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Emmanuel

@ejustin46

Oct 6, 2023 • 12 tweets • 5 min read • Read on X

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SARS-COV-2 for KIDS 👩‍❤️‍👨
IMMUNITY, the lines of defense against the virus ...
(with amazing videos)

2) A short introduction ...

2) From the start of the infection, our body will react with a certain number of lines of defense

3) In term of innate immunity, there are, before the interferons, the toll-like receptors (TLRs). To keep it simple, due to the complexity of this subject, we propose you a brief discovery with this video

4) It is these receptors which will trigger interferons and cytokines.
Interferons are a group of proteins, which work by inhibiting the replication of viruses and stimulating the immune system to mount a defense against the infection

5) Cytokines are a broad category of small proteins or peptides that are involved in cell signaling. They regulate various aspects of immune responses, including inflammation, cell growth, and cell differentiation.

6) We will return later to this important subject of the manipulation of interferons by SARS-COV-2.
In a defective immune response this leads to further accumulation of immune cells, causing overproduction of pro-inflammatory cytokines, a "cytokine storm" ..

7) ... which damages the lung infrastructure and circulates to other organs, leading to multi-organ damage. COVID-19 is a multisystem inflammatory disease.

8) Finally, there is what we call the adaptive immunity, composed of humoral and cell-mediated immunity.

9) It is thanks to these adaptive immunity mechanisms that for example the CD4+ T-cells helpers or the antibodies will be produced.

10) In conclusion, for those interested, we had already posted a thread for kids.

https://twitter.com/ejustin46/status/1645022922489069568?t=UI0is16umofS4bmbAb5liQ&s=19

11) Thanks for reading 🙏
REFERENCES.
Studies

Video :
FYI
@MeetJess @LauraMiers @DavidJoffe64 @RadCentrism @HarrySpoelstra @1goodtern @outbreakupdates @UseBy2022 @mrmickme @RolandBakerIII
@AltenbergLee nature.com/articles/s4157…
nature.com/articles/s4159…
proteinlounge.com/animation_deta…

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Emmanuel

@ejustin46

Nov 6

**THE AGE OF PANZOONOTICS**

In the world of infectious diseases, panzoonotic diseases stand out for their ability to spread between multiple animal species and from animals to humans, revealing our interconnectedness.

What MAKES COVID-19 a UNIQUE PANZOONOTIC?

https://x.com/ejustin46/status/1814701079432401114?s=19

2)To grasp this, we must acknowledge the major panzoonotics that have influenced public health: Rabies (spanning 190 species) , COVID-19 (58 species), and avian influenza (48 species).
While COVID-19 is prominent, other diseases ...

https://x.com/ejustin46/status/1814701079432401114?s=19

3)... like Ebola or Zika illustrate this complex transmission. Bacterial panzoonotics, such as brucellosis or leptospirosis further emphasize the diverse threats we face.

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Emmanuel

@ejustin46

Nov 6

The FALSE FRIENDS and MISCONCEPTIONS about COVID-19

COVID-19 is a winter virus? Apparently, June 2025 was winter in the UK! Who knew?

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Emmanuel

@ejustin46

Oct 21

What Are the KEY DIFFERENCES That Make SARS-CoV-2 UNIQUE Among RESPIRATORY VIRUSES Like INFLUENZA and RHINOVIRUSES?

▶️ TRANSMISSION MECHANISM :
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2) ...which can lead to asymptomatic spread.
- **Influenza**: Also spreads via respiratory droplets, but typically has a shorter contagious period and less asymptomatic transmission compared to SARS-CoV-2.

3) - **Rhinoviruses**: Mainly spread through direct contact and respiratory droplets but are often more localized to the upper respiratory tract.

▶️ INFECTIOUS DOSE:
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Emmanuel

@ejustin46

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SPERM, STRESS, and the NEXT GENERATION:
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2) We had already warned several times about the risks of COVID-19 on sperm.

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Emmanuel

@ejustin46

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IS SARS-CoV-2 BECOMING "INVISIBLE"? The Hidden Truth Behind the Pandemic

As the world strives to move past the COVID-19 pandemic, a troubling narrative has emerged: the perception that SARS-CoV-2 is becoming "invisible."

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2) Governments and communities are eager to return to normalcy, leading to a tendency to downplay the virus's severity. Reports of new infections and long COVID cases have been totally minimized, creating a false sense of security ...

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3) ...that the virus is no longer a significant threat. However, this perception is not only a matter of public sentiment. The virus itself has evolved, most notably with the emergence of the Omicron variant. Recent research reveals that Omicron exhibits a remarkable ability ...

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