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☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 Profile picture
@DrJackKruse
Apr 21, 2023 • 7 tweets • 4 min read • Read on X
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1. You need to remind people that science is the process that takes us from confusion to understanding. In this sense science is the communication path man should be using to study how nature shapes us. ImageImage
2. We have to remind ourselves that the path is fallible because of the process of nature and the nature of man. Man always creates errors and often he fails to understand why his methodologies can create many scientific fallacies believed to be fact. Much of what man has learned… twitter.com/i/web/status/1… Image
3. This occurs because Mother Nature’s hand is capable of erasing while she simultaneously write’s more wisdom that builds things around us. You begin to realize in every experiment and theory there’s no such thing as a complete lie or complete truth. There’s always some truth in… twitter.com/i/web/status/1… Image
4. Realizing what was once believed to be true, but no longer is true, is what creates man’s wisdom. Everyone starts out the same way in life. Shit at what they do. You learn, and you improve, and you make tiny little changes every day to become better than you were yesterday. Image
5. That’s how every scientist, physician, artist, writer, founder, lover, and designer built their careers and armamentarium. So when you look back at the work you did in this life, you can’t feel ashamed of your work. Celebrate your connection to it, because it proves your… twitter.com/i/web/status/1… Image
6. Be passionate about yourself and your life. It is you and you must own it. Enthusiasm can help you find the new doors, but it takes passion to open them. If you have a strong purpose in life, you don't have to be pushed. Your passion will drive you there. #Sunrise… twitter.com/i/web/status/1… Image
7. Many people arguing about diet, carbs or thyroid levels are missing the greatest points that biology is teaching us,  because they do not realize the perspective of how our metabolisms have always been set, by circadian cycles and not much else.  In fact, the… twitter.com/i/web/status/1…

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More from @DrJackKruse

☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 Profile picture
Mar 14
My view is that it is all quantized to electromagnetism, the structure of elements on the periodic table, and how they vary their physics as the environment changes on Earth. This scales to the mathematics of size and shape which is a thermodynamic idea and ultimate it ends up with the idea linking to Platonic solids. I have a non Darwinian approach.

My non-Darwinian take could argue that climate tensions (cold, dry) imposed thermodynamic constraints—say, energy budgets forcing molecular efficiency—that “snapped” haplotypes into new forms, bypassing random mutation. Think of it like a system finding a lower energy state, not trial-and-error survival.

But Darwin’s model still holds up because there is a memory of the past in cells: ancient DNA shows gradual haplotype shifts in humans (e.g., lactose tolerance in northern pastoralists), not sudden jumps.

Quantum mechanics might tweak mutation rates (e.g., UV damage to DNA), but it’s not replacing selection. It does argue that gradualism is not the key. Timing and thermodynamics are the key.

Why do I run with this anti-Darwin angle in my work? Consider the Cambrian and K-T suggest environmental jolts—like climate swings or impacts—could trigger rapid, physics-driven reorganizations.

Maybe this answer I am giving you sees human migration similarly: a climate shock flipping genetic switches. It’s intriguing, speculative, view point of decentralized biology that still leans on selection to explain haplotype patterns, even if physics sets the thermodynamic stage of adaptation.
2. My view is that Darwin was wrong to focus on natural selection as the primary driver of evolution, missing the deeper role of quantum mechanics and thermodynamics.
I highlighted:

Hemoglobin Variability: Birds (e.g., Arctic tern) and reptiles (e.g., alligators) show extreme hemoglobin adaptations—high-altitude flight versus underwater hibernation—that Darwinian gradualism can’t explain. I suggested these reflect quantum-driven leaps tied to environmental conditions, not slow selection.

Conditions of Existence: Darwin emphasized this over natural selection but couldn’t explain it. I equate it to epigenetics, driven by quantum field physics (e.g., light and energy interactions), not random mutation.

Quantum Thermodynamics: Evolution operates via mass equivalence (Einstein’s E=mc²), where energy quanta shape biological forms. Morphology (Darwin’s focus) is secondary to these physics-based mechanisms.

Critique of Neo-Darwinism: Figures like Dawkins cling to natural selection without a molecular mechanism, ignoring Feynman’s call for precision and Einstein’s insights into energy. Genes are not deterministic.

Light as Driver: Information in light (e.g., electromagnetic forces) controls life’s direction, a quantum process Darwin couldn’t fathom in his era.

My view is that evolution isn’t a gradual, selection-driven process but a series of quantum jumps triggered by environmental energy states—think thermodynamics and light, not survival of the fittest. It is a survival of the wisest in information processing.

I wrote this 19 years ago and posted it 111 years ago on the topic and my opinion still has not changed.

jackkruse.com/osf-3-darwin-w…
3. You asked me about haplotypes evolving as humans migrated from tropical to colder, drier climates.

Darwin’s lens would say: random mutations in genes (e.g., for skin pigmentation or metabolism) were selected for in harsher northern conditions, shaping haplotype frequencies over generations.

The original answer I gave leaned on electromagnetism and Platonic solids, suggesting a physics-first view where environmental changes dictate form thermodynamically. Consider POMc gene. On our nearest cousins it was on a different chromosome than it is on humans and primates use melanin more on their exterior than than interior. Melanin is far more important on our insides because it gaves us more photo-bioelectric computation to craft our cells to become more complex = building the frontal lobes for example.Image
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Read 23 tweets
☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 Profile picture
Mar 10
Remember when Danny Jones asked me at the end of our first podcast why all the young males he knew were taking testosterone and wanted to know if this was somehow related to the MKULTRA story, and I smiled?

Well, it is.

The Great Oxidation Event, what I like to call the Oxygen Holocaust due to nnEMF toxicity, is going on in every skull on Earth now due to nnEMF and blue ubiquitous use.

Suppose you understand what I have laid out on my blogs over 20 years. In that case, all chronic diseases are photo-bioelectrical electrocution of the inside of a cell of the anterior pituitary and the gonads by cell phones in the pocket next to said jewels is ongoing.

Why? Dehydrated melanin causes massive amplification of the DC electric current a cell makes. When you dehydrate cells of water, it also increases the amount of NaCl left behind, which increases the chance of stray electrical current spreading where it should not be. Your anterior pituitary and your balls. This is why those affiliated with DARPA and the FDA just did this.

Centralized MDs will run to write Rx for BigHarma. My tribe knows better. If you knew how to ask better questions, you'd discover that the ionosphere is a giant RF microwave device that dehydrates you daily. @JonesDannyImage
2. The blue light man has made via the MKULTRA experiment, which is now global, will destroy this heme cytochrome by vitamin A liberation. NO = Nitric oxide is also destroyed.  Recall that NO controls the behavior of our stem cell depots.  This is why every snake oil salesman now sells lemmings stem cell injections.  Moreover,  I hope you remember the lesson I delivered in Patreon: this information carried in NO concentrations is also supplied to the POMC/melanin complex in cells when hemoglobin is in a specific oxidation state.  Melanin has to be well-hydrated to optimize any hormone panel at the brain and gonad level.  Right now, nnEMF is causing a TBI in everyone's anterior and posterior pituitary (vasopressin) while causing mtDNA mutations to diminish DDW production at cytochrome c anther heme-based protein.

380 nm light also controls the regenerative state of your hormone panel. This was a tremendous optical arrangement for the survival of mammals 65 million years ago. Still, it is now a big problem when you realize that we are in the Great Oxygen Holocaust due to nnEMF and what dehydration of the heme-containing cytochrome P450scc is designed to do in modern mammals' insides under the power of ALAN, where POMC is boss.

This enzyme carries out the so-called side chain cleavage reaction, consuming cholesterol to produce pregnenolone, the precursor of cortisol, and all other steroids. If melanin is not well hydrated, this cleavage fails, and you get pregnenolone steal syndrome.  This is why males are losing testosterone at record rates and why females' sex steroid hormones are being demolished too.

Glucocorticoid synthesis is tightly regulated at the level of cholesterol metabolism, which responds to ACTH stimulation over minutes and ceases equally quickly when this hormone is removed. All require well-hydrated melanin sheets to make Becker's regenerative current.  Remarkably, this dynamic process is modulated under most circumstances not by control of the intrinsic enzymatic activity of P450scc, but rather by substrate availability. If that substrate is not there because you're missing Becker's current you are screwed.  For this reason, cholesterol transport within the mitochondrion has emerged IN ALL MAMMALS as the key control point for steroidogenesis.

Epigenetic light signals control all your hormone panels.  MKULTRA found this out in 1964, and the government has weaponized it to put in screen technology to use against you since screens replaced paper.  It was confirmed in Neil Armstrong's testosterone catastrophe when he returned from the Moon.  Not only did he have pseudotumor cerebri, but he also had head optic nerve swelling that linked his nnEMF exposure to his acute rapid loss of pituitary function.

DARPA took the lesson and added to another silo they developed in California where screens were moved from green analogy signals to blue lit.  This is why books are being cancelled for screens, and all screens are now all blue-lit. It is why Obama and Biden are burying incandescent bulbs from markets—the implications of the Danny Jones podcast are on display in this very post. Few will make the connections. Thankfully, I am interested in those who will.

Science is a tough place not to get canceled these days.Image
3. All will be screwed during this event. Image
Read 6 tweets
☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 Profile picture
Mar 10
How did we get creativity? Neanderthals migrated North got to 51st latitude froze started wearing animal skins and used fire inside caves and their brains shrunk as a result. As they shrunk due to dehydrated melanin sheets, melanin becomes dopamine. The dopamine built up and we got art culture and DaVinci.Image
2. Note how melanin degrades on the slide on the top line. It degrades into dopamine, other amines, and L-DOPA. When you undergo a TBI, as the Neanderthals did by going too far up on the planet, it gets cold, and you need animal skins and fire to keep you warm. Why? Neanderthals did not have uncoupled haplotypes yet. That is a human innovation to high-latitude living. As a result, they flood their shrinking brain with more dopamine than they should have had. Voila = You eventually get Michealangelo, DaVinci, and Rembrandt.Image
3. Look at the picture. Image
Read 9 tweets
☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 Profile picture
Mar 9
The Birkeland currents in space directly scale to the bioelectric currents and electric resistance on our membranes in a cell, so yes this post is spot on. Image
2. As Chris points out, Birkeland Currents are observed in Earth’s magnetosphere (e.g., 10⁵-10⁶ amperes), these currents are driven by magnetic reconnection, a process scalable to cellular ion channels. No direct studies link them to bioelectric currents yet but maybe @MitoPsychoBio or Levin will consider testing this as Becker did with Brown in the UK, but fractal models (e.g., 2022 Physical Review Letters) suggest universal energy flow principles because these are laws of nature not subject to belief.

Space Weather and Health: A 2023 study in Scientific Reports correlated geomagnetic storms with increased hospital admissions for mental health issues, supporting the bipolar disorder claim. Anthropogenic nnEMF (e.g., 5G at 3.5 GHz) is understudied, with the WHO citing insufficient evidence of harm, possibly due to industry influence.

Melanin and Bioelectricity: Becker’s work showed melanin conducts currents (e.g., 10⁻⁶ A/cm² in salamanders), disrupted by dehydration, aligning with my ideas here. Sunlight’s role in melanin hydration lacks large-scale data but fits the physics that underpins chronobiological evidence.Image
3. Implications and Decentralized Synthesis

Resistance and Energy Flow: Chris's post’s focused on resistance scaling from space connecting to cells mirrors Picard/Levin ideas in their éR framework, where mitochondrial efficiency (steps 7-9 in pic) depends on bioelectric balance, disrupted by blue light, nnEMF, and deuterium.

Therapeutic Potential: Methylene Blue’s stabilization of éR when the IMM has low delta psi, combined with sunlight and grounding, mitigate these effects, enhancing regeneration currents and reducing in many diseases like neurodegeneration risks in CTE or MS.

Societal Impact: My link to cognitive decline from poor light choices extends to Chris's post cosmic-biological narrative, suggesting environmental factors shape societal decision-making. This is certainly true in stock markets and in discussions on social media where chaos exists.

Critical View: The centralized establishment’s resistance to these ideas may stem from a lack of biophysical mechanistic studies and a preference for molecular over bioelectric models. Interdisciplinary research is needed to validate this scaling hypothesis. This is where Picard and Levin have to put their big boy pants on and get to physics. My world ;).Image
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Read 13 tweets
☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 Profile picture
Mar 9
1. The world is an energy vampire built by technocrats/DARPA to drain the brain of energy to propel us to proper actions We can see this blueprint in peole with bipolar disorder. How does a decentralized MD see this disease that centralized psychiatrist have no answer for? Image
2. Bipolar disorder (BD) is a chronic and common psychiatric pathology, which can be particularly disabling. The disease has a global prevalence rate of 1–4%, begins at an early age, i.e. predominantly between 15 and 25 years old, and persists throughout the life of patients. BD is characterized by a recurrence of mood depressive episodes (pathological decrease in mood and energy), hypomanic or manic episodes (pathological increase in mood and energy), or even mixed episodes (simultaneous presence of depressive and manic symptoms).

These thymic episodes are interspersed with phases of clinical remission, known as “euthymic” episodes. The disease is associated with a high morbidity and mortality rate and due to the significant functional impact it induces, including during euthymic periods, BD is the cause of poor quality of life and is one of the ten most disabling diseases according to the World Health Organization.

The diagnosis of BD is mainly clinical and can be supported using scales or questionnaires. The diagnostic delay is estimated at around 10 years. This delay is clearly related to the heterogeneity of the clinical expression of the disease. The study of the literature shows that this delay in treatment seriously affects the prognosis, particularly on the functional level, and constitutes a major public health problem. In addition, there are no biomarkers, easily usable in current practice, to help the clinical decision for the diagnosis or for predicting the course or prognosis of the disease.Image
3. Sleep disturbances and sleep/wake rhythms are major in BD. These disturbances are observed during the different phases of the disease and are major symptoms of mood episodes and belong to the diagnostic criteria for depression, hypomania, and mania. In addition, these anomalies are also found during the euthymic phases of this disease. Indeed, patients suffering from BD would be more likely to present a more evening chronotype and a more languid and rigid circadian type than healthy subjects as well as a decrease in the efficiency of their sleep, an increase in sleep duration, an increased sleep latency and a prolongation of the duration of awakenings after the onset of sleep. These disturbances in sleep and wake/sleep rhythms are associated, among other things, with more frequent relapses, an alteration in the quality of life, and cognitive disorders.

Additionally, neurocognitive deficits are frequently associated with BD. Most typical deteriorations found are impairment of episodic verbal memory, executive functions, processing speed, and sustained attention. These troubles can be present during mood episodes but also in around 30% of patients during euthymic phases. Cognitive deficits of patients with BD have a direct impact on their psychosocial functioning, on the risk of relapse, on treatment adherence, or even on their ability to insight. Their early detection associated with the identification of prognostic and predictive biomarkers of the response to cognitive and functional remediation tools is essential in order to be able to offer early and appropriate treatment.

Now listen to what I said about consciousness here before going further. It occurs very early in the podcast:
youtube.com/watch?v=zCGnMY…
Read 37 tweets
☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 Profile picture
Mar 8
Know your history because you do not. When LDL rises it a symptom of someone who needs to go into the sun more to lower the LDL by converting said cholesterol to Vitamin D to optimize your immune function. It never requires a drug or diet to repair. PAD is caused by ALAN or a lack of sunlight.

Peripheral Arterial Disease = PAD = Atherosclerosis = a lack of UV light or too much ALAN or both.

UVB light improves systemic inflammatory diseases by modulating the adaptive immune system. This is huge for autoimmune conditions and chronic inflammatory processes found in all chronic diseases. It shows you that the paradigm of centralized dermatologists, lipidologists, and cardiologists is dead wrong.

CITES
ahajournals.org/doi/10.1161/AT…Image
2. Statins are mitochondrial toxins because of their effect on CoEnzQ10 and cytochrome C oxidase. There are many ways in which they increase coronary artery calcification. One way is depletion of NO due to poor light and Vitamin K2 production from the gut, another is lack of sun to control calcium flows, and another is direct arterial melanopsin damage liberating Vitamin A to cause intimal damage and a loss of arterial NO.

Sufficient production of vital biochemicals such as Geranylgeraniol (GGPP) is required to maintain endotoxin tolerance in macrophages in our arteries once the damage occurs. Macrophages are the hallmarks of CVD/Atherosclerosis, contributing to plaque development, inflammation, and the promotion of thrombosis. Geranylgeraniol is downstream of Mevalonate in the cholesterol synthesis pathway, and GGPP synthesis is inhibited by Statins, as is CoQ10 and K2. Vitamin K2 is the cofactor for matrix Gla-protein activation, which PROTECTS arteries from calcification.

Statin use is independently associated with increased calcification in patients, & using an animal model of hypercholesterolemia, we present a molecular mechanism whereby statins promote the calcification of atherosclerotic plaque. ahajournals.org/doi/10.1161/AT…
3. This is why people with high LDLs tend to have low Vitamin D's, high BP, PAD, and glaucoma. All link to a lack of UV light and too much ALAN. Image
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