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Apoorva Mandavilli Profile picture
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Feb 24 • 5 tweets • 4 min read
SCOOP -- and a bit of relief for your weekend: Cambodia says the 11 other contacts of the girl who died of #H5N1 human bird flu are all negative for the virus. So far, only her father is positive.
w/ @EmilyAnthes

nytimes.com/2023/02/24/hea…
@EmilyAnthes What exactly is bird flu and what do we know about #H5N1 human? Here's your primer:

nytimes.com/2023/02/24/hea…
@EmilyAnthes Any reports of #H5N1 infection in people warrant investigation to confirm that the virus has not yet adapted itself to human-to-human transmission. More details on the Cambodia outbreak:

nytimes.com/2023/02/24/hea…
@EmilyAnthes Genetic analysis can reveal whether #H5N1 has acquired mutations that help it spread among people -- but in this case, epidemiology is more likely to be informative

nytimes.com/2023/02/24/hea…
@EmilyAnthes Is a bird flu pandemic inevitable? Or can we prevent spillover into humans?

nytimes.com/2023/02/24/hea…

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More from @apoorva_nyc

Apoorva Mandavilli Profile picture
Aug 15, 2022
SCOOP: The feds have been relying on emails to order and deliver #monkeypox vaccine, Jynneos, instead of the well-oiled machine run by the CDC for routine immunizations:

nytimes.com/2022/08/15/hea…
The stockpile where Jynneos is stored was never meant to handle orders from states. That has meant doses missing in transit for days, delivered in the dead of night, arriving refrigerated rather than frozen, and shipped to just five sites in each state, regardless of size.
The feds introduced a new system to states 2 wks ago, trained them on it 4 days before that. But that system is also not integrated with state immunization databases, meaning state officials have to do manual data entry into two systems, instead of one automated one.
Read 5 tweets
Apoorva Mandavilli Profile picture
Jun 11, 2022
Sunset
No filter. Seriously.
Read 5 tweets
Apoorva Mandavilli Profile picture
Mar 11, 2022
My son tested positive for Covid in a school test, and so I am now listening to a NYC DOH person explain to me, in excruciating detail, that Covid is caused by a virus, and a long list of symptoms to say yes/no to.

It's been going on for many, many minutes already
This is really super, super excruciatingly detailed. Now we are on the isolation guidance
It's a bit strange that they don't let you opt out of any of the info. How many parents have time for a 16-minute call right smack at dinner time?
Read 5 tweets
Apoorva Mandavilli Profile picture
Feb 28, 2022
NEW: The coronavirus vaccine made by Pfizer-BioNTech is much less effective in preventing infection in children ages 5 to 11 years than in older adolescents or adults, according to a large new set of data collected by health officials in New York State

nytimes.com/2022/02/28/hea…
For eg: During the week ending Jan. 30, the vaccine’s effectiveness against infection was 67 percent in 12-year-olds but just 11 percent in 11-year-old children.
Effectiveness against hospitalization was also less in kids 5-11 than in older kids (48% vs 73%), but these numbers are less reliable because so few kids were in hospitals that the margins of errors are wide.
Read 5 tweets
Apoorva Mandavilli Profile picture
Feb 20, 2022
NEW: Two full years into the pandemic, the CDC has withheld critical Covid data on boosters, hospitalizations and, until recently, wastewater analyses.

nytimes.com/2022/02/20/hea…
For more than a year, CDC has collected data on Covid related hospitalizations broken down by age, race and vaccination status. But it has not made most of the information public.
When the C.D.C. published the first significant data on the effectiveness of boosters in adults younger than 65 two weeks ago, it left out the numbers for 18- to 49-year-olds, the group least likely to benefit from extra shots.
Read 5 tweets
Apoorva Mandavilli Profile picture
Feb 8, 2022
Redoing this tweet to be super clear. Texas has breakdown of deaths by age and vaxx status. Only 8% are in vaxxed people, and only 0.03% of them in vaxxed people under 50. Corresponding number is 12% for unvaxxed, showing clearly, even in that age group, the power of vaccines
But 0.03% of deaths in vaccinated people under 50 also illustrates what the CDC data posted last week show -- that boosters offer only incremental benefit in terms of severe illness/death to young people, and the benefit is most likely to those with other conditions.
This is not to say no one under 50 should get boosted because boosters do prevent infection for a little while, and would mitigate virus circulation during a surge.
Read 5 tweets

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