Thread by @vipintukur

A new research underscores how much more we have to learn about what SAR-CoV-2 virus can do to our children, particularly to their brains. The study collected brain scan data from nearly 2 years’ worth of scientific literature to try to summarize what we know so far. 1/

The systematic review & meta analysis of 96 studies finds that a substantial proportion of pediatric COVID-19 patients with neurological symptoms exhibit abnormal neuroimaging findings, with 43.74% of children in the included studies demonstrating such abnormalities. 2/

The researchers identified different neurological signs in the children whose brains were scanned. They include neurovascular findings (8.22%), ADEM-like lesions (7.69%), encephalitic pattern (13.95%), myelitis (4.60%), transient splenial lesions (16.26%) & other 3/

The observed incidence of neurological abnormalities in pediatric COVID-19 patients raises several important clinical and research implications.

First, it highlights the necessity for a high index of suspicion for neurological complications in children with COVID-19. 4/

Second, the findings of this study emphasize the importance of continued research into the long-term consequences of COVID-19 in children. 5/5

nature.com/articles/s4159…