The fascinating session on ‘Salt, water, vinegar, soda’🧂continues with @VelezNephHepato taking off with acid-base metabolism in liver disease. Such a treat! #ApexPathshala
Increased permeability of blood brain barrier in liver disease ➡️ respiratory alkalosis #ApexPathshala
‘In metabolic acidosis, lactate is a source of HCO3, but not in cirrhosis.’ Brilliant.
(Take a look at H+ ions combining with lactate, raising levels of free HCO3 ➡️ only if excess H+ ions exist,i.e. in metabolic acidosis.) #ApexPathshala
• • •
Missing some Tweet in this thread? You can try to
force a refresh
Dr.Theodor Fahr,the first modern pathologist & Dr.Franz Volhard,an internist from Mannheim🇩🇪,undo many prevailing misconceptions through formative work on Bright’s disease.
Their book👇🏻‘Die Bright’sche Nierenkrankenheit’ becomes a classic in the annals of glomerulology.2/n
1960s
Dr. Rene Habib,a pioneering pediatric nephrologist,studies a large cohort of children with MPGN &provides first descriptions of the disease.
Clinical & histopathological features of what formally gets named as MPGN l at the CIBA symposium convened at London in 1961. 3/n
It’s my first ever ‘Joel Topf lecture’ in person, and I’ve fallen in love with the slides. Pretty much the case with everyone else hearing him here today.
The slides flow like mental maps.🧠 Incredibly communicative! #ApexPathshala