Emmanuel Profile picture
Sep 7 7 tweets 2 min read Twitter logo Read on Twitter
Is SARS-COV-2 a BACTERIOPHAGE ? 😨
(2nd part - layman terms)

"The secrets of SARS-COV-2" Image
2) In the first part, I posted the study by Carlo Brocha and his colleagues "Could SARS-CoV-2 Have Bacteriophage Behavior ..."

In 2001, Carlo gave an absolutely AMAZING INTERVIEW to an Italian newspaper.
(Big thanks to @popolux4)
affaritaliani.it/coronavirus/va…
3) I can’t resist the pleasure of sharing a few excerpts from this interview 👇

Sars Cov 2 enters bacteria and this changes everything :
"Sars Cov 2 is also a bacteriophage virus. It means that it enters bacteria and replicates its RNA from there too."
4) "A virus normally attacks our cells, i.e. the epithelium and mucous membranes.
Try to enter and replicate and this induces an immune response in the host."
"In the case of a bacteriophage virus, it does not pass without interfacing first with the microbiome,
5) ... but also enters the bacteria."
"Since he is also a bacteriophage, one must accept the evidence that is everywhere. Colonize sewers, waters, seas."
"Contact and orofecal transmission represents another explanation for the continuous increases in positives."
6) "How many waves does it foresee? The bacteriophagic nature of the virus is not well inclined. We will have, perhaps, three a year with many mutations."
"We will also need a vaccine against the toxins that we have found and produce our bacteria ...
7) ... in a way very similar to the diphtheria mechanism."

I recommend his book which you can buy online.
Thanks for reading 🙏

FYI
@DavidJoffe64 @LauraMiers @HarrySpoelstra @MeetJess
@RadCentrism @C_A_Gustave @arijitchakrav @mrmickme @outbreakupdates @1goodtern
@xabitron1

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More from @ejustin46

Sep 9
IMMUNE IMPRINTING
(mega🧵)

After someone encounters a virus for the 1st time, through infection or vaccination, the immune system remembers its initial response in a way that usually weakens the response to future variants of the same pathogen but may sometimes strengthen it Image
2) Immune imprinting process Image
Read 11 tweets
Sep 8
VARIANTS, CLOUD, SWARM, QUASISPECIES 🤔

You just have to look at the latest publication of the variants in the UK 👇, to understand that we cannot use the same words, to describe what happened since few months Image
2) "MUTANT CLOUDS"

It is in the late 1970s that the virologist Esteban Domingo discovered that a single virus produces an array of daughter viruses that are almost, but not quite, identical. Every generation spawns another array of viruses ... Image
3) ... leading to what Domingo called a “mutant cloud” of viruses.

The term "variants soup" was still very approximate as we have said on several occasions. scientificamerican.com/article/how-mu…
Image
Read 11 tweets
Sep 6
Is SARS-COV-2 a BACTERIOPHAGE ? 😨 Image
2) We had already mentioned, in several threads, the risk of co-infection bacterial and COVID-19, whether for respiratory bacteria ... 👇
nature.com/articles/s4142…
Image
3) ... or in interactions and alterations of the gut microbia and the risk of promoting other types of bacterial infections
nature.com/articles/s4139…
Image
Read 8 tweets
Sep 5
MULTI-OMICS profiling reveals phenotypic and functional heterogeneity of NEUTROPHILS in COVID-19

SUMMARY (layman) :
Neutrophils are a type of white blood cell that play a crucial role in our immune response. Multi-omics profiling refers to the use of ... biorxiv.org/content/10.110…
Image
2) ... different techniques to study various aspects of these cells simultaneously, such as their genetic makeup, gene expression, and protein levels.
In the context of COVID-19, multi-omics profiling has shown us that neutrophils are not a uniform population. They exhibit ... Image
3) ... phenotypic and functional heterogeneity, meaning that there are different subtypes or variations of neutrophils with diverse characteristics and functions during the course of the disease. This heterogeneity can have implications for disease severity and patient outcomes. Image
Read 5 tweets
Sep 1
KEY STUDY !
"Alterations in innate immune phenotypes and epigenetic programs of HSPC persisted for months to 1 year following severe COVID-19"
cell.com/cell/fulltext/…
Image
2) Graphical abstract Image
3) Altered chromatin accessibility and durable epigenetic memory in monocytes following COVID-19 Image
Read 12 tweets

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