewhat uneven.
👏🏼👏🏼Time to thank my team again for this amazing work every week! 🙇🏼♂️ 6/6
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Eine Initiative, das gesellschaftliche Corona-Trauma aufzuarbeiten, wie Kanzler Nehammer anregt, wäre ja prinzipiell sehr begrüßenswert.
Zuerst sollten wir aber diskutieren, daß das Virus jeden einzelnen und uns gemeinsam an die Grenzen gebracht hat. 1/ derstandard.at/story/20001435…
Deshalb sollten die individuellen und gemeinsamen Be- und Überlastungen verarbeitet werden. Wer wurde wann warum über die Maßen belastet? Auch wer hat wann wo ungerecht profitiert?
2/
Aber nochmals: Die Ängste, die Belastungen, das Leid, das die Pandemie verursacht hat, ist vor allem eine Naturkatastrophe und nicht die Schuld von irgendjemand. Gegenseitige Schuldzuweisungen machen es nicht viel besser.
3/
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria week 2, 2023 across all regions. Current analysis includes samples until January 5th allowing faithful nowcasting. A collaboration of #AGES@agesnews and @IMBA_Vienna/@oeaw. 1/5
The variant situation for Austria changed dramatically between the years. While we had a swarm of lineages growing in numbers until Christmas, it is now just one lineage showing growth: XBB.1.5. 2/5
XBB.1.5 is a descendent of the strongly immune evasive recombinant XBB that now acquired a mutation improving binding to the ACE2 receptor on human cells and thereby infectivity. It is observed across Austria now. Nowcasting predicts it to be currently at ~8%. 3/5
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria. This is our analysis run number 100, so I would like to start by thanking the entire SARSeq team. One hundred successful analysis rounds straight is an amazing achievement, congratulations to everyone! 1/
This collaboration of health authorities and academia showcases the innovative power and value of academic institutions that stepped in in response to the pandemic. Globally such solutions were rather the rule than the exception, so big shoutout to all my colleagues worldwide!
3/
Important work on the wild reservoirs of SARS-CoV 1 and 2 and a new SARS-CoV-SARS-CoV-2 recombinant in a paper that just went online summarized here 🧵: biorxiv.org/content/10.110…
1/11
Yunnan Province at the southern tip of China is a hotspot for bats and bat viruses. Closest relatives of SARS-CoV as well as SARS-CoV-2 are found here and different bat species are living in caves together.
2/11
In this important work, researchers analyzed 149 bats individually to study what virus they carry and found 41 different ones, 70 bats were positive for at least one virus (47%), amongst them 1.5 viral species were found on average per individual.
3/11
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria in week 42 across all regions. Nowcasting in dashed box shows the current situation. A collaboration of #AGES@agesnews and @IMBA_Vienna/@oeaw. 1/6
BA.5 with R346T has reached ~25% now. New variants such as BQ.1(.1) and XBB show clear growth. BQ.1(.1) currently at ~8%, XBB<1%. 2/6
Due to the good weather (see journals.plos.org/ploscompbiol/a…) and declining case counts of BA.5 we currently observe a strong reduction in absolute numbers. 3/6
🧵To mask or not to mask, this is the question again.
With winter starting in the northern hemisphere, masks are discussed many places. Some thoughts within the range of realistic options:
A.For societies
B.For individuals
A. Any form of enforced mask mandate as seen in some countries previously of course is a stress test for societies and generally disfavoured by most, but also requested by many. Some arguments for society level reactions:
A.1 One might argue that dampening one wave with masks just means the next wave is higher. Connected vessels. Only true however if we assume that one wave generates immunity against the next, this was neither true always in the past nor is it projected to be the case this winter.