Thread by @BillyBostickson

1. Alternatives to Gain of Function Research
Loss of Function Research
Molecular dynamical modeling of viral proteins
Interactions with inhibitors and receptor
In vitro studies of specific properties required for human adaptation using single proteins
archive.ph/Lzwxz

2. More Alternatives

In vitro studies of genetic interactions between loci in viral proteins using replication-incompetent viruses – epistatic interactions

Sequence database comparisons of genetic properties of human and animal adapted viruses

thebulletin.org/2022/06/gain-o…

3. Ethical Alternatives

"to Experiments with Novel Potential Pandemic Pathogens"

journals.plos.org/plosmedicine/a…

4. The Seven Deadly Sins of....

Biomedical Research

by Laura H. Kahn

gjia.georgetown.edu/2023/03/03/the…

5. The latest egregious example in a long list

https://twitter.com/R_H_Ebright/status/1641993193104502785

6. Now is the time to support @BiosafetyNow

biosafetynow.org

@BioSRP
@pricklyresearch
@R_H_Ebright
@mattwridley
@gdemaneuf
@WashburneAlex
@Ayjchan
@alisonannyoung
@BillyBostickson
@nicholsonbaker8
@Bryce_Nickels
@tony_vandongen
@angoffinet
@BiophysicsFL
@ColinDavdButler

7. What Needs To Be Made Public

All proposals & progress reports discussing dangerous virus experiments & documents related to the planning of the experiments

Details as to when, where & why such experiments were planned including any review processes involved

Risks & Benefits

8. Question of Biowarfare Research

It is now clear (to me) that the US, despite its denials, has pursued an illegal biowarfare program, by outsourcing collection of deadly viruses around the world & making them more virulent & pathogenetic.

We now have all the evidence we need

9. Public Denials, Ongoing Research.

Of course, The US Government and the Scientists involved will never state that they are engaged in biowarfare research, but rather "biodefense" and the noble drive to develop vaccines and prophylactics for deadly viruses & bacterial diseases.

10. The New Mantra: "Protecting the War Fighter"

Bio-Defense Now:

56 Suggestions for Immediate Improvements Final Report 85% Biological Defense Project (2005)

US Air Force Counterproliferation Center

airuniversity.af.edu/Portals/10/CSD…

11. Recently Highlighted in the #DEFUSE Documents

US Defense Advanced Research Projects Agency (DARPA) program to protect the US “warfighter”
by reverse engineering dangerous SARS-like bat viruses and creating aerosol vaccine sprays for use in bat caves

drasticresearch.org/2021/09/20/158…

12. No Need for Resurrection

of more controversial elements of US cold war biowarfare projects (well documented), e.g. aerosolisation of pathogens & their respective delivery programs, as they know exactly how to do all this

Now there is a wider repertoire of offensive weapons

13. Extent of Pentagon Biowarfare Program?

Pentagon linked researchers like Lipkin (Mailman) Nichol (Atlanta) Baric (UNC) Bavari, Totura (USAMRIID), Denison, Munster (Rocky Mountain) & DARPA, DTRA, PREDICT Scientists involved could tell us a great deal!

https://twitter.com/BillyBostickson/status/1346410189738577923

14. Final Point in This Thread

We cannot only point the finger of blame at the US

Russia has continued Soviet work on biological weapons, but I will discuss that in a new thread

thebulletin.org/2022/10/the-ru…

Did the Russian program encourage the Pentagon to covertly pursue its own?