THE CONFUSION between a R0 at 18 for MEASLES and an R0 at 2,5 for WUHAN or at 5, 10, even 20 (in a recent study) for OMICRONS
2) The basic reproduction number R0 is when one person develops an infection and passes it to 1, 2, 10 or 18 persons. It is relevant in a population with no immunity as for example, people not vaccinated against measles.
3) When widespread immunity starts to develop, we will use the Re effective reproduction number or Rt.
Re is the number of people in a population who can be infected by an individual at any specific time. It changes as the population becomes more or less immunized.
3) If the R0 of Wuhan strain was estimated a 2.5, with the increasing immune escape of Omicrons, it is increased to nearly 8.
4) In a recent study, they even estimated the R0 of Omicron at 20.
5) But, once again, due to the level of immunity of a part of the population, what is interesting for COVID-19, is the Re which depends in a country on the average level of immunity of the population.
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What Are the KEY DIFFERENCES That Make SARS-CoV-2 UNIQUE Among RESPIRATORY VIRUSES Like INFLUENZA and RHINOVIRUSES?
▶️ TRANSMISSION MECHANISM :
- **SARS-CoV-2** primarily spreads through aerosols and contact with contaminated surfaces. It has a longer viral shedding period ...
2) ...which can lead to asymptomatic spread.
- **Influenza**: Also spreads via respiratory droplets, but typically has a shorter contagious period and less asymptomatic transmission compared to SARS-CoV-2.
3) - **Rhinoviruses**: Mainly spread through direct contact and respiratory droplets but are often more localized to the upper respiratory tract.
▶️ INFECTIOUS DOSE:
- **SARS-CoV-2**: Can be infectious with a lower viral load, which may contribute to its rapid spread.
SPERM, STRESS, and the NEXT GENERATION:
The Long-Term Anxious Legacy of COVID-19 and potential impact on Millions of Kids
A recent study in Nature reveals that mice infected with SARS-CoV-2 exhibited changes in their sperm that led to increased anxiety levels in their offspring
2) We had already warned several times about the risks of COVID-19 on sperm.
IS SARS-CoV-2 BECOMING "INVISIBLE"? The Hidden Truth Behind the Pandemic
As the world strives to move past the COVID-19 pandemic, a troubling narrative has emerged: the perception that SARS-CoV-2 is becoming "invisible."
2) Governments and communities are eager to return to normalcy, leading to a tendency to downplay the virus's severity. Reports of new infections and long COVID cases have been totally minimized, creating a false sense of security ...
3) ...that the virus is no longer a significant threat. However, this perception is not only a matter of public sentiment. The virus itself has evolved, most notably with the emergence of the Omicron variant. Recent research reveals that Omicron exhibits a remarkable ability ...
2) This research shows that SARS-CoV-2, the virus that causes COVID-19, stops infected cells from dying. Normally, when cells die, it helps stop viruses from spreading. By keeping these cells alive longer, SARS-CoV-2 allows itself to multiply and also helps other viruses ...
3) ... like influenza A, grow more easily.
When someone has both SARS-CoV-2 and influenza A, the two viruses can make a person much sicker. The immune system gets overwhelmed, leading to more inflammation and damage to the lungs.
ENTROPY UNLEASHED:
How Viral Protein Interactions Drive Coronavirus Adaptation in Bats and Humans
Entropy, in a general sense, refers to the level of disorder or randomness in a system. biorxiv.org/content/10.110…
2) When we talk about protein interactions and viral behavior, entropy can be viewed as a measure of how complex and varied these interactions are.
In the context of the study about coronavirus interactions in bat and human cells, here's a simplified breakdown.
3) **Complex Interactions**: The study identifies how proteins from the coronavirus interact with host cells (both bats and humans). These interactions can be highly ordered (low entropy) or more chaotic (high entropy).