Time for #MedMondaysπ THREADπ§΅
1/ ππ§ͺπ¨βπ¬ #Methylphenidate was first synthesized by the chemist Leandro Panizzon in the 1940s. It wasn't until the 1950s that its therapeutic potential was recognized, and it was later introduced as a medication under the brand name #Ritalin.
1/ ππ§ͺπ¨βπ¬ #Methylphenidate was first synthesized by the chemist Leandro Panizzon in the 1940s. It wasn't until the 1950s that its therapeutic potential was recognized, and it was later introduced as a medication under the brand name #Ritalin.
2/ π΄ππ In the early days, methylphenidate was primarily used to treat depression and fatigue. However, its stimulant properties were soon recognized as helpful for treating ADHD and narcolepsy.
3/ π§ π Methylphenidate works by blocking the reuptake of dopamine & norepinephrine, which increases the levels of these neurotransmitters in the brain. This leads to πΌ activity in the prefrontal cortex, which is involved in executive functioning, attention, & decision-making.
4/ ππ₯π€ Ritalin is often compared to the other stimulant for ADHD, Adderall, with both having similar efficacy and similar adverse effects; however, one group of people tend to do better with one family of medication than the other for reasons that are not fully known.
5/ ππ΄π€’ The most common adverse effects of methylphenidate include appetite suppression, insomnia, and anxiety. Some people may also experience gastrointestinal issues or changes in blood pressure or heart rate. In some, irritability and aggression can actually worsen.
6/ πππ There are several different formulations of methylphenidate available, including immediate-release tablets, extended-release capsules, liquid formulations, chewable tablets, and even transdermal patches. Each formulation has its own pros and cons.
7/ π¦πΏπ§πΏπ§πΏ In the 1970s and 1980s, there was a sharp increase in the number of Black children diagnosed with ADHD and prescribed Ritalin. Some critics argued that this was due to racial biases within the healthcare system, which may have led to over-diagnosis and over-treatment.
8/ π¨πΌβπ«π¨πΎβπ«π« Others argued that Ritalin was being used as a way to control and discipline Black children in schools, rather than as a legitimate medical treatment. This led to concerns about the overuse of the medication and its potential long-term effects.
9/ ππ§πΌπ The landmark Multimodal Treatment Study of Children with ADHD (MTA) conducted in 1990s compared the effectiveness of medication, behavioral therapy, &a combination of the two utilized Ritalin and helped shape our understanding of the most effective treatments for ADHD.
π¬π€π What are your thoughts or personal experiences with methylphenidate and its use in treating ADHD and other conditions? Have you experienced any of the side effects or controversies associated with this medication?
ππ¨ββοΈπ Follow along for more #MedMondaysπ!
ππ¨ββοΈπ Follow along for more #MedMondaysπ!
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