👨⚕️Very nice session on issues of complicated UTIs by Dr. Aurelien Dinh. #ECCMID2023
- It's believed that cUTI is more difficult to treat
- Maybe higher rate of resistance
- Need higher dosage or prolonged treatment?
Does "complicated" definition apply to all kinds of UTIs? Uncomplicated pyelonephritis?? 🤨 #ECCMID2023
Guideline recommendations for uncomplicated cystitis. EAU has recommendations for uncomplicated UTI in men! #ECCMID2023
Guideline recommendations for uncomplicated pyelonephritis... 🤨 #ECCMID2023
Guideline recommendations for catheter-associated UTI... #ECCMID2023
7 days of treatment is effective in afebrile man with UTI. #ECCMID2023
How about febrile men with UTI?
- Similar clinical success with 7 days of treatment.
- Is microbiological success relevant to clinical practice? #ECCMID2023
Patients with neurogenic bladder:
- Afebrile can be treated similar to uncomplicated UTIs
- Febrile requires more caution, similar to complicated UTIs #ECCMID2023
🛌Fantastic presentation by Dr. Isabel Spriet on #antifungal dosing, which included several patient case discussions! #ECCMID2023
- Major clinical uses of antifungals
- Focus is on invasive fungal infections
Standard dosing of antifungals are based on patient PK, fungal pathogen PD, and ideal PK-PD targets... #ECCMID2023
Translational research model for antifungal drug development involves pre-clinical PK-PD target determination followed by clinical trials... #ECCMID2023