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Emmanuel Profile picture
@ejustin46
Jan 23, 2024 • 10 tweets • 4 min read • Read on X
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SARS-COV-2 INFECTS your HEART, BRAIN and OTHER ORGANS

(mega-thread COVID & ORGANS) Image
2) "Organ Involvement in COVID-19: A Molecular Investigation of Autopsied Patients"
mdpi.com/2076-2607/10/7…
Image
3) "SARS-CoV-2 Systemic Effects: New Clues"
mdpi.com/2076-2607/11/5…
Image
4) "Molecular Structure, Pathophysiology, and Diagnosis of COVID-19"
researchgate.net/publication/34…
Image
5)" Extrapulmonary manifestations of COVID-19" nature.com/articles/s4159…
Image
6) "One disease, many faces-typical and atypical presentations of SARS-CoV-2 infection-related COVID-19 disease"
wjgnet.com/2307-8960/full…
Image
7) "Systemic and organ-specific immune-related manifestations of COVID-19"
nature.com/articles/s4158…
Image
8) "From Cell to Symptoms: The Role of SARS-CoV-2 Cytopathic Effects in the Pathogenesis of COVID-19 and Long COVID"
mdpi.com/1422-0067/24/9…
Image
9) Infographic: Bodily Systems Affected by Long COVID
the-scientist.com/infographics/i…
Image
10) Thanks for reading 🙏

(Illustration: V. ALTOUNIAN/SCIENCE) Image

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More from @ejustin46

Emmanuel Profile picture
Apr 24
From Lung Damage to Gut Dysbiosis:
The Lasting Implications of SARS-CoV-2 Variant-Specific Microbiome Changes (From Wuhan strain to Omicron)
labanimres.biomedcentral.com/articles/10.11…Image
2) The Wuhan strain of SARS-CoV-2 caused serious damage to the lungs of infected mice. The mice had a very high chance of dying from this strain. The researchers also looked at the bacteria in the lungs and guts of the infected mice. Image
3) The Wuhan strain increased harmful bacteria like E. coli in the lungs. This can make the lungs more prone to other infections.

The Omicron variant caused different changes in the gut bacteria of the mice. It increased certain bacteria linked to inflammation in the gut. Image
Read 5 tweets
Emmanuel Profile picture
Apr 23
What are GAMMA CORONAVIRUSES ?
And why did we decide to talk about it? Image
Image
2) A brief reminder :

▶️ SARS-CoV-2 belongs to the family Coronaviridae, is classified as a coronavirus and is responsible for COVID-19
▶️ Bird Flu refers to various strains of the influenza virus, particularly those in the Orthomyxoviridae family including H5N1 and H7N9. Image
3) ▶️ Gammacoronavirus belongs to the family Coronaviridae like SARS-COV-2.

Some notable gammacoronaviruses include:
- Infectious Bronchitis Virus (IBV): A major pathogen in poultry responsible for respiratory disease and reduced egg production. Image
Read 10 tweets
Emmanuel Profile picture
Apr 21
A TREATMENT that Could Finally END Long COVID Suffering ?

This isn't the first time a treatment has been announced, and as millions continue to struggle with long Covid, we need to remain both cautious and hopeful 🤗 Image
2) Researchers at WEHI announced that they discovered a new drug that can stop long COVID symptoms in mice. This drug is more effective than the current top treatment, Paxlovid, for both long COVID and acute COVID cases. Image
3) They focused on a specific protein called PLpro that other treatments haven't targeted well. This breakthrough could lead to new medicines for long COVID, a condition where people continue to feel sick long after their COVID-19 infection. Image
Read 4 tweets
Emmanuel Profile picture
Apr 21
Experts Provide (finally !) Roadmap to Address the Complexities of Long COVID

... with top experts👍as @AndrewEwing11 @DavidJoffe64 and the Long COVID consensus expert panel 💥💯
ann-clinmicrob.biomedcentral.com/articles/10.11…Image
2) Long COVID is a complex condition that affects many people after they have had COVID-19. It can cause a wide range of symptoms that last for a long time. There are not many clear guidelines on how to diagnose and treat Long COVID. Image
3) An international group of 179 experts from 28 countries worked together to provide recommendations on Long COVID. They used a survey method called the Delphi process to reach consensus on important issues. Image
Read 8 tweets
Emmanuel Profile picture
Apr 20
We're not about to feel bad for SARS-CoV-2 infecting us humans. But let's be real - the life of a virus isn't exactly a walk in the park 🥴
These little buggers are constantly trying to "have their cake and eat it too."

(An astonishing study 👇💥💯) virologyj.biomedcentral.com/articles/10.11…Image
2) On one hand, they need to spread like wildfire from person to person. But on the other hand, they also have to make tons of copies of themselves inside each infected host.

Not an easy balance to strike, is it? Image
3) Kinda like trying to plan the perfect birthday party - you want all your friends to come, but you also want to make sure there's enough cake for everyone. Image
Read 6 tweets
Emmanuel Profile picture
Apr 20
WHY is it IMPOSSIBLE to COMPLETELY ELIMINATE the SARS-CoV-2 virus? (Final part)

What if my question concerning viral persistence was not asked properly? Image
2) Let me try to explain in simple words.

Viral persistence refers to the ability of some viruses to stay in the body for a long time, often even after the initial infection has cleared. This means that the virus can remain in certain tissues or cells and ... Image
3) ... may not cause noticeable symptoms. Some common examples of viruses that can persist in the body are:

▶️ **HIV**: This virus can remain in the body for years, hiding in immune cells. Even with treatment, it can stay dormant and may reactivate later. Image
Read 10 tweets

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