Colin Keeley Profile picture
Jul 1, 2023 17 tweets 6 min read Read on X
Bryan Johnson spends $2 million a year to be 18 years old again.

In 2021, he reduced his epigenetic age by 5.1 years in 7 months (a world record)

His 13-steps for a long healthy life:
1. Results

In 2 years Bryan has achieved:

- 5.1 yrs epigenetic age reversal (world record)
- 100+ markers < chronological age
- Slowed his pace of aging by 31%
- Perfect muscle & fat (MRI)
- 50+ perfect biomarkers
- Fitness tests = 18 yrs old

An algorithm governs his life...
2. Approach

@bryan_johnson created Project Blueprint to be an algorithm to run his body.

Bryan doesn't make any decisions. He measures all 70+ organs through hundreds of tests & they govern his behavior.

30 doctors study the literature and test it on him.
3. Avoid Self Destructive Behavior

Bryan sold Braintree for $800 million.

But he was 50 lbs overweight, depressed, and borderline suicidal.

He started with the basics. He stopped committing self-harm.

Stop:
- Overeating
- Eating poorly
- Skipping sleep
- Drinking too much
4. Diet Overview

Daily he eats:
- in a 6-8 hour window
- 1,977 calories
- 100+ pills
- 3 meals
- Vegan

He's vegan (except for collagen peptides) by choice. His head doctor and son do blueprint with meat.

This is a ~24% caloric restriction.

Total Food Cost: $44.91 / day
5. Wake Up Drink: Green Giant

• Water, 20 ounces
• Spermidine, 2 Tbsp chlorella powder
• Amino Complex 7.6g
• Creatine .5 g
• Collagen Peptides 20g
• Cocoa Flavanols 500 mg
• Ceylon Cinnamon 1 tsp

Cost: $9.91
6. First Meal: Super Veggie

• Black lentils 300 g
• Broccoli 250 g
• Cauliflower 150 g
• Mushrooms 50 g
• Garlic 1 clove
• Ginger 3 g
• Lime, 1
• Cumin, 1 Tb
• Apple Cider Vinegar, 1 Tb
• Hemp Seeds, 1 Tbsp
• Olive Oil, 1 Tbsp
• 100% Dark Chocolate, 1 Tbsp

Cost: $11
7. Second: Nutty Pudding

Malk Almond Milk 50 mL
Macadamia Nuts ground 3 Tbsp
Walnuts ground 2 tsp
Flaxseed ground 1 tsp of
Non-Dutched Cocoa 1 Tbsp
Sunflower Lecithin 1 tsp
Ceylon Cinnamon 1/2 tsp
Pomegranate Juice 2 oz
Brazil Nut 1/2
Berries 1 cup
Cherries 3

Cost: $11
8. Third Meal: Varies

Options:
- Asparagus Almond Beet Salad
- Stuffed Sweet Potato
- Orange Fennel Salad

Cost: $11

9. Supplements

Along with his meals, he takes 104 pills a day to round out his diet.

Goal is perfect nutrition. Calories available is a limitation.

Cost: $11.24 / day

10. Sleep

The most important longevity practice.

Sleep is a lighthouse. Bedtime never moves.

• Blue light-blocking glasses
• Temp-controlled mattress
• 1 hr downtime before bed
• Same bedtime daily
• Blacked out room
• Sleep alone
11. Fitness

Flex and stretch every muscle every day.

• 1 hr daily
• ~25 exercises
• 7 hrs per week

12. Skin

Daily:
• Face wash
• Other active creams
• Vit C, E, ferulic, B3, azelaic etc
• Cerave am face
• Cerave body
• Cerave pm face
• Tretinoin .1%
• UVA+B mineral sunscreen
• UV environmental filters
13. Daily Routine

• Green Giant + 54 pills
• One-hour workout
• Super Veggie
• Skin/oral/hair/eye care
• Travel to work
• Nutty Pudding
• Third meal + 34 pills

The process takes roughly 4 hours a day.
TLDR on Bryan Johnson's Longevity

- Avoid self-harm
- Exercise often
- Sleep well
- Eat clean

Start there and scale as far as you want.

Follow me @ColinKeeley for more breakdowns.

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More from @ColinKeeley

Nov 5, 2023
Hiring in the Philippines is dead.

LATAM hiring is the future.

The 6 biggest reasons:
1. Timezone

The biggest difference.

LATAM is just south of the US.

Argentina & Brazil are one hour apart from New York.

Filipinos say they are ok staying up all night working our time zone, but it takes a toll. They sacrifice sleep, and their work and life quality suffer.
2. Climate

The Philippines has extreme weather. Severe rains with floods knock out the internet and prevent them from working.

LATAM has a temperate climate and fast internet.

This also lets them make some great wine.
Read 8 tweets
Jul 16, 2023
Andrew Huberman is the #1 health scientist.

I’ve listened to 100+ hours of his podcast and interviews.

His 7-steps for a long healthy life: Image
1. Morning Sun

Get sunlight in your eyes first thing in the morning every day.

- No sunglasses
- 20-30 minutes is ideal
- Glasses / contacts fine
- Windows filter too much
- Artificial light if up before sunrise

Light wakes up your body & sets a timer for great sleep later.
2. Delay Coffee

Delay caffeine consumption for 90-120 minutes after waking.

If you drink it too early, it screws up your body's normal wake cycle. This causes an afternoon crash.

No caffeine 10-12 hours before bed.
Read 10 tweets
Jul 13, 2023
In 2011, this guy created booking software for boat tours.

In 2018, he sold it for $300 million.

He kept all the money because he never raised a dollar.

The story of an amazing software business you've never heard of 🧵 Image
Meet FareHarbor.

Booking software that 20,000 tourism operators run on.

While other competitors raised $20-30 million rounds, they bootstrapped and doubled revenue every year.

They took a clever approach.

Let's dive in: Image
Problem

Brothers Lawrence and Zach Hester grew up in chilly Minnesota.

When Lawrence visited Zach at school in Hawaii, he tried to reserve a surfboard and kayak online.

He found there wasn't a simple way for these tourism businesses to accept online sales.

So they built it. Image
Read 13 tweets
Jun 24, 2023
Peter Attia is the #1 longevity doctor.

He charges $150,000 a year to be his patient.

His 13-steps for a long healthy life:
1. Our Goal

Lifespan is the number of years you live.

Healthspan is how long you’re healthy enough to do the things that matter to you.

Longevity means maximizing healthspan and lifespan.

Our goal is to live longer and live better.

It all starts with prevention...
2. Avoid Icebergs

Medicine 2.0 (medicine today) deals with problems after they present themselves.

Medicine 3.0 focuses on prevention over cures.

We are trying to avoid icebergs in the distance.

It is better and easier to avoid the first heart attack than treat it after.
Read 16 tweets
Jun 19, 2023
An ex-Googler built a $220m company by creating software for flooring stores.

They scaled to $10s of million in revenue in just a few years.

The wild story you've never heard of 🧵 Image
Broadlume is an all-in-one marketing and management platform for flooring retailers.

Today they have 3,500+ retailers on the platform.

But Broadlume started out as a very different business before a crazy pivot.
Meet Todd Saunders (@toddsaunders), the founder and CEO.

In 2015, Todd was working at Google helping companies grow with Google Ads.

They became great at optimizing accounts.

He left with a coworker to found AdHawk to help more companies optimize ads.
Read 14 tweets
May 19, 2023
The KING of search funds:

Will Thorndike

He has invested in 100s of business acquisitions.

His 6-point playbook for the best returns: Image
1. Ideal Business for Acquisition:

- Recurring revenue (60-80%)
- Low churn (<20% annually)
- Growing market 7+%
- Low capital intensity (ROTC 20+%)
2. Most Successful Business Models:

Often niche service (or software) businesses providing an essential service to a growing end market.

Ex: Asurian - roadside assistance company. Basically captive AAA.

One of the most successful search funds ever. Multi-billion $ company now.
Read 10 tweets

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