The power of GLYCINE is seemingly never-ending.

For something so cheap it has the power to literally extend lifespan, stop inflammation, heal your gut and send you into deep, restful sleep.

Let's get into the science, the incredible benefits & how to use it yourself (THREAD): Glycine increases lifespan, promotes longevity in animal studies.

8% increase in lifespan here.

☆ Anti-inflammatory
☆ Controls gene expression
☆ Clears homocysteine (toxic)
☆ Supports glutathione production (antioxidant)
☆ Precursor to creatine (muscle + brain fuel)
☆ Collagen synthesis
☆ Promotes autophagy

It counteracts the pro-aging effects of excess methionine, a major component of muscle meat.

Vitamin C can reduce cortisol by ~40%, according to a critical new study.

(🧵1/7) This study was published last year, examining the effects of 1g of vitamin C per day in people with high stress hormones.

Vitamin C is known to be stored in the adrenal glands and released in times of stress.

A few previous studies suggested adding vitamin C could lower cortisol.

(2/7)

Blocking / lowering prolactin stimulates hair growth AND reverses graying in early studies.

This is an antibody in trials right now that acts against the prolactin receptor.

What causes high prolactin?

◇ Prolactinomas
◇ High estrogen
◇ Low dopamine
◇ High serotonin
◇ Various stressors

https://x.com/Outdoctrination/status/2068480767760728222

more on estrogen

https://x.com/Outdoctrination/status/1928778977705079166

Orange juice is literally one of the healthiest foods on the planet.

It has proven antidepressant, anti-inflammatory, anti-diabetic and gut health promoting properties.

Don’t believe me? Let’s get into it: Orange juice has potent anti-inflammatory effects.

A McDonald’s meal causes inflammation from gut bacteria (endotoxin),

but this study showed having OJ with it:

- ELIMINATES increase in bacterial endotoxin
- Prevents inflammatory response.

Water could worsen the effects, but OJ halted them.

TAURINE might just be the missing link for optimal gut health, as a multifaceted anti-inflammatory and gut microbiome enhancing tool.

(🧵1/8) This study came out last year, and it showed something very important.

Taurine levels were markedly LOWER in people with inflammatory bowel diseases.

Both ulcerative colitis and Crohn's disease showed lower plasma levels of the amino acid.

BLOOD FLOW is so underrated + important.

Not only does it look sick, but it's vital for heart, cognitive and sexual health as well.

Here are 10 ways to optimize it (🧵): #1 Magnesium

Magnesium is an intracellular antagonist to calcium and glutamate, two excitatory signals that can drive excessive contraction / constriction of the vascular systems.

Magnesium can also partially reduce coagulation (blood thickening) by reducing inflammation.

Mastic gum has the power to improve cavities, gingivitis, reduce dental plaques and has even been called a "potent antitumor agent" for oral cancer.

(🧵1/7) Mastic gum is made from the resin of the tree Pistacia lentiscus.

It's been used for over 2,000 years medicinally for various reasons,

but notably, it has some key antibacterial and anti-cancer properties, especially in the mouth.

A quick and easy way to lower stress and inflammation: HUMMING.

Humming is one of many ways that you can activate your parasympathetic nervous system through the VAGUS NERVE, completely for free.

Here are some other ways, and how they can benefit your health (🧵1/6):

https://x.com/Outdoctrination/status/2043712196132446395

Method #2: Diaphragmatic Breathing

This type of deep breathing results in structural changes throughout the abdominal cavity, diaphragm and esophagus.

This ends up directly stimulating the vagus nerve.

BPC-157 is one of the most famous peptides out there - with claims it's a borderline miracle cure for anything you can name.

Here's everything we know (& more importantly, don't know) about how it works (🧵1/10): BPC-157 is called such because it is literally known as "Body Protection Compound."

It's a string of 15 amino acids. It's also known as "stable gastric pentadecapeptide" because it doesn't break down much in stomach acid.

It is a synthetic peptide, but its structure is derived from a protein found naturally in the stomach.

Zinc has been called "The Wonder Drug for the Treatment of Cancers (Carcinomas)" by some researchers - and this is why: (🧵1/8)

https://x.com/Outdoctrination/status/1969795169529495952

What stands out first is that it's extremely common for zinc levels to be lower in cancerous tissue than in healthy tissue.

This is most exemplified in prostate cancer - across these studies an average decrease of over 60% in zinc levels.

Coconut oil has surprisingly potent antifungal properties, even against Candida.

(🧵1/8)

https://x.com/Outdoctrination/status/1912147168322109742

Coconut oil is a powerful antifungal, more than the leading drug fluconazole, in vitro.

Yep.

In cultured cells, coconut oil outperformed the standard antifungal prescription medication.

Autism is a mitochondrial disorder - and restoring their function can improve it, demonstrated beautifully in a recent trial.

(🧵1/8)
Mitochondrial dysfunction is any abnormality in this organelle's ability to generate energy or other substrates.

Depending on the criteria, anywhere from 5% up to 90% (in this study) of people with autism spectrum disorders suffer from some form of mitochondrial dysfunction.

Thus, the goal in this study was to identify that subset and treat accordingly.

You can literally clean out your brain by doing this.

It accumulates waste that makes you tired and ends up giving you dementia.

Luckily, these 7 techniques enhance its clearance to help keep your mind sharp.

#1 Sleeping on your side Side sleeping helps by:

◇ Allowing gravity to help move cerebrospinal fluid
◇ Reducing intracranial pressure
◇ Improving blood flow through the neck and head

This stimulates the clearance of the glymphatic system

Lactoferrin has "potent anti-obesity" effects, reducing visceral fat substantially within a few weeks, according to a remarkable study.

(🧵1/7)

https://x.com/Outdoctrination/status/2002518879386390678

This study came out in 2010 in the British Journal of Nutrition.

People were enrolled who had:

◈ BMI >25 kg/m2
◈ Visceral fat area >100 cm²

So they were "considered to be visceral fat-type obese, but had not been treated at an out-patient department and had no serious disease."

For those of you who don't know, visceral fat is the type of fat that accumulates around the organs and is much more inflammatory and metabolically dangerous.

They were given 300 mg of enteric coated lactoferrin per day for 8 weeks (or placebo).

A fascinating study showed that Vitamin E nearly doubles testosterone in response to stimulation, and by over 100 points at baseline.

(🧵1/8) Subjects were restricted to eating the diet the hospital put them on, with a consistent amount of vitamin (3-5 mg).

They were then put on 483 mg (724.5 IU) of vitamin E for 8 weeks.

This is a huge dose - over 30X the "recommended" daily amount.

It was also vitamin E acetate - a relatively poorly absorbed form of the vitamin.

(2/8)

Zinc can help shed body fat - independently of calories, multiple clinical trials have shown.

(🧵1/7) This study put people on weight loss diets of roughly ~300 calories fewer than baseline.

They were all overweight / obese measured by BMI.

30 mg of zinc as zinc sulfate or placebo was given in either group. This was done because zinc is a common deficiency in obesity.

15 weeks later, they found some astounding results.

Taurine is one of the most important nutrients for the brain, serving a number of protective roles in cognitive aging and stroke.

(🧵1/7)
I was surprised to find out that taurine is actually the second most abundant amino acid in the central nervous system, behind glutamate.

Taurine levels in both the cerebrospinal fluid and certain brain regions are lower in people with Alzheimer's disease.

This has important consequences.

Low dose naltrexone is legitimately a life changing drug for many - its anti-inflammatory benefits are able to help in a multitude of conditions. Let's talk about it. (🧵1/8) Naltrexone is classically an opioid antagonist.

At its normal doses (50-100 mg) it's used to block opioid signaling in conditions like addiction, which reduces dopamine output from drugs.

This makes it easier to get off the drugs.

However, when used at lower doses it has some amazing other actions.

Vinegar at ~1 tbsp reduces insulin response by up to 50% across multiple trials, a review article concluded.

(🧵1/8) This first paper is a review article from 2017.

They looked at studies giving people vinegar alongside meals and monitored their blood sugar and insulin responses.

Having high levels of these post meal is highly indicative of insulin resistance and is a risk for heart disease.

Apologies, I do not have the official PDF so I'm working with the raw file here.

The vitamin that NEVER gets talked about has more benefits than you can even count.

Mental health, boosting metabolism, gut health and even increasing testosterone.

Let's talk about the marvelous VITAMIN K2: This study showed that Vitamin K2 could treat depression.

K2 (as MK-7) improved depression at just 90 ug/day, a pretty puny dose, in 8 weeks.

K2 fulfills multiple roles in the body that gives it this effect.

The effect is very noticeable in my experience, it's an instant mood lifter.

Magnesium is often a missing link in tinnitus - and supplementing it can alleviate the ringing sensation. (🧵1/8) A short report in 2016 showed that serum magnesium levels were lower in people with tinnitus.

Keep in mind this was serum levels, typically the last place for magnesium to become depleted in.

But is this correlation or something real?