Mike Hoerger, PhD MSCR MBA Profile picture
Dec 25 8 tweets 5 min read Read on X
1/
PMC COVID-19 Tracker, Dec 25, 2023 (U.S.)

At peak surge, we will have 2 million U.S. #COVID infections/day.

Nearly 1 in 3 Americans will get infected during the peak 2 months of this winter surge. That’s 105 million infections & >5 million resulting #LongCOVID cases.U.S. Winter 2023-24 COVID Surge				 	Best Estimate		Range	 Rank among COVID waves	2nd		2nd	4th Date of peak	Jan 10		Jan 3	Jan 17 Daily infections at peak	2.0 million/day		1.7 million/day	2.1 million/day Percentage of population infectious at peak	4.1% (1 in 24)		3.7% (1 in 27)	4.4% (1 in 23)  CURRENT ESTIMATES FOR December 25, 2023 Wastewater Levels (copies/mL) 1137 New Daily Cases 1,655,000 % of Population Infectious 3.46% (1 in 29 people) New Daily Long COVID Cases  83,000 to 331,000  4-WEEK FORECAST FOR January 22, 2024 Wastewater Levels (copies/mL) 1,293 (14% higher) New Daily Cases 1,8...
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Today on Christmas, 3.5% of the U.S. population (1 in 29) is actively infectious with #COVID & rising toward a Jan 10 peak.

COVID transmission is higher than during 94.7% of the pandemic. There's a 50% chance of a COVID exposure if interacting with 20 people today. There is more COVID-19 transmission today        than during 94.7% of the pandemic.  Number of People  |  Chances Anyone is Infectious	 1	3.5% 2	6.8% 3	10.0% 4	13.2% 5	16.2% 6	19.1% 7	21.9% 8	24.6% 9	27.2% 10	29.7% 15	41.1% 20	50.6% 25	58.6% 30	65.3% 35	70.9% 40	75.6% 50	82.8% 75	92.9% 100	97.1% 150	99.5% 200	99.9% 300	>99.9% 400	>99.9% 500	>99.9%
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We posted our first “Christmas Risk” table on October 30, and as you can see, it performed exceedingly well.

These tables should lend confidence in the PMC dashboard, and raise concern about public health leadership and the news media.

Being able to accurately predict within a few percentage points the probability of infectiousness in a room of 20 people, for example, 8 weeks out is very helpful for planning. Moreover, many would estimate *today* that the risk in a room of 20 people is <1 percentage point. We’re talking about potentially magnitudes of difference in risk estimation, and this was highly predictable long ago. It’s not something unanticipated due to a new oddly-behaving sub-variant (there will always be a new sub-variant this time of year when no mitigation) or high rates of air travel (also unsurprising). It was highly predictable, and public health officials should not be given an out. The media will try to frame this as an unanticipated surge, and it simply was not, according to those who know how to forecast.

The formal PMC forecast keeps to 4 weeks, but sometimes a more speculative long-term estimate can help with planning, especially surrounding booking travel plans. People might want to take a wait-and-see approach to booking, purchase travel insurance, or cancel entirely. We characterized the table with appropriate caution, and hopefully it was helpful.

Putting out these forecasts requires putting one’s professional reputation as a scientist on the line. It’s very easy for anonymous and fake-name accounts to make speculative forecasts. The information we provide tends to be highly conservative within a much broader set of analyses, sensitivity analyses, and scenarios considered. Know that we are very cautious about what information we share, post considerable detail on the underlying methodology and assumptions in the online report, and carefully describe how estimates may be more precise or more speculative at times. A published peer-reviewed article will ultimately account for the strengths and limitations in the accuracy of the model.Comparison of the "Christmas Risk" table posted on October 30th versus today. The 8-week predictions were highly accurate. In October, we predicted that interacting with 20 people on Christmas Day would lead to a 47% chance of exposure. Today, we estimate that same risk as 50.6%, a negligible difference and vastly at odds with public expectations concerning risk.
4/
Christmas infections will seed New Year’s Eve/Day infections, leading to a peak around the 10th.

Around New Year’s, interacting with 15-20 people means a 50% chance of a COVID exposure. In a restaurant or plane, the risk jumps to >98%. Number of People  |  Chances Anyone is Infectious	 1	3.9% 2	7.6% 3	11.2% 4	14.6% 5	17.9% 6	21.1% 7	24.1% 8	27.1% 9	29.9% 10	32.6% 15	44.7% 20	54.6% 25	62.7% 30	69.4% 35	74.9% 40	79.4% 50	86.1% 75	94.8% 100	98.1% 150	99.7% 200	>99.9% 300	>99.9% 400	>99.9% 500	>99.9%
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Zooming out to the full pandemic, we are in the 8th U.S. COVID wave & 2nd biggest all-time.

That assumes no major wastewater corrections.

We've surpassed the 1st wave, winter of 2020-21, Delta, & 2023 summer wave. Claims that “COVID is over” are harmful misinformation. There is more COVID-19 transmission today        than during 94.7% of the pandemic.  CURRENT ESTIMATES FOR December 25, 2023 Wastewater Levels (copies/mL) 1137 New Daily Cases 1,655,000 % of Population Infectious 3.46% (1 in 29 people) New Daily Long COVID Cases 83,000 to 331,000  WEEKLY ESTIMATES FOR December 25, 2023 New Weekly Cases 11,600,000 New Weekly Long COVID Cases 579,000 to 2,317,000  2023 CUMULATIVE ESTIMATES AS OF December 25, 2023 Total 2023 Cases To Date 241,674,380 Total 2023 Long COVID Cases To Date 12,084,000 to 48,335,000
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Hospitals & clinicians should require universal masking. Public health officials should warn of the surge & recommend multi-layered mitigation.

Anything less is grounded in politics, short-term revenue, or defensiveness against COVID anxiety.
7/
Here's the full PMC Dashboard for Dec 25 to Jan 22.

You can read the full report here:

Thank you for your continued questions, suggestions, gratitude, infographics, videos, & sharing across other platforms. pmc19.com/data/
There is more COVID-19 transmission today	        than during 94.7% of the pandemic.	 	 CURRENT ESTIMATES FOR	 December 25, 2023	 Wastewater Levels (copies/mL)	 1137	 New Daily Cases	 1,655,000	 % of Population Infectious	 3.46% (1 in 29 people)	 New Daily Long COVID Cases	 83,000 to 331,000	 	 WEEKLY ESTIMATES FOR	 December 25, 2023	 New Weekly Cases	 11,600,000	 New Weekly Long COVID Cases	 579,000 to 2,317,000	 	 2023 CUMULATIVE ESTIMATES AS OF	 December 25, 2023	 Total 2023 Cases To Date	 241,674,380	 Total 2023 Long COVID Cases To Date	 12,084,000 to 48,335,000	 	 4-WEEK FORECAST FOR	 ...
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If you're using the PMC dashboard to help others, please post your success stories, infographics, photos, videos, and more in the following Tweet.

We will make awards at the end of the year. The examples are inspirational.

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More from @michael_hoerger

Dec 26
Someone has purchased a low-quality high-volume anti-#COVID-awareness bot farm. I've had to block 500 people the past few days. I appreciate good humor, but these bots are sub-pun-level basic, not even any fun.

These are my Top 7 tips for dealing with #bots & #trolls.
🧵Troll eyes within COVID images
Bot Tip #1: In settings, shut off direct messaging from people you don't follow.

Bye-bye #bots & #trolls.Shows how to shut off non-follower DMs in settings
Bot Tip #2: In settings, shut off notifications from people who don't follow you.

This will reduce #bot & #troll notifications.

Consider other options. I prefer this over blocking notifications from people I don't follow because it could be have new follower.Settings: Mute notifications from people who don't follow you.
Read 10 tweets
Dec 24
As COVID transmission spikes, you may have opportunities to raise awareness about #LongCOVID.

These are a few of the the most popular videos I've shared that people found useful. A family member or friend might find one of them relatable too.

Video Thread 📽️🧵 Screenshots of four #LongCovid videos provided in the thread
2/
"I hope to god I'm wrong. I've never wanted to be more wrong in my life.... Worst case scenario... we are going to see a tsunami of cardiovascular disease over the next few decades." #LongCovid

The whole talk is well worth listening to.
3/
With #PublicHealth very weak at the moment, these examples of families dealing with #LongCOVID will become the norm.

Incidentally, my kids enjoy the product.

Read 5 tweets
Dec 20
As a clinical health psychologist, I notice that many people are using psychological defense mechanisms to downplay the risk of COVID.

These are my Top 7 examples:

🧵 Top 7 Psychological Defense Mechanisms Used to Downplay COVID
#1 – Denial – Pretending a problem does not exist to provide artificial relief from anxiety.

Examples:

“During COVID” or “During the pandemic” (past tense)

“The pandemic is over”

“Covid is mild”

“It’s gotten milder”

“Covid is now like a cold or the flu”

“Masks don’t work anyway”

“Covid is NOT airborne”

“Pandemic of the unvaccinated”

“Schools are safe”

“Children don’t transmit COVID”

“Covid is mild in young people”

“Summer flu”

“I’m sick but it’s not Covid”

Taking a rapid test only once

Using self-reported case estimates (25x underestimate) rather than wastewater-derived case estimation

Using hospitalization capacity estimates to enact public health precautions (lagging indicator)

Citing mortality estimates rather than excess mortality estimates. Citing excess mortality without adjusting for survivorship bias.This is from a psychology book by Nancy McWilliams. I will post a link to a PDF of newer edition of the full book at the end of the thread. If someone has a better "ALT" trick, please educate me on this one.
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#2 – Projection – When someone takes what they are feeling and attempts to put it on someone else to artificially reduce their own anxiety.

Examples:

“Stop living in fear.” (the attacker is living in fear)

“You can take your mask off.” (they are insecure about being unmasked themselves)

“When are you going to stop masking?”

“You can’t live in fear forever.”This is from a psychology book by Nancy McWilliams. I will post a link to a PDF of newer edition of the full book at the end of the thread. If someone has a better "ALT" trick, please educate me on this one.
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Read 9 tweets
Dec 18
1/
PMC COVID-19 Tracker, Dec 18, 2023

We are headed into potentially the 2nd largest COVID surge all-time in the U.S.

If #wastewater levels follow historic trends, we will reach 2 million infections/day at peak surge with 4.2% of the population actively infectious on Jan 10.U.S. Winter 2023-24 COVID Surge				 	Best Estimate		Range	  Rank among COVID waves	2nd		2nd	4th  Date of peak	Jan 10		Jan 3	Jan 17  Daily infections at peak	2.0 million/day		1.7 million/day	2.2 million/day  Percentage of population infectious at peak	4.2% (1 in 24)		3.7% (1 in 27)	4.6% (1 in 22)
2/
The winter peak should arrive between Jan 3 and Jan 17. The model estimates a peak of 1.7 to 2.2 million infections per day.

If unlucky, 1 in 20 people will be infectious, and it will be the 2nd largest wave. If lucky, more like 1 in 30, and the 4th largest wave.

Consider optimistic and pessimistic scenarios not captured by these models.

Optimism:
A rosy scenario would be that the peak occurs a week earlier at a slightly lower level (1.6-1.7 infections/day like last winter or the preceding summer). The level of acceleration in transmission argues against that, in favor of a higher peak, but Biobot is reporting some unusual regional variation (much lower transmission in the U.S. South and West). Moreover, historical patterns of how transmission should or should not accelerate cannot account for existing variation on population-level immunity due to variation in prior exposure history, recency of vaccination, and how well the current vaccine matches disseminating subvariants relative to prior vaccines. Finally, Biobot wastewater sites could be overreporting, and levels could get corrected downward. Each of these factors is highly plausible, but the “rosy” scenario remains quite bleak and suggests the pandemic remains far from “over.”

Pessimism:
Also, consider more pessimistic scenarios. Current vaccination rates remain extremely low, and several other countries are reporting atypically high acceleration via wastewater data. Placing plausible hypothetical values in the model, it is difficult to imagine a scenario where the U.S. reaches 2.5 million infections/day. Sometimes, people draw graphs showing a continued acceleration like BA.1, but such models seem to reflect imagination rather than data. The data do not suggest an evidence for a BA.1-level surge.U.S. Winter 2023-24 COVID Surge				 	Best Estimate		Range	  Rank among COVID waves	2nd		2nd	4th  Date of peak	Jan 10		Jan 3	Jan 17  Daily infections at peak	2.0 million/day		1.7 million/day	2.2 million/day  Percentage of population infectious at peak	4.2% (1 in 24)		3.7% (1 in 27)	4.6% (1 in 22)
3/
COVID transmission is already very bad in the U.S. and getting worse.

Today:
🔹1.4 million daily infections
🔹1 in 35 infectious (2.9%)

In 4 weeks (Jan 15):
🔹1.9 million daily infections
🔹1 in 24 infectious (4.2%) CURRENT ESTIMATES FOR December 18, 2023 Wastewater Levels (copies/mL) 950 New Daily Cases 1,382,000 % of Population Infectious 2.89% (1 in 35 people) New Daily Long COVID Cases  69,000 to 276,000   4-WEEK FORECAST FOR January 15, 2024 Wastewater Levels (copies/mL) 1,363 (44% higher) New Daily Cases 1,984,000 % of Population Infectious 4.15% (1 in 24 people) New Daily Long COVID Cases  99,000 to 397,000
Read 11 tweets
Dec 11
PMC COVID-19 Tracker, Dec 11, 2023
The surge continues.

Today:
🔹1.2 million daily infections
🔹1 in 41 infectious (2.5%)

In 4 weeks (Jan 8):
🔹1.6 million daily infections
🔹1 in 30 infectious (3.3%)

1/

A few key methodologic updates.
1) Biobot correct levels downward for the past two weeks, so you might notice that this week's estimates seem similar to last week's or marginally lower.

2) Our forecasting model uses a combination of historic data (situation past several years) and current data (past 4 weeks). In the historic model, we switched from using mean-type data to median-type data. This avoids overestimating levels based on the BA.1 surge and allows us to predict accurately a little faster, rather than predicting high and waiting for the current 4-week's data to correct it.

3) The forecasts depend a lot on the most recent week's data. To the extent Biobot is accurate or inaccurate in real-time, this leads to divergent forecasts.CURRENT ESTIMATES FOR December 11, 2023 Wastewater Levels (copies/mL) 807 New Daily Cases 1,174,000 % of Population Infectious 2.46% (1 in 41 people) New Daily Long COVID Cases  59,000 to 235,000   4-WEEK FORECAST FOR January 8, 2024 Wastewater Levels (copies/mL) 1,083 (34% higher) New Daily Cases 1,576,000 % of Population Infectious 3.3% (1 in 30 people) New Daily Long COVID Cases  79,000 to 315,000
You'll see the forecasts differ considerably (1.3 to 1.9 million daily infections) in 4 weeks.

2/

However, they mostly agree on the peak. It could be as early as Jan 1 or as late as Jan 15. It's a moot point. Transmission will be similar across that timespan and the weekly reports lack the precision to say whether it will peak on the 4th or 9th, for example. Early Jan will remain bad.

Details:

The real-time model (purple) anticipates the highest surge levels. This assumes that Biobot real-time reports are accurate, but they were substantially corrected for the past two weeks, and there were some issues with real-time accuracy during the summer wave. The turtle model (green) discount’s the most recent week’s data as an aberration, assumes transmission should be corrected upward a little, and predicts a steady rise with peak around January 1. The cheetah model (yellow) says that because last week’s data were corrected downward, this week’s estimate should be too, so it’s much more conservative on the next several weeks. The average of all models (red) guides forecasted numbers for the next four weeks. A month from now, we will see about 1.6 million new U.S. cases per day (range of 1.3 to 1.9 million across forecasting models), with 3.3% of the U.S. population or 1 in 30 people actively infectious.Zoomed in version of prior tweet
Zooming out, you'll see that we're in a very bad place historically. With the divergent forecasts, it's merely a matter of whether this is the 2nd biggest U.S. COVID surge or 4th biggest.

The #LongCOVID cases resulting from these infections may top 400,000/week.

3/ There is more COVID-19 transmission today        than during 87.2% of the pandemic.  CURRENT ESTIMATES FOR December 11, 2023 Wastewater Levels (copies/mL) 807 New Daily Cases 1,174,000 % of Population Infectious 2.46% (1 in 41 people) New Daily Long COVID Cases 59,000 to 235,000  WEEKLY ESTIMATES FOR December 11, 2023 New Weekly Cases 8,200,000 New Weekly Long COVID Cases 411,000 to 1,644,000  2023 CUMULATIVE ESTIMATES AS OF December 11, 2023 Total 2023 Cases To Date 221,642,490 Total 2023 Long COVID Cases To Date 11,082,000 to 44,328,000
Read 8 tweets
Dec 11
There's a lot of dichotomous thinking about #COVID risk on #airplanes.

Some believe it's completely safe, others completable dangerous.

I minimize flight travel and wouldn't fly without a fit-tested high-quality mask (N95 or elastomeric respirator). Here's why. 🧵

1/16 "COVID-19, Unsafe As We Breathe: The designed-in dangers of the American Airplane, By Dr. Hoerger"  A play on words of the book, "Unsafe at any speed: The designed-in dangers of the American automobile" (1965) by Ralph Nader
Field research from @sri_srikrishna found that across 3 models of aircrafts, they had an air cleaning rate of 10.9-11.8 air changes per hour (ACH).

A U.S. operating room should have 15 ACH, so flights are pretty good, right?

Wrong. I'll explain why.
2/16 Figures showing an average of 11.7 ACH on three flights, from Devabhaktuni Srikrishna's pre-print, "What ACH is equivalent to a passenger airplane inflight for protection from SARS-Cov-2 and other aerosol contaminants?"
10-12 air changes per hour (ACH) on a flight sounds good, even overkill, right?

Actually, no.

If the air has good mixing, the best case scenario is that each air change is still imperfectly efficient, cleaning out about 2/3 of the air each air change.

Uh oh.
3/16
Read 16 tweets

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