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Emmanuel Profile picture
@ejustin46
Jan 22 • 9 tweets • 3 min read • Read on X
Scrolly
UNEXPLAINED POST-ACUTE INFECTION SYNDROMES
A very interesting study of Akiko Kawasaki @VirusesImmunity

WHICH INFECTIONS ? Image
2) WHICH SYMPTOMS ? Image
3) WHICH SYMPTOMS by infection Image
4) HOW LONG ? Image
5) WHY ?
1st hypothesis : Pathogens reservoirs or remnants Image
6) WHY ?
2nd hypothesis: Dysbiosis/reactivation Image
7) WHY ?
3rd hypothesis : Autoimmunity Image
8) WHY ?
4th hypothesis : Tissue damage Image
9) SOURCE :


Thanks for reading 🙏nature.com/articles/s4159…

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More from @ejustin46

Emmanuel Profile picture
Jan 23
COVID-19. The KEY ROLE of MYELOID CELLS
(mega-thread)

Myeloid cells are a type of white blood cell that includes neutrophils, monocytes, and macrophages.
During a SARS-CoV-2 infection, Image
2) ...myeloid cells are activated and recruited to the site of infection. They release various pro-inflammatory molecules, such as cytokines and chemokines, to attract other immune cells and enhance the immune response. Image
3) "The immune response is activated in ASYMPTOMATIC infection, but is dysregulated in mild and severe COVID-19 patients. Our data suggest that the turning point depends on the function of MYELOID cells and neutrophils."
ncbi.nlm.nih.gov/pmc/articles/P…
Image
Read 9 tweets
Emmanuel Profile picture
Jan 23
SARS-COV-2 INFECTS your HEART, BRAIN and OTHER ORGANS

(mega-thread COVID & ORGANS) Image
2) "Organ Involvement in COVID-19: A Molecular Investigation of Autopsied Patients"
mdpi.com/2076-2607/10/7…
Image
3) "SARS-CoV-2 Systemic Effects: New Clues"
mdpi.com/2076-2607/11/5…
Image
Read 10 tweets
Emmanuel Profile picture
Jan 21
When "Mr SARS-COV-2" 🤢 meets "Mrs INFLUENZA" 🥶 (2nd part)

7) In this 4th study, researchers showed that "sequential coinfection with A(H1N1)pdm09 one day prior to SARS-CoV-2 exposure resulted in a lower lung SARS-CoV-2 titer ... Image
8) ...and viral load than with SARS-CoV-2 monoinfection, but a higher lung A(H1N1)pdm09 viral load." Image
9) "Coinfection also increased intestinal inflammation with more SARS-CoV-2 nucleoprotein expression in enterocytes." Image
Read 7 tweets
Emmanuel Profile picture
Jan 21
When "Mr SARS-COV-2" 🤢 meets "Mrs INFLUENZA" 🥶 (1st part)

This is a fascinating subject because we sometimes see, COVID-19 which seems blocking the progression of respiratory diseases, or sometimes giving the impression of contributing to their development. What about it? Image
2) In a first study, Japanese researchers investigated the impact of COVID-19 on influenza activity.
They compared the number of cases positive for COVID-19 and for influenza across 22 representative countries.
onlinelibrary.wiley.com/doi/10.1111/ir…
Image
3) Theirs results demonstrate alternating prevalence of SARS-CoV-2 and influenza virus. Image
Read 6 tweets
Emmanuel Profile picture
Jan 21
COVID-19 MAKES your LIFE MISERABLE !

A new study showed how : "SARS-CoV-2 infection causes DOPAMINERGIC NEURON SENESCENCE"
... hijacking your "happy" hormones Image
2) The study
cell.com/cell-stem-cell…
Image
3) SARS-COV-2 induces senescence of DA neurons Image
Read 5 tweets
Emmanuel Profile picture
Jan 21
LONG COVID
(Recent articles in Nature not paywall)

1. "Long-COVID signatures identified in huge analysis of blood proteins"
H/t @GourlaySyd
nature.com/articles/d4158…
Image
2) "Long COVID research risks losing momentum – we need a moonshot"
nature.com/articles/d4158…
Image
3) "Long COVID is a double curse in low-income nations — here’s why"
nature.com/articles/d4158…
Image
Read 4 tweets

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