Tom Andrews Profile picture
Mar 6, 2023 5 tweets 4 min read Read on X
Official from the U.S. CDC (27 Feb 2023)
"Emerging evidence suggests that SARS-CoV-2, the virus that causes COVID-19, can have lasting effects on nearly every organ and organ system of the body weeks, months, and potentially years after infection"
#NotMild
cdc.gov/nchs/data/nvss…
#PreventSARSCOV2Reinfection
Public Health Ontario's Evidence & Risk Assessment for SARS-COV-2
(June 23 2022) stated:
"Preventing high levels of COVID-19 community transmission may mitigate the
incidence of PACS (long COVID) and its long term impacts"
publichealthontario.ca/-/media/Docume…
Official from Public Health Ontario SARS-COV-2 Risk Assessment (June 2022)
"Emerging evidence indicates that reinfection adds risk of all-cause mortality, hospitalization and
adverse health outcomes during acute & post-acute SARS-CoV-2 reinfection."
#DontGetReinfectedBySARSCOV2
Public Health Ontario SARS-COV-2 Risk Assessment
"Additionally, the risk and burden may increase in a graded manner according to the number of infections, which suggests preventing reinfection could reduce overall SARS-CoV-2 burden of death & disease"
#DontGetReinfectedbySARSCOV2
Official from Public Health Ontario SARS-COV-2 Risk Assessment (June 2022):
"Current COVID-19 vaccines and previous SARS-CoV-2 infection do not provide sterilizing immunity (i.e., full protection from infection or reinfection)."
#DontGetReinfectedbySARSCOV2

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More from @0bj3ctivity

Aug 23
I know the risks, have known this was almost certainly coming for years now, but seeing it already in a 7 yr old, makes me want to be sick😔

I have tried to warn people in my family to keep their children safe & avoid repeated COVID reinfections but they don't want to hear it 😔
If seven year olds are already being seen with problems like this, and it's due to their SARS-COV-2 infections, what hope will so many kids have, reinfected again & again, at least once a year?

Ok hopefully it will only be a subset

But we don't know how big a subset yet
And no, it's not even ok for there to be one kid left avoidably harmed by COVID

But we know it's not just one. It's not just hundreds. Not even thousands. Already millions worldwide 😔

Read 12 tweets
Jul 2
Severe acute respiratory syndrome coronavirus 2 infection is linked to significant liver injury, emerging from the facilitated entry of the virus into liver cells, including cholangiocytes and endothelial cells, due to increased receptor expression🧵

1/x
wjgnet.com/1007-9327/full…
This invasion triggers critical cellular alterations such as mitochondrial swelling, endoplasmic reticulum dilation, and hepatocyte apoptosis.

2/x
Confirmed by biopsy or autopsy, the presence of viral particles in liver tissues correlates with extensive histological damage, characterized by necrosis, steatosis, cholestasis, and inflammation.

3/x
Read 43 tweets
Jun 29
Diabetic? Wear a 😷

"hyperglycemic conditions enhanced the viral entry receptor expression, infectivity, & susceptibility of SARS-CoV-2-induced cell death in the blood retinal barrier cells confirming reported heightened pathology in comorbid populations"
journals.plos.org/plospathogens/…
"...intranasal exposure (to SARS-COV-2 virus, ie simulating inhalation) not only resulted in SARS-CoV-2 spike (S) protein presence in different ocular tissues but also induces a hyperinflammatory immune response in the retina..."
"... Additionally, the long-term exposure to viral S-protein caused microaneurysm, retinal pigmented epithelium (RPE) mottling, retinal atrophy, & vein occlusion in mouse eyes..."
Read 13 tweets
May 4
"Cattle have the potential to act as a mixing vessel for novel IAV generation"

"The avian and human influenza A virus receptors sialic acid (SA)-α2,3 and SA-α2,6 are widely expressed in the bovine mammary gland" 🧵

biorxiv.org/content/10.110…
Reason cows fare better than many species?

"duck & human IAV receptors were widely expressed in the bovine mammary gland, whereas the chicken receptor dominated the respiratory tract. In general, only a low expression of IAV receptors was observed in the neurons of the cerebrum"
Read 5 tweets
May 4
@CCSDMaskUp @RickABright @GISAID @USDA "A striped skunk was found dead in proximity to deceased Canada geese in late February in Tompkins County"

.cwhl.vet.cornell.edu/article/highly…
@CCSDMaskUp @RickABright @GISAID @USDA "apparently healthy" raccoons (Japan though here, not current)

"1,088 serum samples collected from animals captured in ... eradication program over 3 periods in Japan ... during 2005–2009 for a serologic survey of avian influenza virus (H5N1) infection"
ncbi.nlm.nih.gov/pmc/articles/P…
@CCSDMaskUp @RickABright @GISAID @USDA "Bird flu detected in two dead mountain lions"
March 30, 2023
.benitolink.com/bird-flu-detec…
Read 4 tweets
Apr 24
"reviewed studies generally indicate that human norovirus (NoV), Hep A (HAV) and Hep E (HEV) possess a high heat stability. Heating at 70-72 °C for 2 min significantly reduces infectious titers, but often does not result in a >4 log10 decrease"
.pubmed.ncbi.nlm.nih.gov/38290272/#:~:t…
"Resistant fractions of viruses may remain infectious in thermal inactivation processes and inactivation of newly discovered or enveloped viruses in thermal food preparation processes should not be assumed without further testing"

ncbi.nlm.nih.gov/pmc/articles/P…
"Viruses do not follow log‐linear thermal inactivation kinetics and the thermostability of parechovirus and influenza virus is similar to that of proven foodborne viruses"

ncbi.nlm.nih.gov/pmc/articles/P…
Read 8 tweets

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