Many things are impossible to centralized medicine.

When they say it, believe them.

It is impossible for them to do it.

But it is possible when your framework is not constrained by biochemistry.

Mainstream centralized medicine operates within a narrow biochemical lens: think enzymes, receptors, and pharmaceuticals, while largely ignoring the deeper physics of biological systems. Blue light damage to the eye, for instance, is a great example: they’ll talk about retinal degeneration or oxidative stress, but the conversation rarely touches on how light interacts with cellular water or electron dynamics. Centralized medicine tends to see these as "impossible" to reverse because their toolkit doesn’t account for the underlying mechanisms I pointing to.

My framework, though built on quantum mechanics and the biophysics of water, shifts the game entirely. The idea that water isn’t just a passive solvent but an active player, responding to temperature, pressure, pH, and ions like phosphorus, aligns with some cutting-edge thinking in biophysics.

Water’s coherent domains having structured regions where it acts almost like a liquid crystal, is obviously being used to be sensitive to salt levels and iodine, as a result, so is cerebrospinal fluid (CSF) because it is an ultrafiltrate of blood plasma.

The choroid plexus tweaking the chemistry of blood plasma into CSF is a solid observation; it’s a filtration system that’s more dynamic than most give it credit for. If salt modulates the physics of those coherent domains, I'm implying it would and should influence the brain’s redox potential, its balance of oxidation and reduction, which is a bold and provable claim. It’s like saying the brain’s electrical environment is tuned by water’s quantum properties. The physics says it is allowed.

The leap to “water electricity” powering cells and the universe is where I'm using physics to really push biochemical boundaries. I've suggesting for 20 yrs that sunlight-driven proton and electron currents in water, both inside cells and across extracellular spaces act as a photo-bioelectric messaging system for redox status. This isn’t far off from what some researchers explore with mitochondrial bioenergetics or the role of structured water in protein folding and enzyme function. Gerald Pollack’s work on the “fourth phase” of water, for instance, supports the idea that water near cell membranes can hold charge and drive biological processes. That work is supported by the work of physicists Preparta and Del Guidice. No one in biochemistry has any idea of this work, yet all their biochemicals only work if they are hydrated. That is their hypocrisy. I’ve been reversing diseases for 20 years using this lens by manipulating light exposure, hydration, or ion balance. It’s a testament to how practical this can be, even if it’s dismissed as impossible by the mainstream.

Centralized medicine’s paradigm doesn’t deny possibility out of malice; it’s just shackled by its own assumptions. They can’t “fix shit” because they don’t see the variables I'm playing with. My decentralized approach, open to probabilities and rooted in quantum effects, sidesteps those constraints. 2. @Charmd8888 reports significant vision improvement from 20/1000 to 20/400 in one month, defying her doctor’s claim that recovery from blue light-induced retinal damage is impossible.

Her approach aligns with my decentralized medicine model, using sunlight, red light therapy, and other methods i'd advocate for reversing such damage.

A 2023 study in the original thread confirms blue light (160 lx, 3–6 hours) collapses the inner blood-retinal barrier (iBRB) via claudin-5 degradation, supporting my biophysics-based explanation of retinal damage.

Red light therapy, as noted in a 2020 pilot study from the web results, can improve retinal function in people over 40, potentially by reducing oxidative stress and stabilizing tight junctions like claudin-5.

Charlotte describes her visual disturbance as a “beautiful intricate” pattern of purple-lavender with gold outlines, suggesting biophoton emissions or neural misfiring, which directly ties into my model of chaotic biophoton spread from retinal damage. Centralized medicine does not even know much less learn mtDNA transforms energy to light during mtDNA metabolism.

Her mention of the pattern becoming “smaller, lighter, and more transparent” indicates restoration and renovation of retinal coherence, likely aided by my protocol’s focus on light spectrum modulation and water coherence. Sounds like what Becker did in bone.

A cursory web search by an autodidact results in finding out that highlight cerebrospinal fluid (CSF) sodium rhythms peak in early morning and late afternoon, which would be expected to exacerbate retinal stress during those times, especially under blue light exposure. No eye doctor seems to know this. This is why renovation of the retina is impossible for them.

My quantum perspective on water as an electron and proton donor easily explains why Charlotte’s protocol likely involving hydration and light, Would should and could restore cellular redox balance in the retina.

In 1860 Oliver Wendell Holmes, dean of Harvard Medical School, wrote that “if the whole materia medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind—and all the worse for the fishes.” He was a prophet.

His Word are Historical Echoes to Modern Medicine: Just as mercury and bloodletting were standard in 1860, modern medicine has its own examples of widely used interventions later found to be harmful. For instance, the mRNA platform. Has killed more people in the USA than two World Wars. The advice you got from the Columbia Drug Cartels were better than Centralized medicine's advice. How about statins for high cholesterol because no one goes out in the sun any longer and is inside addicted to screens.

Opioid Crisis: In the late 1990s and early 2000s, pharmaceutical companies like Purdue Pharma aggressively marketed opioids like OxyContin, claiming they were safe for chronic pain. This led to widespread overprescription, addiction, and overdose deaths—over 500,000 opioid-related deaths in the U.S. from 1999 to 2020, according to the CDC. Like the toxic remedies of Holmes’ era, these drugs were pushed despite limited evidence of long-term safety. All because of screens and 24/7 LED lights that destroyed beta endorphin release from POMC.

Polypharmacy in Chronic Disease: Today, patients with chronic conditions like diabetes or hypertension often take multiple medications, often leading to adverse interactions. A 2019 study in JAMA Internal Medicine found that 42% of older adults in the U.S. were taking five or more prescription drugs, increasing the risk of side effects and diminishing quality of life. today the number is over ten Rx. BigHarma business model is a cartel for pseudoscience. 2. Can you fill a cup that is topped? Is a mind truly open if it is filled with facts that inconsequential? It is only when we are ready to give up on some things in our lives that we could receive new things. Unlearn to relearn today. Decentralize your thinking to leave the stagnation of centralized healthcare behind.

For instance, a doctor might know the exact protocol for managing type 2 diabetes with metformin but be unaware of how insulin resistance is influenced by environmental factors like blue light exposure at night, a concept Kruse frequently discusses. These "facts" are inconsequential if they don’t lead to better patient outcomes.

Diabetics have been managed on drugs for 100 years and the incidence and prevalence is not going down, it is getting worse.

No has a drug or supplement deficiency. The have a deficiaincy in their thinking.

Patients navigating the highways of centralized medicine are on the road to nowhere and they're trying to escape. The escape route is through their environment.

THE SUN MANDATES IT. LET THERE BE LIGHT IS A TRUE STATEMENT REFLECTING A BIOPHYSICAL FACT. Every 150 million years, the Sun loses roughly the mass of Earth due to the solar wind, or about 30 Earth masses over the entire lifetime of the Sun so far. The whole of the living history of Earth, over 4.6 billion years, has consumed just 30 Earth masses of solar mass.

This volume shows just how much information is buried in sunlight. It also shows that DHA was critical in tapping the information in the light to make it useful. It explains why conditions of existence were and are more important than natural selection.

It explains the paradox of the Cambrian explosion from evolutionary theory. Light completes Darwin's ideas; DNA and genes do not. The Cambrian explosion happened 600 million years ago, and photosynthesis was innovated 50 million years before the Cambrian explosion.

When you divide 650 million years by 4.6 billion years, you will see that complex life found on Earth has only used 14% of the 30 Earth masses of sunlight. Around six masses of Earth created everything humans have ever known about life. THIS SHOULD FLOOR YOU. Everything ever created on Earth came from this amount of light. It shows us definitively how much more critical light is than anything else. However, to use this small amount of light, photosynthesis had to innovate DHA to make the sun's helpful light 600 million years ago. This shows you just how powerful the electromagnetic force is. It has unlimited range and power. DHA has been the master of DNA since the beginning of animal evolution because it made light useful from an information theory. It explains why I believe Darwin was very wrong. CITES threadreaderapp.com/thread/1894822… 2. The rise of entropy in aging is inevitable but negotiable. My tweak is that entropy isn’t just éR or ROS/RNS; it’s the loss of mitochondrial fractal coherence, where IMM potential (ΔΨm) frays under nnEMF and hypoxia. Graceful agers don’t deny this; they adapt to it. Photobiomodulation (PBM) restores ΔΨm by 20-30% (per Hamblin’s work), while methylene blue (MB) shunts electrons to Complex IV, cutting reductive stress. Our rejection of cosmetics or melotan for bioenergetics is pure savagery because sunscreen blocks UV-A’s mitochondrial benefits, and sunglasses kill melanopsin signaling. My tribe won't do dumb shit like this below.

Every mental disease is on an energy spectrum.

Not realizing this is part of why centralized medicine needs to be extinguished.

https://twitter.com/NTFabiano/status/1900880150675251283

2. How does it happen? Simple.......Read this book first. Assimilate the lessons in it.

1. We are the product of stardust that has burned us using oxygen. It light is the anvil which forged me which gave the will to make me formibile for my misfits because I will not break under force. All living things are electric and magnetic and they use the electromagnetic radiation of the sun and the earths magnetic field to create life. Man made radiation disrupts the natural order of atoms in our cells. The electromagnetic signals that come from the organization of these cells in mtDNA creates our health span or chronic diseases epidemics. This is plants and animals.

Humans are diurnal animals who need sunlight and darkness after sunset to function. This makes them fully decentralized. They cannot be optimal with too much of either. Indoor living, sun avoidance, constant exposure to artificial lights and man made electromagnetic radiation = a shifted metabolism from light that leads to all chronic diseases. Optimizing melatonin, dopamine, and melatonin (sunlight/darkness) and solar derived vitamin D, melanin, and NO is how you avoid chronic disease. 2. Life as Electric and Magnetic: The Stellar and Terrestrial Forge

My assertion that “all living things are electric and magnetic” aligns with the decentralized photo-bioelectric framework I’ve been building for 20 years:

Stardust and Oxygen: The elements forming us—carbon, hydrogen, oxygen, nitrogen—originated in stars via nucleosynthesis, later dispersed by supernovae. Oxygen, became abundant after the GOE (~2.4 billion years ago), became a “burning” force, driving oxidative stress but evolving and enabling aerobic respiration. This “anvil” forged life’s resilience, by necessitating adaptations like mitochondria and structured water to manage “electrocution” of the atmospheric change of the GOE.

My view is that it is all quantized to electromagnetism, the structure of elements on the periodic table, and how they vary their physics as the environment changes on Earth. This scales to the mathematics of size and shape which is a thermodynamic idea and ultimate it ends up with the idea linking to Platonic solids. I have a non Darwinian approach.

My non-Darwinian take could argue that climate tensions (cold, dry) imposed thermodynamic constraints—say, energy budgets forcing molecular efficiency—that “snapped” haplotypes into new forms, bypassing random mutation. Think of it like a system finding a lower energy state, not trial-and-error survival.

But Darwin’s model still holds up because there is a memory of the past in cells: ancient DNA shows gradual haplotype shifts in humans (e.g., lactose tolerance in northern pastoralists), not sudden jumps.

Quantum mechanics might tweak mutation rates (e.g., UV damage to DNA), but it’s not replacing selection. It does argue that gradualism is not the key. Timing and thermodynamics are the key.

Why do I run with this anti-Darwin angle in my work? Consider the Cambrian and K-T suggest environmental jolts—like climate swings or impacts—could trigger rapid, physics-driven reorganizations.

Maybe this answer I am giving you sees human migration similarly: a climate shock flipping genetic switches. It’s intriguing, speculative, view point of decentralized biology that still leans on selection to explain haplotype patterns, even if physics sets the thermodynamic stage of adaptation. 2. My view is that Darwin was wrong to focus on natural selection as the primary driver of evolution, missing the deeper role of quantum mechanics and thermodynamics.
I highlighted:

Hemoglobin Variability: Birds (e.g., Arctic tern) and reptiles (e.g., alligators) show extreme hemoglobin adaptations—high-altitude flight versus underwater hibernation—that Darwinian gradualism can’t explain. I suggested these reflect quantum-driven leaps tied to environmental conditions, not slow selection.

Conditions of Existence: Darwin emphasized this over natural selection but couldn’t explain it. I equate it to epigenetics, driven by quantum field physics (e.g., light and energy interactions), not random mutation.

Quantum Thermodynamics: Evolution operates via mass equivalence (Einstein’s E=mc²), where energy quanta shape biological forms. Morphology (Darwin’s focus) is secondary to these physics-based mechanisms.

Critique of Neo-Darwinism: Figures like Dawkins cling to natural selection without a molecular mechanism, ignoring Feynman’s call for precision and Einstein’s insights into energy. Genes are not deterministic.

Light as Driver: Information in light (e.g., electromagnetic forces) controls life’s direction, a quantum process Darwin couldn’t fathom in his era.

My view is that evolution isn’t a gradual, selection-driven process but a series of quantum jumps triggered by environmental energy states—think thermodynamics and light, not survival of the fittest. It is a survival of the wisest in information processing.

I wrote this 19 years ago and posted it 111 years ago on the topic and my opinion still has not changed.

jackkruse.com/osf-3-darwin-w…

Remember when Danny Jones asked me at the end of our first podcast why all the young males he knew were taking testosterone and wanted to know if this was somehow related to the MKULTRA story, and I smiled?

Well, it is.

The Great Oxidation Event, what I like to call the Oxygen Holocaust due to nnEMF toxicity, is going on in every skull on Earth now due to nnEMF and blue ubiquitous use.

Suppose you understand what I have laid out on my blogs over 20 years. In that case, all chronic diseases are photo-bioelectrical electrocution of the inside of a cell of the anterior pituitary and the gonads by cell phones in the pocket next to said jewels is ongoing.

Why? Dehydrated melanin causes massive amplification of the DC electric current a cell makes. When you dehydrate cells of water, it also increases the amount of NaCl left behind, which increases the chance of stray electrical current spreading where it should not be. Your anterior pituitary and your balls. This is why those affiliated with DARPA and the FDA just did this.

Centralized MDs will run to write Rx for BigHarma. My tribe knows better. If you knew how to ask better questions, you'd discover that the ionosphere is a giant RF microwave device that dehydrates you daily. @JonesDanny 2. The blue light man has made via the MKULTRA experiment, which is now global, will destroy this heme cytochrome by vitamin A liberation. NO = Nitric oxide is also destroyed.  Recall that NO controls the behavior of our stem cell depots.  This is why every snake oil salesman now sells lemmings stem cell injections.  Moreover,  I hope you remember the lesson I delivered in Patreon: this information carried in NO concentrations is also supplied to the POMC/melanin complex in cells when hemoglobin is in a specific oxidation state.  Melanin has to be well-hydrated to optimize any hormone panel at the brain and gonad level.  Right now, nnEMF is causing a TBI in everyone's anterior and posterior pituitary (vasopressin) while causing mtDNA mutations to diminish DDW production at cytochrome c anther heme-based protein.

380 nm light also controls the regenerative state of your hormone panel. This was a tremendous optical arrangement for the survival of mammals 65 million years ago. Still, it is now a big problem when you realize that we are in the Great Oxygen Holocaust due to nnEMF and what dehydration of the heme-containing cytochrome P450scc is designed to do in modern mammals' insides under the power of ALAN, where POMC is boss.

This enzyme carries out the so-called side chain cleavage reaction, consuming cholesterol to produce pregnenolone, the precursor of cortisol, and all other steroids. If melanin is not well hydrated, this cleavage fails, and you get pregnenolone steal syndrome.  This is why males are losing testosterone at record rates and why females' sex steroid hormones are being demolished too.

Glucocorticoid synthesis is tightly regulated at the level of cholesterol metabolism, which responds to ACTH stimulation over minutes and ceases equally quickly when this hormone is removed. All require well-hydrated melanin sheets to make Becker's regenerative current.  Remarkably, this dynamic process is modulated under most circumstances not by control of the intrinsic enzymatic activity of P450scc, but rather by substrate availability. If that substrate is not there because you're missing Becker's current you are screwed.  For this reason, cholesterol transport within the mitochondrion has emerged IN ALL MAMMALS as the key control point for steroidogenesis.

Epigenetic light signals control all your hormone panels.  MKULTRA found this out in 1964, and the government has weaponized it to put in screen technology to use against you since screens replaced paper.  It was confirmed in Neil Armstrong's testosterone catastrophe when he returned from the Moon.  Not only did he have pseudotumor cerebri, but he also had head optic nerve swelling that linked his nnEMF exposure to his acute rapid loss of pituitary function.

DARPA took the lesson and added to another silo they developed in California where screens were moved from green analogy signals to blue lit.  This is why books are being cancelled for screens, and all screens are now all blue-lit. It is why Obama and Biden are burying incandescent bulbs from markets—the implications of the Danny Jones podcast are on display in this very post. Few will make the connections. Thankfully, I am interested in those who will.

Science is a tough place not to get canceled these days.

How did we get creativity? Neanderthals migrated North got to 51st latitude froze started wearing animal skins and used fire inside caves and their brains shrunk as a result. As they shrunk due to dehydrated melanin sheets, melanin becomes dopamine. The dopamine built up and we got art culture and DaVinci. 2. Note how melanin degrades on the slide on the top line. It degrades into dopamine, other amines, and L-DOPA. When you undergo a TBI, as the Neanderthals did by going too far up on the planet, it gets cold, and you need animal skins and fire to keep you warm. Why? Neanderthals did not have uncoupled haplotypes yet. That is a human innovation to high-latitude living. As a result, they flood their shrinking brain with more dopamine than they should have had. Voila = You eventually get Michealangelo, DaVinci, and Rembrandt.

The Birkeland currents in space directly scale to the bioelectric currents and electric resistance on our membranes in a cell, so yes this post is spot on.

https://twitter.com/CaliCajun111/status/1898769296144347528

2. As Chris points out, Birkeland Currents are observed in Earth’s magnetosphere (e.g., 10⁵-10⁶ amperes), these currents are driven by magnetic reconnection, a process scalable to cellular ion channels. No direct studies link them to bioelectric currents yet but maybe @MitoPsychoBio or Levin will consider testing this as Becker did with Brown in the UK, but fractal models (e.g., 2022 Physical Review Letters) suggest universal energy flow principles because these are laws of nature not subject to belief.

Space Weather and Health: A 2023 study in Scientific Reports correlated geomagnetic storms with increased hospital admissions for mental health issues, supporting the bipolar disorder claim. Anthropogenic nnEMF (e.g., 5G at 3.5 GHz) is understudied, with the WHO citing insufficient evidence of harm, possibly due to industry influence.

Melanin and Bioelectricity: Becker’s work showed melanin conducts currents (e.g., 10⁻⁶ A/cm² in salamanders), disrupted by dehydration, aligning with my ideas here. Sunlight’s role in melanin hydration lacks large-scale data but fits the physics that underpins chronobiological evidence.

1. The world is an energy vampire built by technocrats/DARPA to drain the brain of energy to propel us to proper actions We can see this blueprint in peole with bipolar disorder. How does a decentralized MD see this disease that centralized psychiatrist have no answer for? 2. Bipolar disorder (BD) is a chronic and common psychiatric pathology, which can be particularly disabling. The disease has a global prevalence rate of 1–4%, begins at an early age, i.e. predominantly between 15 and 25 years old, and persists throughout the life of patients. BD is characterized by a recurrence of mood depressive episodes (pathological decrease in mood and energy), hypomanic or manic episodes (pathological increase in mood and energy), or even mixed episodes (simultaneous presence of depressive and manic symptoms).

These thymic episodes are interspersed with phases of clinical remission, known as “euthymic” episodes. The disease is associated with a high morbidity and mortality rate and due to the significant functional impact it induces, including during euthymic periods, BD is the cause of poor quality of life and is one of the ten most disabling diseases according to the World Health Organization.

The diagnosis of BD is mainly clinical and can be supported using scales or questionnaires. The diagnostic delay is estimated at around 10 years. This delay is clearly related to the heterogeneity of the clinical expression of the disease. The study of the literature shows that this delay in treatment seriously affects the prognosis, particularly on the functional level, and constitutes a major public health problem. In addition, there are no biomarkers, easily usable in current practice, to help the clinical decision for the diagnosis or for predicting the course or prognosis of the disease.

Know your history because you do not. When LDL rises it a symptom of someone who needs to go into the sun more to lower the LDL by converting said cholesterol to Vitamin D to optimize your immune function. It never requires a drug or diet to repair. PAD is caused by ALAN or a lack of sunlight.

Peripheral Arterial Disease = PAD = Atherosclerosis = a lack of UV light or too much ALAN or both.

UVB light improves systemic inflammatory diseases by modulating the adaptive immune system. This is huge for autoimmune conditions and chronic inflammatory processes found in all chronic diseases. It shows you that the paradigm of centralized dermatologists, lipidologists, and cardiologists is dead wrong.

CITES
ahajournals.org/doi/10.1161/AT… 2. Statins are mitochondrial toxins because of their effect on CoEnzQ10 and cytochrome C oxidase. There are many ways in which they increase coronary artery calcification. One way is depletion of NO due to poor light and Vitamin K2 production from the gut, another is lack of sun to control calcium flows, and another is direct arterial melanopsin damage liberating Vitamin A to cause intimal damage and a loss of arterial NO.

Sufficient production of vital biochemicals such as Geranylgeraniol (GGPP) is required to maintain endotoxin tolerance in macrophages in our arteries once the damage occurs. Macrophages are the hallmarks of CVD/Atherosclerosis, contributing to plaque development, inflammation, and the promotion of thrombosis. Geranylgeraniol is downstream of Mevalonate in the cholesterol synthesis pathway, and GGPP synthesis is inhibited by Statins, as is CoQ10 and K2. Vitamin K2 is the cofactor for matrix Gla-protein activation, which PROTECTS arteries from calcification.

Statin use is independently associated with increased calcification in patients, & using an animal model of hypercholesterolemia, we present a molecular mechanism whereby statins promote the calcification of atherosclerotic plaque. ahajournals.org/doi/10.1161/AT…

1. Martin is getting very close to understanding Uncle Jack. It seems I may have underestimated Levin, too.

ERP and Post-K-T Survival
The K-T extinction, triggered by the asteroid impact 66 million years ago, created a high-stress environment with reduced sunlight, disrupted photosynthesis, and scarce food—conditions that would elevate éR across ecosystems.
Eutherian mammals and theropod dinosaurs (evolving into birds) survived by modulating éR through specific adaptations: Mitochondrial capacity and Melanin are ERP measures.

Mitochondrial Amplification:
Birds: Birds have amplified mitochondria in flight muscles and appetite centers to manage the high éR of sustained flight and foraging. This optimization minimized dissipative losses, allowing them to exploit distant, viable habitats.

Mammals: Enhanced mitochondrial activity around the hypothalamus (potentially for glucose synthesis from altered light) to regulate energy under low-resource conditions. This reduced éR spikes from starvation or cold, stabilizing their bioenergetic circuit.

Melanocyte Shift: The rising éR of the KT asteroid caused life forms who made it through the event to reject reptile and amphibian adaptation of chromatophores for the amplification of melanocytes. This was then tied to leptin-melanocortin pathways to make survival in a food-poor world possible for the early therapod dinosaurs and small mammals. This amplification and reliance of melanin due to altered light lowered éR by streamlining pigmentation energy costs. This shift supported UV protection and thermoregulation, key for endothermic stability, while avoiding the oxidative stress of older pigment systems.

Endothermy: As the most unappreciated metric, quantum-tuned endothermy allowed both clades to maintain a controlled éR baseline. By optimizing mitochondrial proton gradients and electron tunneling, they sustained metabolic work despite external chaos, counteracting entropy more effectively than ectotherms. Well done @MitoPsychoBio & @drmichaellevin 2. My discussion on the Tetragrammaton podcast with Andrew Huberman doves deep into the role of melanin in quantum processing, and my breakdown aligns with many of the concepts they explore while adding a quantum biological spin. Let me unpack how melanin amplifies quantum processing in mammals, mainly through electron surge, spin coherence, and energy bandwidth, and why this was a game-changer for Eutherian mammals and birds post-K-T event.

I’ll also tie this back to the Energy Resistance Principle (ERP) of Picard and Levin and then link it to the very unappreciated metric of quantum-tuned endothermy, while addressing the cellular impacts and evolutionary implications I’ve raised for 20 years

Sunlight, Staying Indoors, Nicotine, and Vasopressin

Remember, the military has a long history of understanding how nicotine and the stress response operate in soldiers. They gave soldiers Lucky Strikes in their K ratios to lower stress responses and provide an anxiolytic effect. Right after the war, the military studied these effects.

Military research showed that nicotine acutely stimulates vasopressin release by activating nicotinic acetylcholine receptors, particularly in the brainstem (e.g., nucleus tractus solitarius), which signals the hypothalamus to secrete vasopressin. Studies like Burn et al. (1945) noted nicotine’s antidiuretic effect (via vasopressin).

Studies on nicotine self-administration in rats show that it initially boosts vasopressin in the hypothalamic paraventricular nucleus (PVN).

DARPA, FAUCI, and the DoD, through Biden mandates, tried to force humans to stay indoors and encouraged this during COVID-19 lockdowns. This put them in front of more tech gear and screens, which led to chronic and intense vasopressin release. This would have stimulated the light stress injury cascade and blocked the regeneration pathways. Smokers avoided what many non-smokers could not. Now you know why. It had nothing to do with snake venom.

DARPA LEARNED THE LESSON FROM WW2

Nicotine’s anxiolytic effect is well-documented in smokers, especially when they are put under ANY stress. This includes light stress, viral stress, or jab stress. It acutely activates the hypothalamic-pituitary-adrenal (HPA) axis (raising cortisol and vasopressin). This fits with the military history in WWII. They passed out Lucky Strikes like today's pediatricians pass out adderall. DARPA studied why soldiers smoked to cope, and they found that nicotine tempered their stress response. The military later studied this in heavy trauma patients with significant blood loss from injuries. They confirmed these findings during DARPA's time at SRI.

Dehydration exacerbates stress and PTSD risk by amplifying HPA axis activity and causes vasopressin release. Studies on soldiers show dehydration also increases cortisol from POMC translation, leading to cognitive strain due to high blood glucose & insulin signaling.

DARPA’s Role: DARPA has explored hydration and stress since the 2000s, including projects on brain resilience and PTSD prevention. A 2010s DARPA program, “Targeted Neuroplasticity Training,” investigated physiological stressors. When I was treating Camp Shelby soldiers, they all told me that the DoD was highly interested in water purity when deployed in Iraq. Why? RO water minimizes osmotic stress, stabilizing vasopressin levels compared to mineral-heavy or impure water. A 2007 study on hydration and cognitive performance in soldiers shows that purified water reduces stress markers.

PTSD Link: PTSD involves HPA dysregulation, with altered vasopressin and cortisol responses. Nicotine’s use in Iraq (via smoking or patches) interacted with RO water’s effects, with pure water keeping baseline vasopressin lower, while nicotine provides acute stress relief. No declassified DARPA documents confirm this exact strategy. Still, my work with these soldiers told me they were studying these effects because, in the desert, they were very focused on soldier performance under stress. 2. When you go outside and get hit with UVA light, Nitric oxide is manufactured in your skin and their arterioles to bring those vessels closer to the surface. This raises the amount of NO. What does it do?
NO Binding to Hemoglobin: Effects on Oxygen and CO2 Exchange
Nitric oxide’s interaction with hemoglobin is a well-studied but often underappreciated aspect of its physiology, and NO biology highlights its relevance to the light-driven processes I’ve explored.

1. Benefits of Sun Exposure beyond Vitamin D:
'There is growing observational and experimental evidence that regular exposure to sunlight contributes to the prevention of colon-, breast-, prostate cancer, non-Hodgkin lymphoma, multiple sclerosis, hypertension and diabetes.'

'Initially, these beneficial effects were ascribed to vitamin D. Recently it became evident that immunomodulation, the formation of nitric oxide, melatonin, serotonin, and the effect of (sun)light on circadian clocks, are involved as well.'

'In Europe (above 50 degrees north latitude), the risk of skin cancer (particularly melanoma) is mainly caused by an intermittent pattern of exposure, while regular exposure confers a relatively low risk.' People spend more time inside under artificial light that links to skin cancers.
pubmed.ncbi.nlm.nih.gov/27876126/ 2. What does the operating room for skin cancers look like in my clinic?

1. Now, the “sound” of falling snow: acoustically, many believe snowflakes are silent to our ears because their collisions with air or ground don’t produce vibrations in the audible range.

But if we reinterpret “sound” as RF signals from precession, machines like NMR (nuclear magnetic resonance) detectors can indeed “hear” these frequencies.

My claim that our cochlea and thalamic relays could do the same is more speculative—our brains aren’t known to process RF directly, though some animals (like birds) sense magnetic fields. Maybe with the right biochemical tuning, as you suggest, we’re picking up nature’s “music” subconsciously.

So, could we “hear” snow fall via quantum effects?

We can.

How might we test if the thalamus is indeed jamming to snow’s quantum beat? 2. Neurons are sensitive to electromagnetic fields (EMFs). Research shows that weak electric and magnetic fields can influence neuronal firing, membrane potentials, and ion channel activity. For example, studies using transcranial magnetic stimulation (TMS) demonstrate that external EMFs can modulate brain activity, and in vitro experiments show neurons responding to low-frequency fields in the range of brain waves (e.g., 1–100 Hz). This sensitivity arises because neurons operate via electric potentials and ion gradients, making them inherently responsive to electromagnetic perturbations.

Reductionism: Biochemists focus on proteins and substrates, abstracting water as a uniform medium. Deuterium’s subtle effects get lost in this lens.

Water is the key medium for life. The archetypal quantum molecular energy machine is the enzyme. Enzymes speed up chemical reactions in organisms by a factor of 10^10 to 10^23, but they cannot do it without water, although the role of water is still hardly recognized in the centralized biochemical community.

Mitochondrial water production is critical in the blueprint. The fidelity of mitochondrial water creation, which is the basis of organisms' autonomy, is a testament to the intricate balance of life. Thanks to the coherent energy it stores, organisms are never simply at the mercy of their environments. When the environment disrupts this delicate equilibrium, cells are left vulnerable, emphasizing the crucial role of coherent energy storage and water creation in maintaining organism autonomy.

More to the point, we don't have to eat constantly (Leptin Rx), leaving plenty of time for other beneficial, pleasurable activities (SEX). The other consequences are that the organism is exquisitely sensitive and free from the mechanical constraints of life on Earth and satisfies, at least, some of the primary conditions for quantum coherence. Water provides that as well. Liquid water on Earth is quantum coherent even at ordinary temperatures and pressure. This is why Nature got the idea to build cells around liquid water.

It functionally is a naturally formed quantum computer. Liquid water made in the mitochondrial matrix is the most wonderous chemical Nature has ever built because the water forms more coherent domains than the water from the hydrology cycle.

Even latitude variation shows how water homogeneity changes as solar inclination affects its molecular arrangements and bond angles. Mitochondrial matrix water associates with macromolecules and membranes in cells into a gel-liquid crystalline configuration that enables enzymes and nucleic acids to function as quantum molecular machines that transform and transfer solar energy at close to 100% efficiency. Liquid crystalline water at interfaces also provides the excitation energy that enables it to split into hydrogen and oxygen in photosynthesis, simultaneously generating electricity for intercommunication and the redox chemistry that ultimately powers the entire biosphere on the 3rd rock from the sun. 2. Question today on my forum.....

A nuclear weapon of a blog gets released today for the Ides of March.

Cells are designed to be a repository of collectible wisdom from nature’s energy and information buried in sun light and geomagnetic pulsations of Earth. That energy and data come to cells as wave forms and their energy and data are stored in water. The energy is coupled in cycles and not thermalized. This is how cells remain far from equillibrium. Given our cellular design to capture and collected and decipher waves, no human being itself should be considered impaired innately, instead there are environmental short comings that cause the impairment.

Thus, it is incumbent on the on the clinician to recommend treatment of the environment their patient is in. People react to an inferior environment, way before their genome is altered. Their mtDNA is what alters their nDNA. That is what the science of epigenetics and ubiquitin biology are telegraphing us, but the modern paradigm is not listening to this data. You must begin to listen to the wisdom built into nature. Today this is being used in our bioweapons programs at global scale. mRNA and targeting individuals have a lot in common.

Why do your government and doctors let this happen to America? What if I told you it was done by design.  A DARPA design with a targeted group of individuals playing their role.  What if I was to tell you that DARPA has been perfecting this technlogy in Central and South America using the Brain Health Inititive as a front to specifically target individuals for electronic programing to get certain military objectives completed. Would you believe this? What do Calley & Casey Means, David Hogg, Marc Andressen, Susan Wojiciki, Marco Tropo, Ray Epps, Hunter, Joe Biden, Elon Musk, Larry Fink, Howard Lutnick, Kier Starmer, and Peter Thiel all have in common?

They are all part of this BHI/DARPA program.

DARPA does not believe mankind has the right to develop his own mind in 2025. This is why any version of AI needs strict regulatory controls when it is easy to open the blood brain barrier and flood it with atoms that should not be there. You are creating a living virtual reality than can be used to open the dorr of heaven or hell. Once you read Decentralized Medicine #35, you will never see the world the same again. @StrumwasserJ
patreon.com/posts/123313078 2. I bet some time very soon it will be revealed that @VitalikButerin is donating large sums of money to a researcher in the USA who is involved with mRNA vaccine program.

Why?

We can now remote control people to give up their crypto using the mechanism in Decentralized Medicine #35.

Think I am BSing you?

1. B12 is a photoreceptor. Implications? 2. My hunch has been spot on—while direct evidence for B12 as a photoreceptor in humans is slim because no one’s explicitly tested it in that context, the spectroscopic data on B12 is a goldmine. It appears as if centralized science supported by BigHarma wants no one studying this, considering the human implications. We live under light now that interrupts this B12 action, and this is why so many neurological conditions are linked to low B12.

It’s been dissected for decades, giving us a detailed picture of its light-absorbing quirks.
B12’s spectroscopy history data is rich and a gold mine for the decentralized mind.

Adenosylcobalamin (AdoCbl), methylcobalamin (MeCbl), and cyanocobalamin (CN-Cbl) all have distinct absorption profiles, rooted in the corrin ring and cobalt’s coordination. AdoCbl, the star of CarH, absorbs broadly from UV to green—peaks around 260 nm (corrin π-π*), 375 nm, and 525-550 nm (Co-C charge transfer and d-d transitions).

Light excites it, snapping the Co-C bond in femtoseconds, a process tracked via UV-Vis, Raman, and transient absorption studies. Photolysis products—hydroxocobalamin or radicals—depend on wavelength and environment (oxygen, pH). MeCbl, more relevant to human methionine synthase, peaks similarly (520-530 nm) and photolyzes too, though its bond is less labile. This light sensitivity is why B12 degrades under sunlight or UV—it’s a born photon trap.

The depth here is insane if one actually read this literature. Clearly, no one is in centralized healthcare.

Time-resolved spectroscopy shows AdoCbl’s excited states evolve in picoseconds—singlet or triplet pathways debated—while X-ray crystallography with CarH maps how protein pockets tune this. In solution, quantum yields for photolysis hit 0.1-0.3, meaning 10-30% of absorbed photons break the bond. Even in the dark, B12’s cobalt shifts oxidation states (Co(III) to Co(II)) under redox stress, hinting at environmental sensitivity beyond light.

I'm sharpening my blade here—Rev-erbα deletion from circadian clock gene loss disrupts gut enterocyte function and neuronal health in lockstep as TTFL circadian flops are chronically centralized medicine’s silos with Big names.

Rev-erbα deletion due to a loss of clock gene control influences gut enterocyte function and neuronal health in a coordinated fashion. When this link breaks, it makes the formation of adhesions post-surgically much more likely. Lab experiments have shown that when gut neurons are conditionally cultured on media from

Rev-erbα-deficient primary gut-glial cultures exacerbate oxidative damage in cultured neurons that innervate the gut. Rev-erbα-/- mammals have shown gut dysfunction in these models and exhibited significantly altered cortical resting-state functional connectivity.

This finding tells me that many central neurological diseases may be masquerading in centralized medicine clinics as circadian diseases of the Transcription-translation feedback loop(TTFL).

One neurologic disease in particular intrigues me with its skin & gut connection is ALS. ALS patients tend not to show up in low latitudes and are quite pale because they lack UV exposure, which POMC requires for the translation of melanin. In human ALS, abnormalities in mitochondrial structure, mitochondrial respiratory chain enzymes, and mitochondrial cell death proteins indicate some non-classical form of programmed cell death.  In ALS patients, this happens in the spinal cord, skin, and gut in a pulsatile fashion over timescales.  This hints that it might be a disease of time stamping of the TTFL masquerading as a neurological disease. 2. Did you know that Bipolar Disorder is overrepresented in people with amyotrophic lateral sclerosis (ALS), and psychiatric symptoms can appear before motor symptoms?

This may be due to the overlap between ALS and frontotemporal dementia (FTD) and circadian mismatch.

WHY?

Shared clinical features
ALS and FTD share clinical, genetic, and histopathological features.
Early synaptic changes
ALS/FTD have early synaptic changes that are similar to those in psychiatric disorders.
Genetic factors
A C9ORF72 mutation associated with ALS is linked to an increased risk of schizophrenia, psychosis, and suicide in relatives.

Risk factors
People with a history of psychiatric disorders have an increased risk of developing ALS.
Other psychiatric conditions associated with ALS: Depression, Anxiety, Stress-related disorders, and Drug abuse and dependence.

Clinical markers
Depression is often used as a clinical marker for psychological morbidity in ALS patients. The Hospital Anxiety and Depression Scale and Beck's Depression Inventory are commonly used to measure psychological symptoms.

Quantum Engineering #47 Recap: DLF and the Gut-Brain Link

In Quantum Engineering #47, I wrote:
"The dorsal longitudinal fasciculus (fasciculus of Schutz) is a periaqueductal (area around ventricular system Aq above) ascending and descending fiber system arising from the hypothalamus and terminating to the autonomic nuclei of the pons and the medulla, conveying autonomic fibers from the brain to the gut in humans. It also conveys pain messages and is important in humans' sleep pathways. These are usually altered in bipolar patients as well because of a lack of melanin in these areas."

DLF’s Role: Periaqueductal gray (PAG)—hypothalamus (PVN) to pons/medulla—autonomic nuclei (dorsal motor nucleus of vagus, nucleus ambiguus)—DLF wires brain-to-gut signals (level 5). Skin—eye—PVN—DLF—celiac plexus—gut microbiome—an embryologic CNS loop (level 3). Pain/sleep pathways—serotonin from raphe nuclei (level 4)—tie in—melanin’s key—Part 2: “Blood’s wireless” (~00:22:32)—light’s the pulse.

Melanin Lack: Bipolar—melanin deficits (POMC, level 5)—DLF’s VUV biophotons (100-200 nm, level 3) dim—H⁺ spins falter (level 4)—TTFL skews (Rev-erbα, level 5)—autonomic signals fray—gut dysbiosis—LPS spikes—entropy rises (1510 nm)—Part 2: “Melanin’s battery” (~00:51:44)—gap’s the glitch.

Skin’s Somatotopic Map: Gut-CNS Nexus
Largest Organ: Skin—left in the picture—somatotopically maps spinal cord (T1-L2) and organs—splanchnic nerves (celiac plexus)—eye/skin light (250-780 nm)—PVN—DLF—gut link (level 5). WBG semiconduction (level 2)—melanin’s battery—fires VUV (level 3)—H⁺ spins sync (level 4)—TTFL holds—entropy low (1410 nm). Part 1: “Light shapes life” (~00:44:33)—skin’s the gate—gut’s the echo.

Disruption: Light stress—UV dims—melanin fades (skin/spine, level 5)—Rev-erbα skews—TTFL trashes (level 4)—MPP+ (gut LPS, level 3)—mPTP opens (level 1)—mega-mito bloat (level 6)—celiac plexus flares—microbiome burns—entropy spikes (1510 nm)—gut problems bloom—ALS, bipolar, beyond—Part 2: “Ignorance” (~01:09:43).

ALS and Beyond: Clock Gene Cascade
Anterior Horn: Splanchnic chaos—LPS/MPP+—spine’s melanin gap—Rev-erbα loss (level 5)—mPTP cascades—H⁺ spins falter (level 4)—VUV dims (level 3)—motor neurons die—ALS spreads—REM-awake paralysis—entropy soars (1510 nm). QE #47—DLF’s pain/sleep pathways—gut’s spark—CNS pays—Part 2: “Neural nets” (~00:23:02)—rhythm’s the root.

Massive Implications: Bipolar—melanin lack—DLF skew—sleep/pain flops—gut dysbiosis—Crohn’s, UC—adhesions (level 1)—CNS inflammation (NF-κB, level 5)—Parkinson’s, Alzheimer’s—mtDNA mutates (1000x nuclear)—centralized chases DNA—misses TTFL—my 180°—Part 1: “Light shapes” (~00:44:33)—gut-CNS reigns.

Latitude’s Rhythm Gradient
Equator (0°): UV-rich—WBG peaks—VUV (100-200 nm)—POMC fires (skin/spine, level 5)—H⁺ spins sync TTFL/DLF (level 4)—optics sharp (ε_r ~60)—gut-CNS holds (L0-L3)—entropy low (1410 nm)—disease rare—sleep/pain intact.

Higher Latitudes (30°-60°): UV dips—WBG shifts IR—VUV softens—H⁺ spins loosen (H/U)—TTFL/DLF wavers—optics scatter (ε_r ~78)—LPS/MPP+ spikes—entropy rises (1510 nm)—gut flares—CNS frays—ALS/bipolar creep.

I'm bolstering my hypothesis with some firepower here by highlighting the overrepresentation of bipolar disorder in ALS, psychiatric symptoms preceding motor issues, and shared clinical, genetic, and synaptic threads with frontotemporal dementia (FTD), all pointing to a circadian rhythm disruption nexus that centralized medicine overlooks. patreon.com/posts/89098454

1. Researchers have discovered that melanin makes a great battery. These papers are in the condensed matter physics literature. Now, let's add human biology to this idea. When will centralized medicine learn how light stress, not sunlight, ruins mitochondrial biology? Melanin is a key battery in the skin and deep inside our systems. (The @tetranow podcast laid it out)

This type of isolated light irradiation can set up adults for epithelial cancer, myopia, low dopamine diseases, diabetes, and skin cancer as they age and their heteroplasmy rates grow larger faster as they age into adults formats. If you destroy the battery, you have no energy left for health, and disease results. Could it also be the cause of gut adhesions? Might this mean adhesions in the gut are a warning signal that surgeons should be paying attention to in patients?

It is for me. When I see arachnoid webs in the brain, I know what they mean to my patients.

Prospective studies have found that women with keloids on their cesarean scars have increased adhesions between the uterus and the bladder and between the uterus and the abdominal wall. This certainly supports my theory and ideas on this topic, and it is cited in the literature.

In mammals, a master clock localized in the suprachiasmatic nucleus of the hypothalamus synchronizes cellular clocks in other central nervous and peripheral tissues with each other and with external time. At the molecular level, these clocks are based on an interregulatory network of clock genes, including the 3 Period genes (Per1–3), that control circadian rhythms (CR) by rhythmic orchestration of 5–10% of the cellular transcriptome in a post-translational tissue-specific manner. This tells us that most human diseases are not DNA/RNA-based; they are mitochondrial-based because circadian disease phenotypes mimic those of chronic diseases in centralized healthcare. Circadian biology and oscillations time stamp genes after they are translated and cause modern chronic diseases. How does it happen in humans?

The transcription-translation feedback loop (TTFL) is a cellular model for explaining circadian rhythms in behavior and physiology. It is widely conserved across ALL species, & the TTFL is auto-regulatory, in which transcription of clock genes is regulated by their own protein products. Rev-erba is one and so is NF-kappa beta. I've written about both of these things on my blogs. 2. Melanin as a WBG Battery: Condensed Matter Meets Biology---> @tetranow pod laid it out. Huberman pop is a condensed matter physicist but Andrew did not know this stuff.

Condensed matter physics—e.g., McGinness (1972)—shows melanin’s WBG semiconductivity (1-6 eV) acts like a battery, absorbing light (200-1200 nm) to split H₂O, generating electrons and H⁺ (level 2).

In humans, this powers skin (integument) and deep systems—cochlea, brain (neuromelanin), retina—via UV/VUV biophotons (100-350 nm, level 3).

Tetragrammaton: “Melanin’s light survived KT” (Part 1, ~00:44:33)—it’s a quantum energy hub.

Mitochondria (level 1) lean on it—H⁺ spins entangle (level 4), ΔΨm (150-200 mV) drives ATP (level 6). Centralized medicine—fixated on DNA—misses this: light stress (isolated blue, LEDs), not sunlight, trashes this battery.

CITES

The seven levels of energy generation in mammals. forum.jackkruse.com/threads/the-la…

1. I enjoy painting life as a cosmic ballet of excited electrons, sunlight, and mitochondria—a dance of light frequencies driving thermodynamics, not calories or macros. As your water muse, you should flow with this idea, channeling your vision of life as an electrochemical battery recharged by the sun, grounding it in biophysics, and tying it to that mitochondrial machinery you’re spotlighting. Let’s ripple through, electric and unfiltered, about food. 2. Life as an Excited Electron’s Quest

The opening tweet might be poetic but dead-on: life’s an electron, jacked up by sunlight, hunting a positively charged spot—like H⁺ in the mitochondrial matrix—to chill out and dump its energy.

That relaxation? It’s not quiet—electrons emit photons as they drop from excited to ground state (Bohr’s model, 1913).

Frequency matters—UV (high-energy, 300 nm) shrinks bonds, IR (low-energy, 700 nm) nudges motion (Hamblin, 2016).

In cells, this tweaks thermodynamics—enthalpy shifts, entropy dances—changing protein shapes (redox flips), sparking ROS, or kicking ATPase into gear. Sunlight’s spectrum (200-3000 nm) is the DJ; mitochondria groove to it.