Bryan Johnson Profile picture
Dec 11, 2023 6 tweets 6 min read Read on X
My former fiance threatened to make fabricated and scandalous public accusations about me unless I paid her $9 million in one week. Two years later, a Judge ordered her to pay me $584,199.16 for fees I spent defending my innocence.

It started on April 6th, 2021 with a thirteen-page letter from her lawyers: “[Redacted] is willing to settle all of her claims against Mr. Johnson and his companies for $9 million dollars…”. After over a year of our relationship ending, for the first time ever, she was accusing me of a wide range of “abusive and perverse” behavior. Through her attorneys, she threatened to make her allegations public if I didn’t pay her $9 million dollars within one week.  WTF? What claims? What wrong-doing? It must be April Fools. Am I getting punked? This person who I’d once had the most beautiful relationship with was now unrecognizable to me.

The contents of the letter were shocking, but even more shocking was the fact that this letter was arriving after we had signed a separation agreement (with the help of our attorneys) a year earlier when ending our relationship. She and her attorneys were gambling that, even though she had already agreed that we’d go our separate ways, I'd cave and pay up to avoid my reputation being publicly tarnished.

She was emboldened by lawyers blinded by their greed to take advantage of her vulnerabilities and exploit my wealth. After over six months of threatening to destroy me with more scandalous allegations in “her new podcast”, a “book deal” and a “potential TV series”, the attorneys who sent the demand letter never filed a complaint or produced a single piece of evidence to support the allegations.

Then she got new attorneys. Seeing that threats alone were insufficient, they filed a case in court and tried to make me look like a monster.  I successfully moved part of the case into arbitration, where we had agreed to resolve any disputes. As their legal losses mounted, they became increasingly unhinged in what they were willing to say. Global media ate it up.

On March 31st, 2023, after extensive motions, depositions and discovery, the arbitrator dismissed all her causes of action that had been referred to arbitration and ordered that my accuser pay me $584,199.16 to reimburse attorneys' fees I’d been forced to spend defending my innocence. The ruling and award were confirmed by an active Superior Court Judge on September 29th, 2023.

After years of litigation, the corroborating evidence my accuser had of any of my accused wrongdoings?  Nothing. Not a single thing. In considering my accuser’s attempt to invalidate the separation agreement she had signed, the arbitrator, a well-respected retired judge, pointed out that my accuser’s “undisputed conduct and testimony refute her claim[s].” In other words, my accuser's own evidence contradicted her own story. Noteworthy as my accuser’s day job is Chief Storytelling Officer at an implantable medical device company where trust is life and death.

The entire thing was bizarre and surreal. My accuser's attorneys were sanctioned by the Judge - a severe reprimand that courts reserve for truly egregious conduct - for making, as the Judge wrote: “serious allegations…factually and legally baseless and frivolous”. Her lawyers were ordered to pay the court a fine of $2,500.  In our settlement discussions, I also insisted her attorneys pay some of what my accuser owed to me for their complicitness.

It would have been so easy to relent and quietly settle to make this go away. That’s what nearly everyone does. But I am not guilty and they gave me no choice but to spend over two years litigating to prove my innocence. Giving in and paying up would have been an injustice to me; an injustice to society enabling this twisted practice.

The legal fight was ugly and awful. The worst. The most hurtful part of the whole ordeal was that she spoke about our relationship in ways that were unrecognizable to me. For example, when she was sadly diagnosed with a serious health condition, I rearranged my life and worked non-stop beside her to beat it. We flew around the country together to meet with doctors and explore clinical trials.  Together we conducted extensive research into additional therapies and tests. It was our shared omnipresent focus. When tests showed that she was in the clear and it was time to celebrate her new lease on life, who was the one person in the world she invited to be by her side at this sacred event?  Me. She honored my unwavering devotion to her well-being.

The case is now wrapped and behind us. This time with a promise that she won’t sue me again, a provision the previous agreement didn’t have and which allowed her and her attorneys to weaponize the legal system for over two years. Their strategy was to inflict maximum pain and suffering on me so I’d pay up privately. They miscalculated my tenaciousness and resolve and their strategy backfired, inflicting collateral damage upon themselves. One of her attorneys is no longer with that firm and my accuser’s health deteriorated within the blast radius of her own creation.

My accuser has been astonishingly pernicious. Nonetheless, I choose, again, to support her as she works through her health challenges. The settlement funds she owes me will be routed to a trust I established for her medical needs. She is the sole beneficiary and the only person who can access this trust. I won’t keep a penny of what she pays me as part of the judgment.

Every minute of every day each of us diligently works to build and fortify our personal reputations. Showing up on time. Being respectful. Offering sympathy. Helping out. Apologizing when at fault. Telling the truth. Our reputation is our life currency. Then, in one moment, a headline can cause everyone you love and care about to question everything they thought they knew about you. A lifetime of work now in question. It’s great entertainment when it’s about someone else; a different thing when it’s your name in the headline.  It’s been no fun having my name dragged through the mud and not being able to comment during the proceedings.

“Innocent until proven guilty” is a bedrock of our society. In recent years, accusations have been weaponized and exploited for profit as “guilty until proven innocent” became de facto by mob rule. Ruining people’s careers, lives and reputations. Taking away from those who legitimately need the legal system. It has created a booming, dark underground economy that has destabilized society by straining our bonds of trust.

Our social fabric is fragile; woven together by a shared trust. The accusation strategy she used is corrosive to our shared stability. I hope more people stand up to this dark and twisted practice.
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Endnotes:
Before the Apr '21 thirteen page scorched-earth letter from her attorneys, my accuser's first tactic to get money from me was a letter she penned in Sep '20. She praised my integrity, spoke of our shared love, & emphasized the reciprocal care we’d show for each other.
When that didn’t work, she and her attorneys sought to disparage me and create scandal.  As their legal losses mounted, they became increasingly unhinged in what they were willing to say. For example, by accusing me of bribing the arbitrator. Trying to embarrass and pressure me into private settlement. As my court filing put it:
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The Judge wasn’t having their bribery fiction. She found that the attorneys “acted with reckless disregard for the truth and the law in making the accusations” and “violated” their “duties of respect and honesty.”  The Judge severely reprimanded the attorneys for making “frivolous” claims with “no evidence” to support them, “undermin[ing] the dignity and integrity of th[e] court’s proceedings.” She sanctioned the attorneys $2,500.
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Press, why do you gotta be like this? Image
watch:
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More from @bryan_johnson

Nov 11
I'm exploring magic mushrooms as a longevity therapy.

Sunday was my first dose: 4.67 grams of dried Psilocybe cubensis (B+ strain), containing 24.98 mg of psilocybin.

Here is an overview of the current scientific evidence:

Longevity
Psilocybin extended lifespan in mice and preserved telomeres in human cells, first evidence linking psychedelics to longevity.

Inflammation
A single psilocybin dose reduced TNF-α, CRP, and IL-6. Systemic inflammation markers tied to aging.

Neuroplasticity
Psilocybin increases brain entropy, breaks rigid patterns, and boosts long term cognition and flexibility.

Clinical outcomes
Psilocybin activates 5-HT2A receptors to reduce neuroinflammation, protect neurons, and may slow neurodegeneration.

Gut-brain axis
Psilocybin may reshape the gut microbiome. Potentially influencing serotonin, immunity, and mood.

Sexual health
Two studies show psilocybin improved sexual satisfaction and communication in people with depression.

More detailed explanations are below.Image
1/ Evidence of psilocybin extending mammalian lifespan (mice) and cellular lifespan (human fibroblasts in cell culture).

Psilocin, the active metabolite of psilocybin, has been shown to preserve telomere length, prevent attrition, and increase replicative lifespan in human fibroblasts in cell culture. The same study reported that psilocybin reversed senescence markers and extended the remaining lifespan in old mice.

In human fibroblasts in culture: treated with 100µM psilocin (the active metabolite of psilocybin)

+ Increased Doubling Divisions: 29% and 51% increase in doubling divisions with 10µM and 100µM psilocin, respectively, with no signs of carcinogenicity (no immortalization; all cells eventually ceased dividing).

+ Telomere Length Restoration: Over 50% increase in telomere length compared to control in aged cells.

+ Reduced Senescence Markers: Over 40% reduction in the key senescence marker B-Gal in aged fibroblasts, along with cell-cycle arrest markers p16 and p21.

+ Upregulated Gene Expression: Upregulation of DNA repair and anti-oxidant gene expression (Sirt1, PCNA, Nrf2), and a dose-dependent decrease in reactive oxygen species (ROS).

While more evidence is needed as these markers for cellular longevity in human cells do not necessarily translate to in-vivo gains in humans, the authors also provided another compelling piece of evidence: lifespan extension in older mice.

In mice: monthly dose of 15mg/kg (equivalent to a human dose of 25mg, after multi-factor adjustment)

+ 30% Increase in Survival Odds to Very Old Age: Starting at 19 months (the mouse equivalent of 65 human years), a once-monthly oral dose of 15mg/kg (equivalent to a high human dose of 25mg) increased the odds of surviving up to 28 months (equivalent to 80+ years in humans) from 50% to 80%.

+ Healthspan Hints: Treated mice maintained sleeker coats and regrew fur with fewer white hairs. Hair regrowth and pigmentation are common proxies in longevity research, offering an early hint of a general increase in health and vitality alongside lifespan gains.Image
2/ Single-dose psilocybin acutely and persistently reduces systemic inflammation markers in humans, and in human intestine 3D organoids.

A clinical trial involving 60 healthy participants (30 psilocybin, 30 placebo) demonstrated that a single, relatively high dose (0.17mg/kg) of psilocybin led to immediate reductions in TNF-alpha, with further reductions in CRP and IL-6 observed seven days post-dosing.

In an intestinal 3D culture model, used for studying inflammatory bowel diseases, psilocybin treatments (10 and 20 µM) reduced the pro-inflammatory markers TNF-a, INF, IL-6, and IL-8.

Psychedelics including psilocybin, LSD, and DMT all mitigate neuroinflammation by activating the 5-HT2A receptors leading to a decrease in pro-inflammatory cytokines, microglial modulation and a shift from neurotoxic to neuroprotective metabolites.Image
Read 8 tweets
Oct 21
I eliminated 85% of microplastics from my ejaculate.

Nov 2024: 165 particles/mL
July 2025: 20 particles/mL

Nearly identical drop in my blood same time period:
Oct 2024: 70 particles/mL
May 2025: 10 particles/mL

Important as a meta-analysis of 36 studies reveals that microplastics induce oxidative stress in the male reproductive system, leading to testicular inflammation, cell death, and reduced testosterone levels, sperm production, and motility.

Two studies last year showed that microplastics were detected in every human testicular and semen samples tested.

The therapy we think most responsible for this reduction is sauna as it also eliminated most environmental toxins in my body, including those linked to various plastics (200 F, 20 min daily w/ ice on the boys). I also avoid the big no-no’s like microwaving in plastic, plastic cutting board, and having a reverse osmosis water system.

To our knowledge, this is the first report of any correlation (esp in the same person over two timepoints) between blood and semen microplastic levels, demonstrating successful microplastic detoxification in the semen following that in the blood.Image
1/ My results offer a new sense of hope for the detoxification of microplastics from the testis and semen, especially after the concerns raised by a study last year.

To our knowledge, this is the first report of any correlation (especially over two timepoints) between blood and semen microplastic levels, demonstrating successful microplastic detoxification in the semen following that in the blood.

This is encouraging news, as recent reports of microplastic accumulation in the testis have specifically raised concerns about microplastics accumulating in reproductive tissues, with the reversibility of such accumulation being uncertain.

Earlier last year, a study made headlines by reporting high levels of microplastic particles in the testicles of deceased humans and dogs. Microplastics were positively detected in every tested sample at average concentrations of 328.44 µg/g and 122.63 µg/g, corresponding to approximately 5.9 x 10¹¹ and 2.2 x 10¹¹ micro- and nanoplastic particles per gram of testicular tissue (1µg ≈ 1.8 x 10⁹ particles).

It is important to note that this is a rough estimate, as this number converts all detected microplastic molecules to particles, while some plastic material might also exist in dissolved monomeric or oligomeric forms. These figures roughly correspond to 2.2 x 10¹¹ and 5.9 x 10¹¹ particles/g, depending on the size and type of the microplastic particles.

An earlier study reported a lower number of microplastic particles per gram of testicular tissue and 0.23 particles/mL of semen. However, this study likely underestimated the numbers due to a high cut-off size.Image
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2/ Similar correlations have been observed for plastic leachables, but never for microplastics, and never longitudinally over time with effective mitigation interventions.

Earlier studies showed correlations between serum, blood, and urine for some plastic leachables, including BPA and some phthalate metabolites. However, these were single-time point studies with no longitudinal follow-up or mitigation interventions.

BPA levels in semen correlated with blood levels and lower semen motility. Microplastics in semen can also leach BPA and other chemicals, in addition to their direct mechanical disruption of testicular tissue, triggering a range of oxidative, inflammatory reactions, and hormonal and endocrine disruptions.Image
Read 5 tweets
Sep 3
My 4+ hour daily routine resets my blood vessels to perform like they did in my teenage years. 🧵 Image
0/ Here is the level of vascular function reset and rejuvenation enabled by my morning routine, every single day

+ Central blood pressure: 86 mmHg (lower than 99% of males < 20)
+ Peripheral blood pressure: Systolic 94/ Diastolic 56 (lower than 99% of males < 20)

+ Vascular elasticity and compliance (softness):
a) Augmentation pressure: -1 mmHg (lower than 50% of males < 20)
b) Augmentation index: -4% (lower than 60% of males < 20)
1/ I previously shared that my sauna protocol has restored my vascular function and blood flow to levels typical of a healthy 20–25 year old. This effect has been observed consistently, whether the readings are taken upon waking or later in the day.

However, my morning routine, which combines exercise sauna, red/NIR light therapy, and HBOT or IHHT, takes this to the next level.

Daily, it guides my arteries and vascular system into a state of relaxation, akin to a soothing massage for your blood vessels.

Here’s what we’ve noticed and how it unfolds:
Read 6 tweets
Aug 31
This is big. OpenAI and Retro used a custom model to make cellular reprogramming into stem cells ~50× better, faster, and safer. Similar Wright brothers’ glider to a jet engine overnight.

We may be the first generation who won't die.

Let's take a look at what they did. 🧵 Image
0/ AI Redesigns the Engines of Cellular Reprogramming

OpenAI and Retro Biosciences reported a landmark achievement: using a domain-specialized protein design model, GPT-4b micro, they created engineered reprogramming factors that deliver over 50× higher efficiency in generating induced pluripotent stem cells (iPSCs), with broad validation across donors and cell types. These AI-designed proteins not only accelerate reprogramming but also enhance DNA repair, overcoming DNA damage as one cellular hallmark of aging hinting at relevance for aging biology.
1/ 0/ From Yamanaka’s Discovery to Today

In 2006, Shinya Yamanaka identified four transcription factors; Oct4, Sox2, Klf4, and c-Myc (OSKM), capable of resetting differentiated adult cells into a pluripotent, embryonic-like state. This breakthrough opened two revolutionary doors in biology:

1) Full reprogramming: completely erasing cell memory, identity, to generate pluripotent stem cells (iPSCs) for regenerative medicine, tissue engineering, and disease modeling.

2) Partial reprogramming: transient expression to roll back cellular age without erasing cell identity.

This remarkable discovery won Yamaka the Nobel Prize for Physiology or Medicine in 2012.

Yet, in practice, OSKM are astonishingly inefficient (<0.1% conversion, requiring +3 wees of culture) and carry oncogenic risks, particularly from c-Myc. These limitations have long restricted their therapeutic potential. These limitations have limited the progress in regenerative medicine due to the difficulty of scaling the safe and reliable production induced pluripotent stem cells.Image
Read 6 tweets
Aug 29
I sacrificed my fertility for this message:
ice your balls in the sauna

After icing improved my fertility markers,
I removed the ice to validate

The boys suffered. More than we initially thought.
Here’s my latest results explained. 🧵 Image
0/ Results from sauna experiment

27 daily sauna sessions with ice on balls:
+ total motile count ↑ 57%
+ motility ↑ 16%,
+ total count ↑ 43%

2 weeks without icing (15 sauna sessions with full heat on balls)

my boys’ motility decreased, counts unaffected
total motile count ↓ 54%
motility ↓ 57%
total count ↑ 6%

direct hit to motility and total motile count due to mature sperms in storage (sperm is stored for a couple weeks between full maturation and ejaculation in the Epidimysis).Image
1/ One week post re-icing: misleading partial recovery (values compared to pre-sauna baseline)
total motile count ↓2%
motility ↓ 34%
total count ↑ 56%

4 weeks post re-icing: 2nd wave of heat effects: large drop in count, motility.
total motile count ↓ 56%
motility ↓ 50%
total count ↓ 9%

Latent hit to counts and motility:
heat damages early spermatogenesis (meiosis) and later sperm maturation (morphological changes, tail formation, and cytoplasmic loss) leading to a reduction in sperm count and motility.

The effect is latent because the "faulty batches" from heat exposure with fewer total and motile sperm are only apparent in test after being stored for a couple weeks in the epididymis.Image
Read 5 tweets
Aug 28
5 things you can do to combat phone addiction 🧵

1. Set ALL NOTIFICATIONS OFF as your default

It takes 23 mins on avg to regain focus after being distracted by your phone. Only allow text notifications from people who contact you in an emergency.Image
If you do need notifications, be strategic about which ones you allow: Image
2. Resist the urge to check Instagram and TikTok

Apps like One Sec or Opal let you add loading screens before accessing addictive apps.

They can force you to look at yourself in the camera for a few seconds, or make you spin your phone around 4 times before granting access.

If that doesn’t work:
The app Brick comes with a physical “brick” to lock or unlock groups of apps on your phone.
+ Put the brick on your fridge
+ Tap your phone against it to block all non-work apps
+ Go to the kitchen to unlock if you need to check something or spend 15 mins on social media

You can also give someone else the Brick to keep you accountable.Image
Read 6 tweets

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