Thread by @ToshiAkima

Sir Ronald Aylmer Fisher, the methodological father of the modern RCT as practised in medicine today, was a eugenicist. His most fanatical GBD heirs today remain quasi-eugenicist Social Darwinist RCT ideologues. Article by @RichardEvans36 🧵
12ft.io/proxy?q=https%…

@RichardEvans36 is a hugely respected British historian and one of the leading authorities on the history of the Third Reich. It is simply not possible to paper over his sober analyses in the glib and shameful way that apologists in @HeredityJournal did.
nature.com/articles/s4143…

The authors do nothing to respond to the fact that the use of gas chambers for euthanasia was developed in the eugenicist Aktion T4 that predated the later Judenaktion (Final Solution). They conveniently gloss over facts brought to light by Sir Richard, such as these.

@RichardEvans36 knows because he wrote what is still the definitive introductory textbook to the subject (volume 3 of his monumental Third Reich tetralogy). Attempts to extricate Fisher's eugenics from the taint of genocide are unconvincing. amazon.com/Third-Reich-Wa…

Well after the Holocaust, in the 1950s, while defending his friend Verschauer (the PhD supervisor of Josef Mengele), RA Fisher continued to uphold the notion that there were profound differences in the intelligence of races.

It is hardly surprising that RA Fisher's heirs today wilfully holdup the acceptance of respirators for the mitigation of aerosol spread of COVID, rejecting aerosol physics by demanding RCTs in the most flat-earthed manner possible. #COVIDisAirborne

https://twitter.com/toshiakima/status/1627184313593909248?s=61&t=sBByeWSbsztYGCU9PUQLjg

The RCT fanatics who push for RCTs of a physically engineered safety device are the same hardliners who oppose all public health measures to mitigate infection, except vaccination, as it is supported by RCT evidence.

They demand the dropping of physical mitigations in favour of a mass infection strategy aiming first for herd immunity, then for the use of SARS-CoV-2 as a natural booster to engender so-called “hybrid immunity”—a euphemism for a mass infection strategy.

This ideology has unleashed a quasi-eugenicist, Social Darwinist democide on a vast scale upon the vulnerable in society as COVID is left to rip. All rationalised as the price paid for progress necessary to stimulate the economy.

https://twitter.com/toshiakima/status/1523259874435813376?s=61&t=sBByeWSbsztYGCU9PUQLjg

Anarcho-capitalists who have unleashed unfettered Social Darwinian forces upon society for its betterment, while uttering platitudes about “focused protection”, are predictably those pushing a hard line that only an RCT where we watch subjects die in it is a good study.

These murderous fools fetishise RCTs as the supposed pinnacle of the scientific method. Yet, every day these people trust their lives to engineered devices that were never once tested by RCTs.

https://twitter.com/toshiakima/status/1485086525386014722?s=61&t=sBByeWSbsztYGCU9PUQLjg

The inability to use basic molecular modelling to fully predict the safety/efficacy profile of a drug is the exception in science, not the rule. Our predictive abilities are improving. One day, we will design drugs like engineers design aeroplanes.

https://twitter.com/toshiakima/status/1627184322271920130?s=61&t=sBByeWSbsztYGCU9PUQLjg

I now recall a debate at medical school decades ago during which I heard an ethicist argue that all RCTs were unethical. I thought she was a bit extreme. Now I look back after all this time and see that she was ultimately right. RCTs are a primitive method of last resort.

It's time to reevaluate the validity of RCTs. In the name of progress, medicine must aim to phase out RCTs and become more like engineering. One day, they'll be shocked Fisher's heirs ran studies where people died in the experiment—like Mengele's. amazon.com/Philosophy-Sci…

Postscript. RA Fisher joined forces with Verschauer in the 1950s to minimise the harms of smoking. Correlation does not equal causation, Fisher argued—hence, smoking does not cause lung cancer. nature.com/articles/18259…

If Fisher and Verschauer were around today we know which side they would belong on. They would be welcomed with open arms by the likes of the GBD minimiser mob of meta-analytic garbage regurgitators who are their true heirs. abc.net.au/news/2022-08-3…

Postscript 2. I neglected to emphasise the fact that Nature Heredity @HeredityJournal, which published the shocking apology for RA Fisher above, was co-founded by Fisher in 1947, as pointed out by @RichardEvans36

EDIT: whoops, that is Otmar Freiherr von VERSCHUER (not “Verschauer” with an extra “a” as I mistakenly wrote). en.wikipedia.org/wiki/Otmar_Fre…