1. Alternatives to Gain of Function Research
Loss of Function Research
Molecular dynamical modeling of viral proteins
Interactions with inhibitors and receptor
In vitro studies of specific properties required for human adaptation using single proteins
archive.ph/Lzwxz
2. More Alternatives

In vitro studies of genetic interactions between loci in viral proteins using replication-incompetent viruses – epistatic interactions

Sequence database comparisons of genetic properties of human and animal adapted viruses

thebulletin.org/2022/06/gain-o…
3. Ethical Alternatives

"to Experiments with Novel Potential Pandemic Pathogens"

journals.plos.org/plosmedicine/a…
4. The Seven Deadly Sins of....

Biomedical Research

by Laura H. Kahn

gjia.georgetown.edu/2023/03/03/the…Image
5. The latest egregious example in a long list

6. Now is the time to support @BiosafetyNow



@BioSRP
@pricklyresearch
@R_H_Ebright
@mattwridley
@gdemaneuf
@WashburneAlex
@Ayjchan
@alisonannyoung
@BillyBostickson
@nicholsonbaker8
@Bryce_Nickels
@tony_vandongen
@angoffinet
@BiophysicsFL
@ColinDavdButler biosafetynow.orgImage
7. What Needs To Be Made Public

All proposals & progress reports discussing dangerous virus experiments & documents related to the planning of the experiments

Details as to when, where & why such experiments were planned including any review processes involved

Risks & Benefits Image
8. Question of Biowarfare Research

It is now clear (to me) that the US, despite its denials, has pursued an illegal biowarfare program, by outsourcing collection of deadly viruses around the world & making them more virulent & pathogenetic.

We now have all the evidence we need
9. Public Denials, Ongoing Research.

Of course, The US Government and the Scientists involved will never state that they are engaged in biowarfare research, but rather "biodefense" and the noble drive to develop vaccines and prophylactics for deadly viruses & bacterial diseases. Image
10. The New Mantra: "Protecting the War Fighter"

Bio-Defense Now:

56 Suggestions for Immediate Improvements Final Report 85% Biological Defense Project (2005)

US Air Force Counterproliferation Center

airuniversity.af.edu/Portals/10/CSD…Image
11. Recently Highlighted in the #DEFUSE Documents

US Defense Advanced Research Projects Agency (DARPA) program to protect the US “warfighter”
by reverse engineering dangerous SARS-like bat viruses and creating aerosol vaccine sprays for use in bat caves

drasticresearch.org/2021/09/20/158…Image
12. No Need for Resurrection

of more controversial elements of US cold war biowarfare projects (well documented), e.g. aerosolisation of pathogens & their respective delivery programs, as they know exactly how to do all this

Now there is a wider repertoire of offensive weapons Image
Image
13. Extent of Pentagon Biowarfare Program?

Pentagon linked researchers like Lipkin (Mailman) Nichol (Atlanta) Baric (UNC) Bavari, Totura (USAMRIID), Denison, Munster (Rocky Mountain) & DARPA, DTRA, PREDICT Scientists involved could tell us a great deal!

14. Final Point in This Thread

We cannot only point the finger of blame at the US

Russia has continued Soviet work on biological weapons, but I will discuss that in a new thread



Did the Russian program encourage the Pentagon to covertly pursue its own?thebulletin.org/2022/10/the-ru…
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More from @BillyBostickson

Jun 3
1. Remote truck drone swarm bombings are here to stay!

The techniques will be improved and nowhere will be safe unless underground.

Questions to consider:

How many panel vans, transit vans and small trucks are there in a big city at any one time?
2. This is a revolution in sabotage tactics



Welcome to the future of air bases!

Without concrete and earth roofed revetments, aircraft are sitting ducks.kyivpost.com/post/53749
3. The "good old days"

"clandestine antiaircraft devices using gallium metal pencils which when applied to aircraft results In destruction due to stress failure at the point of application"

osti.gov/opennet/servle…

Use & Effectiveness of Sabotage (1987)

apps.dtic.mil/sti/tr/pdf/ADA…
Read 15 tweets
May 29
As we edge faster and faster into the future, the future

Why not travel back in time, a mere one hundred years?

Thanks to the @internetarchive

Take a moment to digest the news and advertisements found in the Hong Kong Daily Press 28th of May 1925

archive.org/details/NPDP19…
Some stories!

GREAT REVOLT SCHEME. SECRET PLANS OF THE THIRD INTERNATIONAL. BOLSHEVISING BULGARIA. A BALKAN FRONT. SPENDTHRIFT MURDERER. SPENDS AMILLION FRANCS IN FOURTEEN DAYS. MENUS OF LONDON'S ZOO. MR. CHURCHILL'S BUDGET. HAKKAS AND HOKLOS. PITCHED BATTLE AT PING CHAU.
More stories!

CANTON SITUATION. SPORT IN THE FAR EAST. GERMAN DISARMAMENT. BRITISH SILK DUTIES. COTTON SPINNERS. WORKING WEEK DISPUTE NOT YET SETTLED. FATE OF AMUNDSEN. MR. HAMMER IS MAKING PLANS FOR RESCUE. THE SOFIA OUTRAGE. POSITIONS FOR TROTZKY. THE EPSOM DERBY.
Read 34 tweets
May 22
🧵1. Another Modest Proposal

This time for the Pangolin’s Noble Sacrifice!

In this enlightened year of our Lord 2025 I, a humble observer of mankind’s ceaseless quest for health, find myself much struck by the ingenious practices of the Orient..
🧵2. A Scaly Panacea

...where the pangolin, that scaly denizen of subtropical climes, hath been elevated to a panacea most wondrous.

The Baicao Chinese Medicine compendium, a veritable gospel of herbal wisdom, doth proclaim the virtues of this creature’s scales...
🧵3. Humanity's Salvation?

...harvested with a diligence that would shame the most ardent of alchemists.

I propose, therefore, a modest scheme to amplify this noble tradition, ensuring that the pangolin’s sacrifice might serve the greater good of humanity.
Read 16 tweets
May 21
🧵🗞️The International News

A Convulsive Horizon of No Escape

Clang! Bar, far, scar, star.

Take the swarming headlines, shred them,

South Korea’s soy sauce grand master stirs

Books that don’t exist, AI’s fevered brew.

War without purpose, war crimes bite,
🧵🗞️ Clang! Crimes, limes, slimes!

EU’s chocolate crisis, cocoa beans scream!

Climate breakdown bites the fields.

The moment that changed me

a boulangerie revelation melting into Vindolanda’s stone relief

But the man in the navy suit and tie,

chokes on known unknowns.
🧵🗞️ Clang! Rice, nice, vice, dice!

Japanese minister’s rice is free, free, glee, spree,

As Trump’s tariffs tangle with toilet roll wedding lists.

No escape. The hour will no longer be ours.

Clang! Dome, home, foam, roam!
Read 38 tweets
May 16
Some insights into our DRASTIC investigation

1. What appears wasteful research to you in the present may be of great value to you or others in the future, if it is given the time to develop to its logical end.

Don’t judge the usefulness of your findings too quickly!
2. What appears wasteful or a dead end to you..

May be of immense value to somebody else!

Don’t judge the usefulness:

1. Of other people’s findings based only on your own assessment of them.

2. Of your own findings based only on your own current assessment of them either.
3. What appears wasteful and a dead end to you..

A. May be the raw stuff that new hypotheses and new research directions are born from.

B. Don’t judge the usefulness of your "investigations" until you have given them enough time to surprise you.
Read 15 tweets
May 13
🧵Holmes Studies "Lab Leak"🤔

1⃣ WIV

-Deliberate release of bioweapon
-Accidental release of bioweapon in development
-Lab accident during genetic engineering
-Lab accident during cell culture
-Lab accident during vaccine development
-Accidental infection that no one knew about
2⃣ WCDC

• Lab worker infected during field animal sampling
• Accident during experimental work
• Accident from exposure to infected waste
• Accident during move to new location
• WCDC gave bat samples to the WIV
3⃣ Virus engineering

•Engineered from RaTG13
•Engineered from pool of bat viruses (Laos)
•Engineered from secret database of bat viruses
•Engineered at UNC & shipped to the WIV
•Engineered hybrid of bat & pangolin viruses🐵
•Synthetic infectious clone engineered in vitro
Read 8 tweets

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