👨‍⚕️Very nice session on issues of complicated UTIs by Dr. Aurelien Dinh. #ECCMID2023
- It's believed that cUTI is more difficult to treat
- Maybe higher rate of resistance
- Need higher dosage or prolonged treatment? ImageImage
Modern definitions of cUTIs... #ECCMID2023 Image
Does "complicated" definition apply to all kinds of UTIs? Uncomplicated pyelonephritis?? 🤨 #ECCMID2023 Image
Guideline recommendations for uncomplicated cystitis. EAU has recommendations for uncomplicated UTI in men! #ECCMID2023 Image
Guideline recommendations for uncomplicated pyelonephritis... 🤨 #ECCMID2023 Image
Guideline recommendations for catheter-associated UTI... #ECCMID2023 Image
7 days of treatment is effective in afebrile man with UTI. #ECCMID2023 Image
How about febrile men with UTI?
- Similar clinical success with 7 days of treatment.
- Is microbiological success relevant to clinical practice?
#ECCMID2023 Image
Patients with neurogenic bladder:
- Afebrile can be treated similar to uncomplicated UTIs
- Febrile requires more caution, similar to complicated UTIs
#ECCMID2023 Image
Conclusions:
#ECCMID2023 Image

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More from @LordAlirezaF

Oct 14, 2023
📃Upcoming Guidelines Spoilers #IDWeek2023
First-ever IDSA guidelines for complicated Urinary Tract Infection (cUTI) #UTI Image
📃IDSA guidelines for cUTI #IDWeek2023 #UTI
- New definition of cUTI
– Includes all febrile UTI, pyelo, CAUTI, bacteremic UTI Image
📃IDSA guidelines for cUTI #IDWeek2023 #UTI
- Selection of empiric antibiotic therapy for cUTI
– Four-step process: Review
(1) severity of illness,
(2) risk factors for resistant organisms,
(3) patient factors, and
(4) antibiogram (only if septic)
Image
Image
Read 12 tweets
Apr 15, 2023
🛌Fantastic presentation by Dr. Isabel Spriet on #antifungal dosing, which included several patient case discussions! #ECCMID2023
- Major clinical uses of antifungals
- Focus is on invasive fungal infections Image
Standard dosing of antifungals are based on patient PK, fungal pathogen PD, and ideal PK-PD targets... #ECCMID2023 Image
Translational research model for antifungal drug development involves pre-clinical PK-PD target determination followed by clinical trials... #ECCMID2023 Image
Read 11 tweets

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