1/ Question for #MMsm hive mind 🙏
For patients with functional high-risk myeloma (e.g., relapse ≤18 mo of 1st-line Tx), any good summary of data for functional high-risk vs high-risk FISH vs both?
Summarizing what I found so far, but I know I must be missing a few studies!
For patients with functional high-risk myeloma (e.g., relapse ≤18 mo of 1st-line Tx), any good summary of data for functional high-risk vs high-risk FISH vs both?
Summarizing what I found so far, but I know I must be missing a few studies!
2/ In KarMMa-2 Cohort A from #ASH22 by @szusmani @DrKrinaPatel et al, 37 patients with #MMsm enrolled in early ide-cel trial for functional high-risk.
Of n=22 with evaluable FISH (I wish it were a little higher), 45% didn't have any high-risk features.
ashpublications.org/blood/article/…
Of n=22 with evaluable FISH (I wish it were a little higher), 45% didn't have any high-risk features.
ashpublications.org/blood/article/…
3/ In #ASH21 RWE #MMsm database analysis by @kansagraMD et al, 1719 pts analyzed inc. hypodiploid as high-risk 🐠
Thanks Ankit for this awesome work! Am I analyzing abstract correctly to say that 73% of functional high-risk pts had standard FISH? 🤯
ashpublications.org/blood/article/…
Thanks Ankit for this awesome work! Am I analyzing abstract correctly to say that 73% of functional high-risk pts had standard FISH? 🤯
ashpublications.org/blood/article/…
4/ In @BloodCancerJnl analysis of @theMMRF CoMMpass data set for "functional super-high-risk" #MMsm patients: relapse ≤12 mo of Tx initiation) *or* ≤MR to induction...
Not much black in bottom half of heat map.
nature.com/articles/s4140…
Any other studies I'm missing?
Not much black in bottom half of heat map.
nature.com/articles/s4140…
Any other studies I'm missing?
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