Thread by @DavidCranmerUn1

RESILIENCE Launches to Change the Future of Medicine through Manufacturing Innovation

Company founded by ARCH Venture Partners' Robert Nelsen has raised over $800 million in capital, including from co-founder 8VC.

#RESILIENCE prnewswire.com/news-releases/…

Dr. Rahul Singhvi is a global leader in the life sciences industry and serves as the Chief Executive Officer of National Resilience, Inc.
Most recently, Singhvi was an Operating Partner at Flagship Pioneering, a Boston-based life sciences innovation firm, where he was responsible

for founding and operating companies launched from Flagship’s innovation foundry, Flagship Labs.

Flagship Pioneering was founded in Cambridge in 1999 by Noubar Afeyan and Ed Kania under the name NewcoGen (short for "new company generation"), but later changed its name to

Flagship Ventures, and again in 2016 to Flagship Pioneering.
In late 2010, Flagship formed Moderna, which focuses on drug discovery, drug development, and vaccine technologies based exclusively on messenger RNA (mRNA) technology.

In 2013, Flagship helped fund the creation of

Editas Medicine to use CRISPR gene editing for the development of pharmacological therapies, originally based on the genetic engineering protein Cas9. Editas was founded by Feng Zhang, Jennifer Doudna, George Church, J. Keith Joung, and David R. Liu. Doudna would later win the

Nobel Prize in Chemistry in 2020 for her work on CRISPR.

In 1988, Noubar Afeyan founded PerSeptive Biosystems and served as its CEO. The company's annual revenues grew to $100 million and in 1998 was acquired by PerkinElmer/Applera and became CBO of Applera. There he oversaw the

creation of Celera Genomics.

Originally headquartered in Rockville, Maryland (relocated to Alameda, California), Celera Genomics was established in May 1998 by PE Corporation (later renamed to Applera), with Dr. J. Craig Venter from The Institute for Genomic Research (TIGR) as

its first president. While at TIGR, Venter and Hamilton Smith led the first successful effort to sequence an entire organism's genome, that of the Haemophilus influenzae bacterium.

Celera sequenced the human genome at a fraction of the cost of the publicly-funded Human Genome

Project (HGP), using about $300 million of private funding versus approximately $3 billion of taxpayer dollars. However, a significant portion of the human genome had already been sequenced when Celera entered the field, and thus Celera did not incur any costs with obtaining the

existing data, which was freely available to the public from GenBank.

Craig Venter began his college education in 1969 at a community college, College of San Mateo in California, and later transferred to the University of California, San Diego, where he studied under biochemist

Nathan O. Kaplan.

From 1942 to 1944, Kaplan participated in the Manhattan Project, and then spent a year as an instructor at Wayne State University.

Jerome Horwitz of the Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine first synthesized AZT

in 1964 under a US National Institutes of Health (NIH) grant.

In 2000, Craig Venter and Francis Collins of the National Institutes of Health and U.S. Public Genome Project jointly made the announcement of the mapping of the human genome, a full three years ahead of the expected

end of the Public Genome Program. The announcement was made along with U.S. President Bill Clinton, and UK Prime Minister Tony Blair.

In June 2005, Craig Venter co-founded Synthetic Genomics, a firm dedicated to using modified microorganisms to produce clean fuels and

biochemicals. In July 2009, ExxonMobil announced a $600 million collaboration with Synthetic Genomics to research and develop next-generation biofuels.

ExxonMobil's earliest corporate ancestor was Vacuum Oil Company, though Standard Oil is its largest ancestor prior to its

breakup. The entity today known as ExxonMobil grew out of the Standard Oil Company of New Jersey (or Jersey Standard for short), the corporate entity which effectively controlled all of Standard Oil prior to its breakup. Jersey Standard grew alongside and with extensive

partnership another Standard Oil descendant and its future merger partner, the Standard Oil Company of New York (Socony), both of which grew bigger by merging with various third companies like Humble Oil (which merged with Jersey Standard) and Vacuum Oil (merged with Socony).

Founded in 1923, Ethyl Corp was formed by General Motors and Standard Oil of New Jersey (Esso). General Motors had the "use patent" for tetraethyllead (TEL) as an antiknock, based on the work of Thomas Midgley Jr., Charles Kettering, and later Charles Allen Thomas, and Esso had

the patent for the manufacture of TEL.

A direct descendant of Standard Oil, Mobil was originally known as the Standard Oil Company of New York (shortened to Socony) after Standard Oil was split into 34 different entities in a 1911 Supreme Court decision. Socony merged with

Vacuum Oil Company, from which the Mobil name first originated, in 1931 and subsequently renamed itself to Socony-Vacuum Oil Company. Over time, Mobil became the company's primary identity, which incited another renaming in 1963, this time to Mobil Corporation.

Synthetic Genomics was founded in the spring of 2005 by J. Craig Venter, Nobel Laureate Hamilton O. Smith, Juan Enriquez, and David Kiernan.

In 1992, Craig Venter was a researcher at the National Institutes of Health (NIH). He began The Institute for Genomic Research (TIGR)

during the same time and was part of the determination of the human genome.

In 2001 anthrax attacks, TIGR worked with the National Science Foundation and the FBI to sequence the strain of Bacillus anthracis used in bioterrorism attacks.

In 1950 Harry S. Truman signed Public

Law 507, or 42 U.S.C. 16 creating the National Science Foundation which provided for a National Science Board of twenty-four part-time members. In 1951 Truman nominated Alan T. Waterman, chief scientist at the Office of Naval Research, to become the first National Science

Foundation Director.

Alan T. Waterman joined the faculty of the University of Cincinnati, and married Vassar graduate Mary Mallon (sister of H. Neil Mallon) in August 1917.

Henry Neil Mallon (January 11, 1895 – March 1, 1983) was an American businessman. He served as the chair

of the board, president, and director of Dresser Industries (Cleveland, OH) (now Halliburton).

Henry Neil Mallon was born in Cincinnati on January 11, 1895. He graduated from Yale University, where he became friends with Prescott Bush.

Mallon hired George Herbert Walker Bush to

work for Dresser Industries in West Texas shortly after he graduated from Yale University. He was also an early investor in Zapata Corporation, founded by Bush. Bush in turn named one of his sons, Neil Mallon Bush, after his mentor.

Following Dresser's death, his descendants

decided to sell it, and in 1928 the Wall Street investment-banking firm of W. A. Harriman and Company, Inc.

Better known as Averell Harriman, he was born in New York City, the son of railroad baron Edward Henry Harriman and Mary Williamson Averell. He was the brother of

E. Roland Harriman and Mary Harriman Rumsey. Harriman was a close friend of Hall Roosevelt, the brother of Eleanor Roosevelt.

Roland, whom friends and family sometimes called "Bunny," was educated at Groton School, from which he graduated in 1913, and

Yale University (B.A., 1917), where he was a member of Psi Upsilon fraternity. He was also a member of Skull and Bones with his classmate and friend Prescott Bush.

Using money from his father, he established the W.A. Harriman & Co banking business in 1922. His brother Roland

joined the business in 1927 and the name was changed to Harriman Brothers & Company. In 1931 it merged with Brown Bros. & Co. to create the highly successful Wall Street firm Brown Brothers Harriman & Co. Notable employees included George Herbert Walker and his son-in-law

Prescott Bush.

After immigrating to Baltimore in 1800 and building a successful linen mercantile trading business, Alexander Brown and his four sons co-founded Alex. Brown & Sons. In 1818, one son, John Alexander Brown, traveled to Philadelphia to establish John A. Brown and

Co. In 1825, another son, James Brown, established Brown Brothers & Co. on Pine Street in Lower Manhattan and relocated to Wall Street in 1833. This firm eventually acquired all other Brown branches in the U.S. Another son, William Brown, had established William Brown & Co. in

England in 1810, which was renamed Brown, Shipley & Co. in 1839 and became a separate entity in 1918.

After spending time in Europe, Montagu Collet Norman joined Martins Bank, where his father was a partner, in 1892, Brown, Shipley & Co., where his maternal grandfather was a

partner, in 1894, and Brown Bros. & Co. of New York, in 1895. He became a partner in Brown Shipley in 1900 before leaving for South Africa, and retired from them in 1915.

Norman was a close friend of the German Central Bank President Hjalmar Schacht, who served in Hitler's

government as President of the Reichsbank and Minister of Economics between 1934 and 1937. Norman was also so close to the Schacht family that he was godfather to one of Schacht's grandchildren. Both were members of the Anglo-German Fellowship and the

Bank for International Settlements.

Norman authorized the transfer of Czech gold from Czechoslovakia's No. 2 account with the Bank for International Settlements to the No. 17 account, which Norman was aware was managed by the German Reichsbank. Within ten days the money had been

transferred to other accounts. In the fall of 1939, two months after the outbreak of World War II, Norman again supported transfers of Czech gold to Hitler's Germany. On this occasion His Majesty's Government intervened to block Norman's initiative.

Priscilla Cecilia Maria Reyntiens, The Lady Norman, CBE, JP (20 March 1899 – 5 April 1991) was a London councillor, board member, and supporter of mental health and nursing institutions.
Her father Major Robert Reyntiens was Aide de Camp to King Leopold II of Belgium.

Leopold ran the Congo by using the mercenary Force Publique for his personal gain. He extracted a fortune from the territory, initially by the collection of ivory and, after a rise in the price of natural rubber in the 1890s, by forced labour from the native population to harvest

and process rubber.

Leopold's administration of the Congo Free State was characterized by atrocities and systematic brutality, including forced labour, torture, murder, kidnapping, and the amputation of the hands of men, women, and children when the quota of rubber was not met.

In 1890 and in one of the first uses of the term, George Washington Williams described the practices of Leopold's administration of the Congo Free State as "crimes against humanity".