Thread by @Outdoctrination

Over the years, these tools have helped me and those I have worked with REVERSE digestive issues.

16 SUPPLEMENTS TO HELP HEAL YOUR GUT (and how to use them):

1. VITAMIN D:

⬨ Preserves gut mucus
⬨ Critical for gut immune function
⬨ Antimicrobial
⬨ Antibiofilm
⬨ Anti-stress (lowers cortisol)
⬨ Direct anti-serotonin
⬨ Anti-inflammatory
⬨ Reduces IBS symptoms

VITAMIN D DOSING:

Ideally you get labwork done, >40 ng/mL is where I like to see this.

5,000 to 10,000 IU daily is a good range.

Yes, you can get it from sun, but oral vitamin D is noticeably beneficial in my experience.

This is the product I use.

healthnatura.com/vitamin-d3-in-…

2. LACTOFERRIN

⬨ Repairs gut barrier
⬨ Decreases gut inflammation
⬨ Bolsters iron absorption (unabsorbed iron is a serious problem for the gut)
⬨ Binds endotoxin
⬨ Antibacterial
⬨ Antiparasitic
⬨ Anti-diarrheal
⬨ Anti-nausea
⬨ Reduces abdominal pain

LACTOFERRIN DOSING: Doses range anywhere from 100 mg to 3 grams

I would probably start on the low end and gradually move up depending on response.

This is the best one I have used.

lifegivingstore.com/store/grass-fe…

3. LYSINE: a natural serotonin antagonist

Serotonin is a primary mediator of all gut problems.

Lysine:

⬨ Helps repair gut barrier
⬨ Anti-anxiety
⬨ Reduces diarrhea
⬨ Reduces “gut stress”
⬨ Reduces gut sensitivity

LYSINE DOSING: Lysine HCl at anywhere from 1 to 15 grams daily seems to be the ideal range.

This is the product I use.

purebulk.com/products/magne…

4. VITAMIN K2

⬨ Antibacterial
⬨ Anti-inflammatory
⬨ Key for intestinal cell function

One of my personal favorites.

I use anywhere from 20-40 mg, which is a massive dose (but very safe), and have had success with clients in this range:

healthnatura.com/true-k2-mk4-1-…

5. GLUTAMINE

⬨ Main small intestinal metabolic substrate
⬨ Key immune system metabolic substrate
⬨ Prevents gut bacterial infections
⬨ Anti inflammatory
⬨ Critical for intestinal barrier
⬨ Improves abdominal pain
⬨ Reduces bloating
⬨ Improves bowel movements

DOSING GLUTAMINE:

5g 3x a day 8 weeks has been used successfully

I would highly recommend doing at least that long as shorter term use does not seem to be as beneficial

This is the glutamine I use: purebulk.com/products/l-glu…

6. MASTIC GUM

⬨ Anti inflammatory (even against Crohn’s)
⬨ Pro-Motility
⬨ Antibacterial / antifungal
⬨ Increases saliva
⬨ Increases appetite
⬨ Reduces bloating

Of course, we love @GrecoGum.

I think you can realistically chew as much as you want, but at least 30-45 minutes of chewing seems to be where the magic happens.

grecogum.com/?rfsn=7547359.…

7. ACTIVATED CHARCOAL

⬨ Prevents estrogen reabsorption
⬨ Antibacterial
⬨ Anti endotoxin
⬨ Repair intestinal lining
⬨ Reduces gas
⬨ Reduces bloating
⬨ Reduces diarrhea

500 mg to 10 grams daily

The brand I use:

amazon.com/Bulletproof-Ch…

8. HERBAL ANTIMICROBIALS

Specifically:

Dysbiocide + FC Cidal

OR

Candibactin-AR + Candibactin-BR

These are the only herbals I am aware of that have been tested in a human trial for gut issues, and they worked at least as well as the leading antibiotic.

The doses used in the study were 2 capsules twice daily of either Dysbiocide + FC Cidal or Candibactin-AR + Candibactin-BR

Easy to overdo antimicrobials.

Start low, see how you tolerate. Often, less is more. You can always increase later.

Dysbiocide:
FC Cidal:
Candibactin AR:
Candibactin BR: shop.bioticsresearch.com/products/dysbi…
shop.bioticsresearch.com/products/fc-ci…
metagenics.com/candibactin-ar
metagenics.com/candibactin-br

9. Triple therapy probiotics

⬨ Helps digest milk and plant carvs
⬨ Supports proper gut pH
⬨ Produces antimicrobials
⬨ Prevent pathogen overgrowth
⬨ Maintain intestinal metabolism, immunity
⬨ Help maintain gut barrier

Dosing:

10-15 billion CFU/day Lacto/Bifido blend
~10 billion CFU/day spore forming/soil based
~5-10 billion CFU/day S Boulardii

Multi strain works better, longer duration is key, it may take multiple months for effect.

Fantastic product:

store.drruscio.com/products/tripl…

10. NATURAL DESICCATED THYROID

⬨ Key for gut regeneration, healing
⬨ Pro-motility
⬨ Increases digestive enzymes, stomach acid
⬨ Critical for gut immunity, gut barrier

A lack of thyroid hormone can commonly result in
⬨ Nausea
⬨ Constipation
⬨ Diarrhea
⬨ Bacterial overgrowth

DOSING NATURAL DESICCATED THYROID:

https://twitter.com/Outdoctrination/status/1740775975275618759

By far my favorite natural desiccated thyroid product:
lifegivingstore.com/grass-fed-beef…

11. CASCARA SAGRADA:

⬨ Pro motility (laxative)
⬨ Anti inflammatory

This is the one I prefer.

I would start out with very small doses, maybe a pinch and do more if no effect is felt.

Do NOT just slam a bunch, you will have a bad time.

lifegivingstore.com/store/cascara-…

12. MAGNESIUM

⬨ Depleted in inflammatory bowel disease
⬨ Prevents dry stools
⬨ Anti-nausea
⬨ Anti-constipation

I prefer magnesium glycinate.

I would start off with maybe 200 mg of magnesium glycinate and work your way up.

Too much, you will get loose stools.

Splitting up doses can make this less likely.

Personally, I do 700 mg once a day.

purebulk.com/products/magne…

13. VITAMIN A:

⬨ Indispensable for gut immune function (food tolerance, reducing bacteria)
⬨ Direct anti-serotonin
⬨ Prevents gut inflammation
⬨ Preserves mitochondrial function

I think the lower dose of 2,500 IU is a good starting point, but I’ve heard success with 10-15,000 IU.

This is the best product I am aware of:

healthnatura.com/simply-a-2-500…

14. BUTYRATE

⬨ Fuel for colon cells
⬨ Decreases colon oxygen leak→prevents pathogen growth
⬨ Decreases colonic pH → antimicrobial
⬨ Anti inflammatory
⬨ Prevents / restores intestinal permeability.

ProButyrate is the brand I personally think is best due to it being in a fibrous matrix, meaning it has a better chance of making it to the colon where it can do its good.

600-1200 mg / day

tessmed.com/probutyrate/

15. B VITAMINS

All B vitamins 1-7 are critical mediators of energy production, the core of gut function. Improving energy metabolism in the gut will improve:

⬨ Motility
⬨ Stomach acid secretion
⬨ Digestive enzyme secretion
⬨ Immunity
⬨ Bacterial composition

I think getting a complex is a good place to start. This is the complex I prefer.

I think that it can be even more beneficial to try playing around with different combinations and doses.

It will probably serve you best to find your unique needs.

idealabs.ecwid.com/Energin-p70230…

Thiamine (B1) is especially important.

Forms like TTFD, benfotiamine and allithiamine are best.

Thiamine deficiency often manifests as gut problems.

This is the one I use, anywhere from 50 to 300 mg, start low and work your way up if no effect.

purebulk.com/products/benfo…

16. PREGNENOLONE:

⬨ Potent anti-stress
⬨ Lowers CRH, a critical gut inflammatory mediator
⬨ Other anti-inflammatory properties
⬨ Its metabolite allopregnanolone reverses IBS like symptoms, anti-serotonin

I take anywhere from 150-300 mg orally for this effect, even in higher doses it’s incredibly safe.

The only product I’ll ever use:

healthnatura.com/pregnenolone-2…

Gut issues can be quite difficult to figure out.

That’s why we started our consulting platform.

We have a team of practitioners if you are looking to optimize YOUR gut health.

Schedule a free consultation here to hear more! prism.miami

SORRY, LYSINE LINK HERE (posted magnesium link): purebulk.com/products/l-lys…

This thread was about practical application and is quite basic, so here are relevant threads that dive into more detail on many of the key concepts touched on here:

https://twitter.com/Outdoctrination/status/1677669968815456256

Thank you for reading along. Hopefully this was helpful and you can use this info to improve your health.

Toss us a RT if you’re so inclined, helps us a lot.

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