1. Time-restricted feeding (8-hour eating window), as compared to normal feeding (12-hour eating window) decreases fat mass and maintains fat-free mass, while not affecting running performance, in trained male endurance runners. 2. Time restricted eating (TRE) results in a significant change in body composition with whole body fat mass, leg fat mass, and percent body fat declining more in the TRE intervention, with no change in fat-free mass. 3. TRE does not result in any significant differences in resting energy expenditure, markers of insulin resistance, serum lipids or blood pressure, as compared to normal feeding group. 4. Maximum oxygen uptake (VO2max) increases significantly after TRE. A possible explanation for the improvements in VO2max with TRE includes an increase of cardiac output due to an increase of sympathetic stimulation during exercise or a greater oxidative capacity in fat adapted muscle. Ultimately, the combination of these phenomena may lead to improvements in aerobic performance. 5. In a group of active women, high intensity interval training (HIIT) and HIIT+IF interventions resulted in a reduction in the percentage of body fat of −0.3% and 1.0%, respectively. HIIT+ IF combination also results in a significant reduction in waist circumference (WC). 6. Women in HIIT+IF group also had a better jumping performance as compared to women who did HIIT without IF. 7. Duration of IF & running (or exercise) also matters. Benefits may not be seen within 4-6 weeks; however, benefits are definitely seen if running + IF is practiced for 12 weeks or longer.
Summary of findings & recommendations 1. Exercise in a fasting state decreases body weight, free fat mass and fat mass. 2. Exercise is relatively safe, if fasting duration is less than 24 hours, 3. Running up to a distance of 10 Km is reasonably safe for most people, if fasting duration is less than 24 hours. 4. Trained athletes could run up to 2 hours (a half marathon), if the duration of fasting is <24 hours. 5. Distances more than half marathon should be avoided if the period of fasting is >24 hours. 6. It may not be a good idea to go for your best pace, after a fasting for longer than 24 hours. 7. Adequate hydration should be maintained while exercising in a fasted state. 8. Those practicing intermittent fasting (16/8) could prefer to run in a fasted or a fed state. For example, if the eating window is from 8 AM to 4 PM, one could run at 6 AM (fasted state) or 6 PM (fed state) depending on his/her preference and the running distance planned.
#running #fasting
Dr Sudhir Kumar MD DM X (Twitter): @hyderabaddoctor
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What is insulin resistance and how to determine (calculate) it? youtu.be/hpW9nBQFgX0?si…
➡️Even if your fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1C) are normal, it may not mean that everything is normal.
➡️Prediabetes: FBG between 100-125 mg/dL or HbA1C between 5.7 and 6.4 is referred to as prediabetes. People with prediabetes have a higher risk of developing type 2 diabetes and cardiovascular diseases.
➡️Insulin resistance can occur even if FBG and HbA1C are within normal limits.
➡️HOMA IR (Homeostasis Model Assessment Insulin resistance) can be obtained if you have serum insulin and FBG values. HOMA IR above 2 is suggestive of insulin resistance.
➡️Triglyceride/HDL cholesterol (TG/HDL-C) ratio above 2 is considered a surrogate marker of insulin resistance.
➡️Triglyceride Glucose (TyG) index above 4.7 is also a surrogate marker of insulin resistance. If your blood tests reveal insulin resistance, discuss with your physician and nutritionist.
➡️Lifestyle measures such as healthy diet, regular exercise and reduction of weight if overweight or obese can help in improving insulin sensitivity in most cases.
Running is better than walking for insulin resistance (personal experience=anecdotal or Class 4 evidence)
➡️I had switched to walking since May 2024 due to flare up of ankylosing spondylitis. Weekly mileage: 35-40 Km
Blood test reports (Sep 2024)
Serum Insulin- 19.8
Fasting Glucose- 95
HOMA- IR: 4.6
HbA1C- 5
➡️I restarted running from Dec 2024. (Weekly mileage 35-40 Km)
Blood test reports (Feb 2025)
Serum Insulin- 10.8
Fasting Glucose- 92
HOMA- IR: 2.5
HbA1C- 4.3
➡️There was no other change in lifestyle: diet, working & sleeping hours remained same.
➡️Other metabolic parameters, such as weight, Waist circumference, BMI, and lipid profile parameters did not show any significant change (between Sep 2024 and Feb 2025).
Take home message
✅Running is superior to walking for reducing insulin resistance (or improving insulin sensitivity).
(As stated earlier, this is a personal experience of one person, and therefore, the findings are not conclusive).
There are two other ways of measuring insulin resistance: 1. Triglyceride/HDL Cholesterol ratio (TG/HDL ratio) 2. Triglyceride Glucose index (TyG index)
Sep 2024 1. TG/HDL ratio was 1.49 2. TyG index was 4.42
Feb 2025 1. TG/HDL ratio is 1.72 2. TyG index is 4.43
(Reference for cut-off values below is from a small study in South India- Madurai) doi.org/10.7759/cureus…
Why you should NOT reheat your tea and drink?
We all enjoy a hot cup of tea. Sometimes, if one is unable to have tea on time, and it gets cold, tea is often reheated and served. But this practice is unhealthy. Here are the 5 reasons:
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1. Polyphenols and other bioactive compounds in tea can get damaged with repeated heating, thereby reducing their antioxidant properties.
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2. If tea is left for more than 4 hours at room temperature, there is a risk of bacterial growth. Reheating is not enough to get rid of this bacteria, thereby increasing the risk of gastrointestinal infection.
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Short Story of a minor Struggle and Successfully overcoming it
May 2024
Flare up of ankylosing spondylitis (AS), caused pain in multiple joints, tendons and ligaments.
Sudden break on running after three and half years.
Even walking was difficult- every step was painful.
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Waited for a day or two for pain to reduce/subside; as that was the norm earlier (during the past 34 years, after the most severe relapse in 1990, when I was hospitalized for more than three weeks at CMC Vellore).
Pain did not reduce, instead, it became more severe.
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Consulted a rheumatologist and an orthopedic surgeon;
Investigations confirmed a relapse of AS (enthesopathy, tendinopathy, joint inflammation, etc)
Was suggested complete rest; pain-relief medications and specific medications (biologicals) for AS.
This appeared depressing..
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Running as a form of aerobic exercise increases longevity, but there are other factors to consider too.
The news of Jogi ji's passing away due to cardiac arrest during sleep is shocking. Our heartfelt condolences🙏
1. Joginder Chandna ji was extremely fit and had amazing statistics for a long-distance runner. His PB for 5k, 10k, HM and FM were 23 min, 46 min, 1:39 hours and 3:40 hours.
2. He had an amazing control over heart rate while running long distances. His latest long run (23 Km) was on Sunday, 28th July (2 days before we lost him). An AHR of 127 bpm (and a max HR of 139 bpm) for a pace of 6:50 min/Km is amazing.
3. His running mileage was not excessive. If we look at his last 12 months, his monthly running mileage ranged from 170-240 Km (which translates to 6-8 km per day, or 50-60 Km per week). This is within the safe zone as per research.