2/ 🩸Few reasons to withhold #OAC, even in frail, older adults
🩸Across spectrum of #bleeding risk in AF, #stroke risk is higher
🩸#DOACs preferred over warfarin in #nonvalvular#AF
3/ 🩸Most #DOACs safe in #CKD, some require dose adjustment
🩸Dabigatran contraindicated in eGFR<30
🩸Limited RCT evidence in #Hemodialysis
Treatment of #LVThrombus
🩸#DOACs a reasonable option vs #warfarin
🩸#OAC duration depends on context & persistence of protruding LV thrombus
🩸Persistent laminar thrombus doesnt require longterm anticoagulation
🩸No evidence to support #OAC in primary prev of LV thrombus 4/
• • •
Missing some Tweet in this thread? You can try to
force a refresh
Proud to have led this #clusterRCT, presented @ESCCardio's #LBCT session & published today in @JAMA_current. Among 2495 adults (50% women) hospitalized for #HF, a transitional care model implemented in our publiclyfunded system did not ⬇️time to comp readmission/ED visit/death.
There was a significant improvement in the patient-reported outcomes of #discharge-preparedness, #qualityofcaretransition, and #QOL. However, there was no improvement in #QALY. The #PROs were not adjusted for multiplicity, but we will do post-hoc exploratory analysis.