AJ Leonardi, MBBS, PhD Profile picture
Oct 14, 2023 10 tweets 5 min read Read on X
Since 2020 I have claimed that sars cov 2 infection would create harmed t cell memory based on phenotypes after infection

It is now proven

Even so, I have several Professors who pretend to not understand or do not understand how, nipping at my heels

I assume they behave this way because they are tenured & very mad, so they feel they can put their ignorance and vitriol on display wantonly

Bertoletti even made a nod to me in a publication, which the journal maintains references me in no way whatsoever


Image
Image
For their benefit, I will list the publications that prove my thesis correct:

The first is how T cell responses derived from vaccination are superior to those derived from infection. T cell functions after infection were harmed. The publication is below:
The second proof is how people who were infected risked reinfection shortly afterward. That publication is here:


Image
This is consistent with the third publication, which shows the dampened CD8 T cell responses following infection. That publication is here:
Image
To address Kasper's category error: faster pcr negativity of a sars cov 2 infection upon reinfection is not proof that T cells or immunity have not been harmed.

Antibodies and b cell memory are largely contributing to clearance as well

You can look at t cells directly Image
The paper from the Danish Government is extremely poor and political

It claims people infected with cov 2 have less chance of infections with other illnesses, despite confessing how this is unexpected given derangements in the immune system following infection
Image
Image
It also fails to repeat observed increases in other infections like tonsillitis after sars cov 2, which is another weakness this paper acknowledges

It is very poorly designed Image
In fact, we know a common post-viral complication is a bacterial pneumonia

The study could not reveal this, and in fact showed the opposite; that sars cov 2 protects

How could any conclusions be reliably drawn from the paper? It is poor science on parade. Image
It is not the only poorly designed paper

Some epidemiology studies have been designed where they sample a population biased by some metric, including age or working status

They are massaging the epidemiology

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with AJ Leonardi, MBBS, PhD

AJ Leonardi, MBBS, PhD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @fitterhappierAJ

Jun 22
@Bryce_Nickels This is absolutely false because he made a “noble lie” and said the N 95s would not work for the public to the public in order for there to be greater supply to healthcare workers only. This backfired.
@Bryce_Nickels The ethical approach was the truth. This is a similar noble lie by omission that the WHO made when they refused to declare Covid as airborne in order for impoverished health systems to provide “adequate” PPE per their regulations according to WHO standards
@Bryce_Nickels The end result was workers in impoverished systems were being given “adequate “PPE for droplet transmission, and many of them died, including sadly many in New York City.
Read 4 tweets
Apr 6
When will H5N1 will go Human to Human?
Which is deadlier?
"The Covid pandemic has prepared me for an H5N1 pandemic"
Read 4 tweets
Mar 29
I think the decrease in childrens performance following 2020 was due to the Neurological harm after they were coaxed into unsafe classrooms before vaccination

I think this will remain the dominant effect due to Covid's neurotropism on reinfection

theconversation.com/mounting-resea…
Some people are encouraged to obfuscate the risk of kids getting infected and they will continue to do so


Image
Image
16.1% of reinfected children got Long covid after reinfection compared to 12.1% with only 1 infection

More reinfected individuals had persistent anosmia, an indicator of neuroinflammation
ncbi.nlm.nih.gov/pmc/articles/P…
Image
Read 4 tweets
Jan 26
I was a fellow at the National Cancer Institute for 4 years in immunotherapy of cancer

They paid for my PhD

I am happy to explain hypotheses for a potential SARS Cov 2 based increased risk of cancer:

1/4
There are multiple ways a virus can cause cancer directly & indirectly

One indirect way is by tempering immunity

The immune system surveils for wayward, cancerous, and precancerous cells, and kills them

SARS Cov 2 ages & dysregulates T cells
2/4
A second broad yet direct category is by Viral Oncogenes or mutagenesis

Some Viruses have proteins that can change expression or function of host genes & accelerate the formation of tumors by preventing cell death

Some viruses cause DNA errors to accumulate
3/4
Read 5 tweets
Jan 24
In 2021 on TWIV, Vincent Raccaniello said my claims of T cell exhaustion risk were "Twitter Science™"

In 2024 I am pleased to see T cell exhaustion is Science™, Nature Immunology™, and Nature Medicine™ Science
Raccaniello is arrogant enough to the extent to reject an accurate scientific hypothesis on twitter and his TWIV podcast to the detriment of the public, without knowing enough about the subject It was completely irresponsible

Are you feigning ignorance? It was a perjorative.
Read 10 tweets
Jan 23
Massachusetts General Hospital has declared a critical incident under a "capacity disaster"

Some professors at Harvard assured the crisis phase of covid was over.

I sure would be embarrassed if shown up by someone I keep proclaiming superiority over.

patch.com/massachusetts/…
Especially if I was a wunderkind Harvard professor in Cardiology.

That would mean I know at least as much immunology as a professor of immunology at a state school
Which Mark has the better takes in immunology?
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(