Colin Keeley Profile picture
Jun 24, 2023 16 tweets 4 min read Read on X
Peter Attia is the #1 longevity doctor.

He charges $150,000 a year to be his patient.

His 13-steps for a long healthy life:
1. Our Goal

Lifespan is the number of years you live.

Healthspan is how long you’re healthy enough to do the things that matter to you.

Longevity means maximizing healthspan and lifespan.

Our goal is to live longer and live better.

It all starts with prevention...
2. Avoid Icebergs

Medicine 2.0 (medicine today) deals with problems after they present themselves.

Medicine 3.0 focuses on prevention over cures.

We are trying to avoid icebergs in the distance.

It is better and easier to avoid the first heart attack than treat it after.
3. The 4 Horsemen

There are four major killer diseases:

1. Cardiovascular disease
2. Cancer
3. Neurodegenerative disease
4. Type 2 diabetes and metabolic dysfunction

Metabolic health is the common thread.

Exercise is our best prevention.
4. Exercise

Exercise is "by far the most potent longevity drug”.

Weekly:
- Weight training 3 days
- Zone 2 training 3 hours
- VO2 max training 1 day

Get as fit as possible to prepare for natural decline with age.

Zone 2 training to stimulate mitochondrial function.
5. Marginal Decade

You want to intentionally train for the activities you care most about continuing into your later years.

Build up the strength and stamina while young to combat the predictable decline as you age.

Want to ski at 80? You better be in top 1% condition at 50.
6. Diet

Avoid fads. Attia recommends Keto (hard) or Mediterranean diet (easier). More monounsaturated fats & less carbs.

Avoid Standard American Diet:
- Highly refined carbohydrates
- Processed oils
- Added sugar

Eat more:
- Real food
- Avocados
- Olive oil
- Protein
- Nuts
7. Diet Questions

Are you undernourished or overnourished?

Are you undermuscled or adequately muscled?

Are you metabolically healthy or not?

Most have poor metabolic health, are over nourished, and are undermuscled.

You want to reduce energy intake while adding lean mass.
9. Heart Disease

Everyone 18+ has some degree of heart disease. Accumulating every day.

Get your ApoB and Lp(a) tested. Those matter more than cholesterol.

Goal: ApoB 20-30 (baby level)

Impossible to get there w/ diet & exercise alone. 80% of his patients take statins.
10. Cancer

Cancer is closely linked to metabolic dysfunction. Get healthy to avoid it.

This chronic inflammation creates an environment that induces cells to become cancerous.

Otherwise aggressive early screening is our best defense. Late detection is a death sentence.
11. Neurodegenerative Disease

Most difficult of the horsemen. Medicine 2.0 can't do anything for us.

What's good for the heart is good for the brain. Exercise & sleep are our best weapons.

Exercise maintains glucose homeostasis and healthy vasculature.

Sleep heals the brain.
12. Metabolic Dysfunction

Basically an issue in your body's fuel processing. On a spectrum.

Heart disease, cancer, and dementia are all built on metabolic disease. Each one is amplified by metabolic dysregulation.

Exercise, diet, and sleep are our weapons here.
13. Emotional Health

Emotional health issues are one of the biggest roadblocks to longevity in his patients.

if you are not happy, why would you want to live a long time?

Take care of your emotional well-being just like you would heart disease.

It's ok to admit you need help.
TLDR on Longevity:

Prevention is our best medicine.

- Exercise often
- Sleep well
- Eat clean

Follow me @ColinKeeley for more breakdowns.

Like/Retweet the first tweet below to share with your audience:
Source:

This is all from Attia's 500-page book on longevity.

It should be under 200 pages and be the best-selling book of the year.

The content is priceless.

amzn.to/3XkjvWn
Want to get more breakdowns?

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More from @ColinKeeley

Nov 5, 2023
Hiring in the Philippines is dead.

LATAM hiring is the future.

The 6 biggest reasons:
1. Timezone

The biggest difference.

LATAM is just south of the US.

Argentina & Brazil are one hour apart from New York.

Filipinos say they are ok staying up all night working our time zone, but it takes a toll. They sacrifice sleep, and their work and life quality suffer.
2. Climate

The Philippines has extreme weather. Severe rains with floods knock out the internet and prevent them from working.

LATAM has a temperate climate and fast internet.

This also lets them make some great wine.
Read 8 tweets
Jul 16, 2023
Andrew Huberman is the #1 health scientist.

I’ve listened to 100+ hours of his podcast and interviews.

His 7-steps for a long healthy life: Image
1. Morning Sun

Get sunlight in your eyes first thing in the morning every day.

- No sunglasses
- 20-30 minutes is ideal
- Glasses / contacts fine
- Windows filter too much
- Artificial light if up before sunrise

Light wakes up your body & sets a timer for great sleep later.
2. Delay Coffee

Delay caffeine consumption for 90-120 minutes after waking.

If you drink it too early, it screws up your body's normal wake cycle. This causes an afternoon crash.

No caffeine 10-12 hours before bed.
Read 10 tweets
Jul 13, 2023
In 2011, this guy created booking software for boat tours.

In 2018, he sold it for $300 million.

He kept all the money because he never raised a dollar.

The story of an amazing software business you've never heard of 🧵 Image
Meet FareHarbor.

Booking software that 20,000 tourism operators run on.

While other competitors raised $20-30 million rounds, they bootstrapped and doubled revenue every year.

They took a clever approach.

Let's dive in: Image
Problem

Brothers Lawrence and Zach Hester grew up in chilly Minnesota.

When Lawrence visited Zach at school in Hawaii, he tried to reserve a surfboard and kayak online.

He found there wasn't a simple way for these tourism businesses to accept online sales.

So they built it. Image
Read 13 tweets
Jul 1, 2023
Bryan Johnson spends $2 million a year to be 18 years old again.

In 2021, he reduced his epigenetic age by 5.1 years in 7 months (a world record)

His 13-steps for a long healthy life:
1. Results

In 2 years Bryan has achieved:

- 5.1 yrs epigenetic age reversal (world record)
- 100+ markers < chronological age
- Slowed his pace of aging by 31%
- Perfect muscle & fat (MRI)
- 50+ perfect biomarkers
- Fitness tests = 18 yrs old

An algorithm governs his life...
2. Approach

@bryan_johnson created Project Blueprint to be an algorithm to run his body.

Bryan doesn't make any decisions. He measures all 70+ organs through hundreds of tests & they govern his behavior.

30 doctors study the literature and test it on him.
Read 17 tweets
Jun 19, 2023
An ex-Googler built a $220m company by creating software for flooring stores.

They scaled to $10s of million in revenue in just a few years.

The wild story you've never heard of 🧵 Image
Broadlume is an all-in-one marketing and management platform for flooring retailers.

Today they have 3,500+ retailers on the platform.

But Broadlume started out as a very different business before a crazy pivot.
Meet Todd Saunders (@toddsaunders), the founder and CEO.

In 2015, Todd was working at Google helping companies grow with Google Ads.

They became great at optimizing accounts.

He left with a coworker to found AdHawk to help more companies optimize ads.
Read 14 tweets
May 19, 2023
The KING of search funds:

Will Thorndike

He has invested in 100s of business acquisitions.

His 6-point playbook for the best returns: Image
1. Ideal Business for Acquisition:

- Recurring revenue (60-80%)
- Low churn (<20% annually)
- Growing market 7+%
- Low capital intensity (ROTC 20+%)
2. Most Successful Business Models:

Often niche service (or software) businesses providing an essential service to a growing end market.

Ex: Asurian - roadside assistance company. Basically captive AAA.

One of the most successful search funds ever. Multi-billion $ company now.
Read 10 tweets

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