Kai Kupferschmidt Profile picture
Feb 26 5 tweets 2 min read
Here are the details on the Cambodian #H5N1 cases from @WHO:
An 11 year old girl fell sick February 16, died February 22
Her father is positive, but asymptomatic and in isolation
11 other close contacts tested negative

Virus belongs to clade 2.3.2.1c

who.int/emergencies/di…
“A joint animal-human health investigation is underway in the province of the index case to identify the source and mode of transmission. Additionally, a high-level government response is underway to contain any further spread of the virus.”
“Currently, there is no vaccine widely available to protect against avian influenza in humans. WHO recommends that all people involved in work with poultry or birds should have a seasonal influenza vaccination to reduce the potential risk of reassortment”
Context:
These are the first human H5N1 infections reported in Cambodia since 2014.
Since 2003 there have been 58 cases of human infection with H5N1 reported in the country, including 38 deaths (CFR 66%)
2003-2009: 9 cases and 7 deaths
2010-2014: 47 cases and 30 deaths
“While further characterization of the virus from these human cases is pending, … WHO assesses the risk to the general population posed by this virus to be low.”

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More from @kakape

Feb 28
Two weeks ago I met with @JeremyFarrar to talk for our @pandemiapodcast.
He was on his way to the @MunSecConf and we discussed Covid, H5N1 and what connects those trying to prevent acts of terror and those fighting pandemics

Episode (in German) is here:
superelektrik.de/pandemia/updat…
@JeremyFarrar @pandemiapodcast @MunSecConf On Covid:
Farrar says he still wears a mask on public transport. "But it doesn't worry me that most other people don't. There's no need, in my view, in most of the world for any restrictions."
"We're in a good position", he says.
@JeremyFarrar @pandemiapodcast @MunSecConf "But we cannot leave open the nonzero chance of something bad happening", says Farrar. "And in my view, what that means is continuing surveillance. And unfortunately, many countries have stopped surveillance and I think that's a mistake."
Read 18 tweets
Feb 24
Cambodia has informed @WHO of two confirmed cases of #avianinfluenza #H5N1, an 11 year old girl that died and another member of her family, @SCBriand just said in a @WHO press conference. Field investigations are going on, she said.
@WHO @SCBriand It's crucial, of course, to learn more about what exactly happened incl. whether there are other possible cases, how the cases were infected and whether there was any human-to-human transmission.
Read 10 tweets
Feb 21
When I talked to @BrendaCrabtreeR a few days ago about #mpox she told me the story of a patient she helped to treat in Mexico City in June: a man in his 30s who did not know that he was also living with HIV.

science.org/content/articl…
@BrendaCrabtreeR The young man’s immune system was so weak it could not keep the monkeypox virus in check. He had painful necrotizing lesions spreading across his skin and the virus had spread to his lungs too. “He just kept getting worse and worse and worse,” @BrendaCrabtreeR told me.
@BrendaCrabtreeR No vaccine or treatments are available in Mexico. Desperate, the doctors transferred blood plasma from a colleague that had been vaccinated in the US to the patient hoping the antibodies might help fight the virus. But they could not save the patient. He died a few weeks later.
Read 14 tweets
Feb 17
There has been a spate of travellers returning from Cabo Verde recently infected with the bacterium Shigella sonnei.
“Most cases have stayed in five-star, all-inclusive hotels in the Santa Maria region of the island Sal”, @ECDC_EU writes in a risk assessment it just published.
The report notes 258 cases (see table). “The most recent cases were reported in Sweden on 19 January 2023, suggesting an ongoing moderate risk of new infections among travellers in Cabo Verde, particularly among those staying in the Santa Maria region of Sal.”
Interestingly most cases are women (ratio of 2.5:1). “This is unusual for shigellosis outbreaks, which are often reported among men who have sex with men (MSM). In foodborne shigellosis outbreaks however, a slightly larger proportion of females can be observed among cases…”
Read 8 tweets
Feb 15
Marburg outbreak in Equatorial Guinea stands at 9 deaths (1 confirmed as Marburg, 8 suspected), 16 suspected cases in health facilities and 21 asymptomatic contacts being monitored at home, says @drtedros in @WHO presser.
@DrTedros @WHO The outbreak is in the border region with Gabon and Cameroon.
"So far, no confirmed cases have been reported in Cameroon or Gabon", says @DrTedros. "But WHO is working with the Ministry of Health of Cameroon to investigate an alert in that country."
@DrTedros @WHO #Mpox remains a public health emergency of international concern:
The emergency committee met on Friday. "The committee has advised me that in its view #mpos remains a global health emergency, and I have accepted that advice", says @DrTedros.
Read 4 tweets
Feb 9
Es hat ne Weile gedauert, aber wir sind endlich wieder da mit @pandemiapodcast!
Neues Logo, neue Musik, alte Crew und wie immer tolle Themen und Gäste:
Dieses Mal geht es um #longcovid, #Vogelgrippe #H5N1 und neue #Impfstoffe

superelektrik.de/pandemia/updat…
@pandemiapodcast Vielen Dank an @C_Scheibenbogen, @florian_krammer, @CorneliaBetsch, @PeacockFlu, Mitchell Warren und vor allem an @marga_owski, die uns einen Einblick in ihr Leben mit #longcovid gewährt hat...
@pandemiapodcast @C_Scheibenbogen @florian_krammer @CorneliaBetsch @PeacockFlu @marga_owski Wir kommen jetzt auch wieder regelmäßiger. Versprochen! Und wir wollen in Zukunft immer auch versuchen, einige Hörerfragen zu beantworten. Also schreibt uns gerne an pandemia@superelektrik.de oder einfach hier bei Twitter...
Read 4 tweets

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