Kevin McKernan Profile picture
Jun 16 4 tweets 2 min read Twitter logo Read on Twitter
There is a difference in saying SV40 promoters are not carcinogenic because they are missing the T-antigen …
And saying
We don’t know what will happen regarding genome integration.. or what will happen to the substantial part of the population already infected with SV40 virus. Image
A non trivial amount of the population already has SV40 virus capable of making the T antigen.

Injecting SV40 promoters and the SV40 origin into these patients may have unintended consequences. Image
Saying something doesn’t cause cancer and saying we don’t know are very different statements the fact checkers don’t like to face.

I go back to Keith Pedens work at the FDA looking at genome integration risks and oncogenesis.

While there isn’t direct evidence yet… Image
Saying never seems to ignore the reason we have these dsDNA limits in the first place.

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More from @Kevin_McKernan

Jun 15
My presentation at the FDA VRBPAC meeting today.
49 minutes in.
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Read 17 tweets
Jun 14
I like JJ Couey.

Since he doesn’t have much of a platform on Twitter and he feels l slighted him ‘dunking’ on his IC hypothesis,

It’s only fair I air his grievances to my whole audience. 4:20 mins in.
Nice 420!

analytics.twitter.com/mob_idsync_cli…
I have had emails with JJ going back to December alerting him to what I saw as some of the holes in his Infectious clone hypothesis.

It’s not fair to say I sprung a dunk on this. I would get asked repeatedly to address it and finally got tired of piecemeal explaining the issues.
So I wrote everything into one thread that probably felt like a blind sided attack since he’s not on Twitter. But most of this I had already aired to him offline.

I also took his feedback on a Substack I wrote on the topic and edited things.
Read 6 tweets
Jun 13
My experience with PubPeer has been very poor.
Wont let me register as my domain name at Medicinal genomics is not 'recognized'.

So if anyone else is registered and wants to point out this fake trace in a Drosten paper, please do.
There is no way... Image
The primers depicted in that extended data fig 1 generated those sanger traces as sanger doesnt sequence your primers. If a different set of primers were used to 'validate' the qPCR assay,
1)what were they?
2)using different primers to validate the fidelity of your PCR is fake
You are no longer measuring the fidelity of you PCR primers if you use a different one for sequencing.
The reverse primer can be read with Sanger if its close enough to the Forward primer (under 600bp). Must be on the 3' of the sanger trace for this to happen.
Read 5 tweets
Jun 10
Oncologist’s employer takes Pfizer donations.
Claims it’s against his institutions policy to sequence his fresh vaccines.
Demands I send them our expired vials that he spent days chastising the veracity of.

Never declares this conflict.

Our primers are public.
Conflicted parties don’t advance the field.

David has exposed himself as having zero impartiality on the topic.

He has access to fresh vials but won’t touch those.
He wants our vials which he claimed were insufficient for publication and an embarrassment to work with.
He has all the tools he needs to replicate this and address the problems he’s gone on public record with.

But he’s not doing this.

osf.io/b9t7m/
Read 8 tweets
Jun 7
Having been involved in the development of many novel sequencers, this is the worst paper on the topic I’ve ever seen.

It should concern you that Pfizer feels the need to invent a new sequencing method to understand their product after a billion jabs.

nature.com/articles/s4159…
Why the harsh criticisms?
Because they present no comparison to Illumina or ABI/Sanger sequencing.

It uses Mass Spec.
Mass information doesn’t sequence. The Mass of AAAG is the same as GAAA, AGAA, AAGA.

To overcome this they try to use LC.
Many separation tools also rely on Mass to charge to separate.

The technique uses RNAse T1 which cuts at every G.

So most fragments are 4-5bases long and occur randomly every 256 -1024 bases.

Sequencing a 4,284 bp sequence, this word size will occur 4-16 times by chance.
Read 12 tweets

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