1. Alternatives to Gain of Function Research
Loss of Function Research
Molecular dynamical modeling of viral proteins
Interactions with inhibitors and receptor
In vitro studies of specific properties required for human adaptation using single proteins
archive.ph/Lzwxz
2. More Alternatives

In vitro studies of genetic interactions between loci in viral proteins using replication-incompetent viruses – epistatic interactions

Sequence database comparisons of genetic properties of human and animal adapted viruses

thebulletin.org/2022/06/gain-o…
3. Ethical Alternatives

"to Experiments with Novel Potential Pandemic Pathogens"

journals.plos.org/plosmedicine/a…
4. The Seven Deadly Sins of....

Biomedical Research

by Laura H. Kahn

gjia.georgetown.edu/2023/03/03/the…Image
5. The latest egregious example in a long list

6. Now is the time to support @BiosafetyNow



@BioSRP
@pricklyresearch
@R_H_Ebright
@mattwridley
@gdemaneuf
@WashburneAlex
@Ayjchan
@alisonannyoung
@BillyBostickson
@nicholsonbaker8
@Bryce_Nickels
@tony_vandongen
@angoffinet
@BiophysicsFL
@ColinDavdButler biosafetynow.orgImage
7. What Needs To Be Made Public

All proposals & progress reports discussing dangerous virus experiments & documents related to the planning of the experiments

Details as to when, where & why such experiments were planned including any review processes involved

Risks & Benefits Image
8. Question of Biowarfare Research

It is now clear (to me) that the US, despite its denials, has pursued an illegal biowarfare program, by outsourcing collection of deadly viruses around the world & making them more virulent & pathogenetic.

We now have all the evidence we need
9. Public Denials, Ongoing Research.

Of course, The US Government and the Scientists involved will never state that they are engaged in biowarfare research, but rather "biodefense" and the noble drive to develop vaccines and prophylactics for deadly viruses & bacterial diseases. Image
10. The New Mantra: "Protecting the War Fighter"

Bio-Defense Now:

56 Suggestions for Immediate Improvements Final Report 85% Biological Defense Project (2005)

US Air Force Counterproliferation Center

airuniversity.af.edu/Portals/10/CSD…Image
11. Recently Highlighted in the #DEFUSE Documents

US Defense Advanced Research Projects Agency (DARPA) program to protect the US “warfighter”
by reverse engineering dangerous SARS-like bat viruses and creating aerosol vaccine sprays for use in bat caves

drasticresearch.org/2021/09/20/158…Image
12. No Need for Resurrection

of more controversial elements of US cold war biowarfare projects (well documented), e.g. aerosolisation of pathogens & their respective delivery programs, as they know exactly how to do all this

Now there is a wider repertoire of offensive weapons Image
Image
13. Extent of Pentagon Biowarfare Program?

Pentagon linked researchers like Lipkin (Mailman) Nichol (Atlanta) Baric (UNC) Bavari, Totura (USAMRIID), Denison, Munster (Rocky Mountain) & DARPA, DTRA, PREDICT Scientists involved could tell us a great deal!

14. Final Point in This Thread

We cannot only point the finger of blame at the US

Russia has continued Soviet work on biological weapons, but I will discuss that in a new thread



Did the Russian program encourage the Pentagon to covertly pursue its own?thebulletin.org/2022/10/the-ru…
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More from @BillyBostickson

Nov 14
🧵Long live the lab-leak hypothesis!

1. The long awaited 293 questions for Dr. Ralph Baric have finally been completed and shared! Long live the quest for truth! You are hereby invited to read the sharpest, most lethal 293-question dossier ever built.

researchgate.net/publication/39…
🧵Long live the quest for truth!

2. When that day finally comes & Baric raises his right hand, every word in there will be waiting for him


@RandPaul @RandPaulReview @TulsiGabbard
@SenJoniErnst @R_H_Ebright @jhas5 @ydeigin @gdemaneuf @mentju4 @emilyakopphsgac.senate.gov/media/reps/cha…
@RandPaul @RandPaulReview @TulsiGabbard @SenJoniErnst @R_H_Ebright @jhas5 @ydeigin @gdemaneuf @mentju4 @emilyakopp 🧵3. Watch the video explainer here

Courtesy of Google Notebook LM

vimeo.com/1136899679
Read 6 tweets
Nov 12
✴️MICROPLASTICS IN YOUR BRAIN?

1. "These tiny fragments were far smaller than cells and even smaller than many viruses. Some were close to the size of DNA strands. Under high magnification, she noticed small hooked shapes with sharp points.
✴️2. OVERLOOKED

"She realized that the plastic in human brains was not only present, but surprisingly small. The fragments were so tiny that common diagnostic tools could not detect them. Pathologists had likely been overlooking them for years."

msn.com/en-us/health/o…
✴️3. NONE WERE FREE

"The two original samples showed a strong link between plastic particles and dementia. As Bearer expanded her work to ten more donated brains, she found plastic in every single one. None were free of synthetic fragments."
Read 23 tweets
Nov 6
🧵1. In the interview with @danaparish

Redfield stresses that the evidence points to lab creation for a reusable, aerosolized vaccine vector, with US complicity in funding/tech.

He says he is fed up with the cover-ups and predicts that full intel release would confirm this.
🧵2. Proof?

Unfortunately, there is no direct proof provided by Redfield in this new interview, but he cites engineering features, early data, and classified information.
🧵3. Summary of Redfield's Statements

(on SARS-CoV-2 Origins & Cover-Up)

He claims SARS-CoV-2 originated from GOF research in a lab and emphasizes a significant US role alongside China.

He views this as a major biosecurity failure with ongoing suppression of transparency.
Read 21 tweets
Oct 30
🧵1. Critique of preprint: SARS-COV-2 like FCS hype

Media article 1

dailymail.co.uk/health/article…

Media article 2

straitstimes.com/world/coronavi…
🧵2. The Authors State:

"Of note, the spike protein of this novel bat coronavirus possesses a functional FCS at the S1/S2 junction with a unique amino acid sequence motif (RDAR) that differs from that found in SARS-CoV-2 (RRAR) by only 1 amino acid."

biorxiv.org/content/10.110…
🧵3. Two fatal flaws: Overreach & Undermine

A. The authors of this study on the BRZ batCoV from Brazil unfortunately overreach themselves when they connect it to SARS-CoV-2 origins.

B. The FCS evidence actually undermines the flawed hypothesis of direct bat to human emergence!
Read 13 tweets
Oct 25
🧵1. Honest question

Did you try to read my pangolin coronavirus report but gave up because it was too long or too complex?

If you didn't see it, link is in next tweet

Help is at hand!

Thanks to Google's pretty amazing "notebook lm"

A video explainer

notebooklm.google.com/notebook/1b843…
🧵2. Just in case..

The massive report is here:

researchgate.net/publication/39…
🧵3. An updated brief explanation on Medium

The Pangolin-Mediated Laboratory Origin of SARS-CoV-2

medium.com/p/the-pangolin…
Read 8 tweets
Oct 4
"The molecular biology capabilities of WIV & the genome assessment are consistent with the hypothesis that SARS-CoV-2 was a lab-engineered virus that was part of a bank of chimeric viruses in Zheng-Li Shi's laboratory at WIV that escaped from containment"

usrtk.org/wp-content/upl…
2. Hypothetical Laboratory Origin of SARS-CoV-2

Between 2017 and 2019, WIV created full-length a infectious clone in pBAC-CMV using an unpublished bat Coronavirus genome as template (BatCoVX)

page 85
3. Hypothesis 3:

Between 2017 and 2019, WIV created chimeric Bat-CoV-X viruses using the pBACCMV-BCOVX backbone and swapping out key cassettes with other bat Coronaviruses (RBD, RBM, etc.) and adding additional features such as a furin cleavage site
Read 15 tweets

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