Peter Maybarduk Profile picture
Mar 17 11 tweets 9 min read
Things to know before @SenSanders grills Moderna next week:

First, it's called the "NIH-Moderna" vaccine for a reason.

Moderna received more than $12 billion from taxpayers, including $2.1 billion for R&D & roughly $10bn in advance purchase commitments & purchases.

🧵 1/
From 2020-2022, BARDA (at the Dept of Health & Human Services) provided Moderna with $1.7bn to support clinical trials.

@DeanBaker13 @davidalim @Alexruoff

🧵 2/

investors.modernatx.com/financials/sec…
.@NIH gave Moderna $400 million to support preclinical work & clinical trials, bringing the USG R&D contribution to $2.1 billion.

Including AMCs, which de-risked private investment, and procurement, Moderna has received >$12 bn from taxpayers.

🧵 3/

npr.org/transcripts/89…
The vax was developed through a 4-year partnership with @NIH.

But Moderna resisted naming federal scientists co-inventors of the vaccine sequence.

@peoplesvaccine

Thx @RebeccaDRobbins @SherylNYT

🧵 4/

nytimes.com/2021/11/09/us/…
Rather than credit the federal government for its role, Moderna quietly abandoned these patents earlier this month.

🧵 5/

politico.com/newsletters/pr…
.@Public_Citizen revealed this inventorship dispute between NIH & Moderna in 2021, urging NIH to publicly reclaim its foundational role in some of the most important medical tools against the Covid pandemic.

(h/t @zainrizvi)

🧵 6/

int.nyt.com/data/documentt…
Even before SARS-CoV2, public money supported Moderna developing tech later used in NIH-Moderna. @DeptofDefense, @BARDA and NIH each funded Moderna to support vax development for Zika & MERS, which is caused by another kind of coronavirus.

🧵 7/
citizen.org/article/the-pe…
In 2020, @Public_Citizen showed that @moderna_tx & others also relied on a separate technique discovered by federal scientists and academic researchers to stabilize spike proteins and elicit an immune response.

🧵 8/

citizen.org/news/analysis-…
Columbia Law School clinical prof @cmorten2 & students demonstrated Moderna likely infringed the NIH-owned patent.

Morten will testify @HELPCmteDems next Wednesday, speaking to the contributions of federal scientists to the NIH-Moderna vaccine.

🧵9/

dropbox.com/s/1om1v1kagg7j…
Moderna eventually agreed to pay NIH $400 million (plus modest future royalties) for its use of the spike protein stabilization technique.

That's barely 1% of Moderna's global sales.

🧵 10/

nytimes.com/2023/02/23/sci…
NIH-Moderna is the #peoplesvaccine. @moderna_tx should make it available at cost & share mRNA tech w/t world.

Thanks Steve Knievel @PrEP4AllNow @AmeetSarpatwari @DrHussainL @PORTAL_Research @justiceisglobal @gregggonsalves @akapczynski

citizen.org/article/hearin…

🧵 11/11

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More from @Maybarduk

Jun 29, 2020
In an offensive display of hubris and disregard for the public and the pandemic, @GileadSciences has priced at thousands of dollars a drug that should be in the public domain. Gilead’s price is 10x the cost-effective price ($310) suggested by ICER (no mortality benefit) (1/4)
For $1 per day, remdesivir can be manufactured at scale with a reasonable profit. According to ICER, at $310 per course, remdesivir would be cost effective. Gilead has rejected both prices and has yet to show why the price should be higher. (2/4) icer-review.org/announcements/…
Gilead initially developed remdesivir as one of several candidate treatments for hep C and has made tens of billions off its successful hep C drugs. What's relevant now are Gilead’s unpublished costs & the public’s many investments repurposing remdesivir for COVID-19. (3/4)
Read 4 tweets
May 12, 2020
Gilead still wants to control remdesivir. @GileadSciences needs to get used to giving up that control. #Remdesivir should be in the public domain (1/6) @Public_Citizen @MSF_access @uaem @OSFHealth
Today @GileadSciences announced a deal with five other firms to facilitate remdesivir international manufacture and distribution. The more than 70 countries excluded would have to buy remdesivir from Gilead at its monopoly price, or overcome Gilead’s claimed patents. (2/6)
Federal scientists led the team that found that #remdesivir was active against coronaviruses. Public investment supported and continues to support every stage of remdesivir’s development. The public has contributed a minimum of $70.5 million to remdesivir’s development. (3/6)
Read 6 tweets

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