Vitamin B1 (thiamine) megadosing can massively reduce fatigue, in many cases reversing it entirely.

(🧵1/20) This study was a small pilot study conducted about a decade ago.

Anywhere from 600-1500 mg of B1 was used, depending on the weight of the patient.

The results were stunning.

10/12 patients had a complete reversal of fatigue.

The other two saw reductions by 50% and 66%.

(2/20)

A new study shows vitamin E can reverse fibrosis, inflammation and fat buildup in the liver.

(🧵1/7)
This study was published in Cell Medicine earlier this year.

Many studies have already shown that vitamin E has protective effects for the liver,

but this was the longest one to date (96 weeks) investigating this low of a dose of vitamin E - 300 mg of alpha tocopherol (450 IU) per day.

(2/7)

Red light therapy reverses all signs of skin aging, as shown in a recent study.

(🧵1/8) This study used red light therapy 2x a week for 3 months.

➔ 12 min / session
➔ 630 nm (red light wavelength)
➔ 15.6 J/cm^2 (power density)

with the Skin Light Dior × Lucibel mask.

(2/8)

A new landmark study has shown that eating meat is actually protective against cancer.

(🧵1/7) This study was published last month in the journal of Applied Physiology, Nutrition, and Metabolism.

There has been a lot of noise around the idea that animal protein can increase cancer and death risk, as one highly publicized studies from the 2014 suggested.

(2/7)

A disturbing new study shows that colon cancer tumors concentrate microplastics, and that nearly every colon tissue analyzed contains them.

(🧵1/6) Microplastics are tiny breakdown products of larger plastics, degraded by microbes, heat and other processes.

We are becoming progressively exposed to them in recent years.

This study was published this month, reviewing studies that looked at samples of:

➥ Colon cancer tumors
➥ Colon tissue from non tumor regions in cancer patients
➥ Colon tissue from people without cancer

(2/6)

A study shows that 2 cups of orange juice completely reverses many of the negative effects of a McDonald's meal.

(🧵1/8) This study was done in the American Journal of Clinical Nutrition.

They gave people either egg-muffin and sausage-muffin sandwiches and 2 hash-browns with:

➥ 75g straight glucose
➥ Water
➥ 2.5 cups of OJ

The OJ was not from concentrate, so pretty fresh.

(2/8)

Nicotine reverses signs of aging by reprogramming metabolism.

(🧵1/8) Nicotine has been understood for a while to have broad acting anti-inflammatory effects.

However, a recent study out of Nature showed that nicotine's impacts go far beyond reducing inflammation.

(2/8)

https://x.com/Outdoctrination/status/1897646839353975229

An interesting study demonstrates that a common animal based nutrient has powerful anti-aging properties.

(🧵1/6) This study was conducted in centenarians - people over the age of 100.

They implemented a supplement of L-Carnitine, a nutrient commonly found in animal foods like beef and eggs.

The research groups previous studies had shown carnitine could promote muscle mass and exercise performance in the elderly, but they wanted to test its ability to improve other measures of aging.

(2/6)

There's a 50% chance a parasite is in you right now.

Here's everything you know about them & how to protect yourself.

(🧵1/16) SIGNS of a parasite:

- Bloating
- Gas (especially after meals)
- Constipation or diarrhea
- Undigested food in stool
- Brain fog
- Anxiety or irritability
- Fatigue
- Iron-deficiency anemia
- Weight loss or unexplained weight gain
- Nutrient deficiencies despite eating well
- Histamine intolerance
- Food sensitivities
- Frequent infections
- Skin rashes or itching
- Muscle or joint pain

All of these symptoms can be indicative of, but are not exclusive to, parasites.

The KEY indicators that should make you think parasite over other factors:

☆ Itchiness - especially your butt
☆ Symptoms worsening at night (1-3 AM)
☆ Worsening at full moons
☆ Symptoms appear after traveling (esp to southeast Asia, Africa,
caribbean)
☆ Teeth grinding
☆ You see worms in your poop

(2/16)

The longest study to date has shown that aspirin has a powerful cancer preventing effect.

(🧵1/7) The study was published at the beginning of this year in The International Journal of Cancer.

It examined 1.5 million people in Hong Kong over 20 years.

Another similar study out of Denmark came shortly before this, showing no benefit of aspirin on cancer.

However, that study did not adjust for competing factors, such as dying from heart disease.

But given aspirin's many known beneficial impacts on cancer, it was time to re-investigate.

(2/7)

A recent study showed eye floaters can be substantially reduced with a few nutrients.

(🧵1/8) The study was published in 2021 in Translational Vision Science & Technology.

Floaters are incredibly common, and can be very bothersome.

People with them are often "willing to trade 1.1 years of every 10 years of their remaining life to get rid of their floaters."

Despite this, treatments are limited to expensive surgeries / lasers.

(2/8)

An astounding study shows that 1/2 a teaspoon of baking soda lowers inflammation within hours.

(🧵1/9) Study was published in 2018 in The Journal of Immunology.

Some experiment were done in rodents including baking soda in the water.

Some groups had their vagus nerves cut.

Other animals had a surgery to disturb the spleen.

Both surgeries were done to see if these tissues mediated the effect of baking soda.

Then, the human studies were done comparing drinking 2g of baking soda dissolved in water vs 2g of salt.

(2/9)

Glycine markedly improves sleep quality and daytime energy, with less than a teaspoon.

(🧵1/9) The first study investigating glycine and sleep came out in 2006.

Subjects taking 3g of glycine within an hour before bed reported:

➠ Substantially decreased fatigue the next day
➠ Improved subjective sleep quality

They also reported feeling:

➠ Very lively
➠ Extremely peppy
➠ Very refreshed
➠ More clear headed in the morning

(2/9)

A new study shows that a 1/3 of a clove of garlic reduces insulin resistance and even induces weight loss.

(and no, it's not just a correlation)

(🧵1/6) The study was published on August 6, in the Journal of Health, Population and Nutrition.

Researchers examined women with PCOS and insulin resistance, two conditions known to often go hand in hand.

(2/6)

A study has shown that DHEA replacement reverses several key signs of aging.

(🧵1/9) This study was published in the Journal of Aging.

DHEA levels decline by about 80% from age 25 to age 75.

Low levels of DHEA predict death.

Thus, researchers wanted to see if restoring it back to youthful levels could have a benefit.

(2/9)

https://x.com/Outdoctrination/status/1869105628280463649

A surprising new study showed that a LOW protein diet boosts metabolism and improves insulin sensitivity.

(🧵1/9) This study was published in Nature back in March.

There were a few phases.

1. Studying the immediate effects of an extremely low protein meal (high in carbs or high in fat)
2. Looking at the longer term (5 week) effects of a diet low in protein (high in either carbs or fat)

The low protein meals/diets had 8-9% calories from protein, high protein meals/diets had double that.

The high carb low protein diets had ~70% calories from carbs, ~20% fat.

The high fat low protein diets ~50% calories from fat, 40% carbs.

(2/9)

A new study shows that megadosing vitamin K2 improves liver cancer outcomes by up to 75%.

(🧵1/8)
The study was published in April in Nature (British Journal of Cancer).

It investigated people with existing liver cancer (hepatocelluar carcinoma).

People either got a targeted chemo surgery alone (TACE), or with 45 mg of menatetrenone (vitamin K2, MK-4).

Yes, milligrams - it is a megadose.

(2/8)

A groundbreaking new study shows that a mineral deficiency can drive Alzheimer's, and consuming it can reverse it.

(🧵1/10) The study was published 3 days ago, in Nature.

While lithium is used as a drug in high doses for things like bipolar disorder, it is a naturally occurring mineral in some foods and water supplies.

Unexpectedly, it seems to play a major role in Alzheimer's.

(2/10)

Magnesium rapidly reverses depression, often in under a week.

(🧵1/6) This was a short case series showing the incredible and fast turnaround of depressed patients with magnesium.

The first man experienced remission in around 4 days, taking 300 mg of magnesium taurate/glycinate multiple times daily.

A young woman was free of depression after one week of 200 mg of magnesium glycinate per meal.

A 40 year old man got off of cocaine and reversed his depression with 125 mg magnesium taurinate at each meal, again within a week.

(2/6)

Milk actually does make you taller.

(🧵1/7) Several studies have investigated the question.

In 1966, Japanese researchers stated that the reason why their people were short was due to a lack of calcium,

and that milk especially was the most important food for stimulating growth.

(2/7)

Several studies have revealed that zinc does indeed improve semen volume and testosterone, and have explained the science behind how it works.

(🧵1/7) It had been known since the 1920s that zinc was essential for proper reproductive function in animals.

Zinc was especially concentrated in the testes, and would rise during mating season.

The first study in humans (1977) showed that 100 mg of zinc daily could massively improve testosterone:

400 ng/dL ➜ 815 ng/dL in zinc group
547.5 ng/dL ➜ 320 ng/dL in control

It also lowered pituitary gonadotropins.

(2/7)