BDNF is a protein that has been called "Miracle-Gro for the brain."

It literally creates new brain cells and strengthens the ones you already have.

Here are 5 ways to boost it:

#1 Red light therapy

Red light has recently been shown to benefit cognitive decline, and increase BDNF.
Red light works through multiple mechanisms to stimulate BDNF.

➥ Increased mitochondrial function
➥ Improved blood flow
➥ Lessened oxidative stress
➥ Lower inflammation

More on that below.

https://x.com/Outdoctrination/status/1905260729843789847

Wrinkles and other signs of skin aging can be reversed with an oral supplement of astaxanthin, a critical study concludes.

(🧵1/8)

https://x.com/Outdoctrination/status/1960308711282344416

Astaxanthin is a powerful antioxidant found in red seafood like salmon and shrimp.

If you're unfamiliar, I've written more about what it is below.

This study pooled together all of the human studies done on astaxanthin.

Let's go through them.

(2/8)

https://x.com/Outdoctrination/status/1932422607154098659

Cavities are prevented / reversed with a new toothpaste formulation that outperforms conventional fluoride without toxicity, a new study confirms.

(🧵1/8) Your tooth enamel are essentially crystals.

These repeating patterns of different minerals and ions.

When the mouth is acidic, these structures dissolve and the enamel degrades, forming cavities.

These crystals are composed of hydroxyapatite units.

What fluoride does is replaces the hydroxide with fluoride.

So you're replacing your body's natural mineral structure with an artificial mineral structure.

(2/8)

LOW CARB diets might actually WORSEN cancer progression + outcomes, contrary to popular belief, according to a recent study.

Let's unpack this one (🧵1/8) While it is true that carbs (glucose) fuel cancer cell growth,

growth of tumors is not the only piece to the puzzle.

If low carb metabolism actually promotes the SPREAD of cancer, that's much worse since this is the main cause of death in cancer.

They found that out of 22 cancers analyzed, LOW glucose metabolism was correlated / possibly correlated with 15 of them.

(2/8)

BLOOD FLOW is so underrated + important.

Not only does it look sick, but it's vital for heart, cognitive and sexual health as well.

Here are 10 ways to optimize it:

https://x.com/Outdoctrination/status/1977744364244812001

#1 Magnesium

Magnesium is an intracellular antagonist to calcium and glutamate, two excitatory signals that can drive excessive contraction / constriction of the vascular systems.

Magnesium can also partially reduce coagulation (blood thickening) by reducing inflammation.

STOP focusing on cholesterol for heart disease.

Your doctor doesn't realize it's only a small part of the process of developing heart disease.

Here's a DEEP dive into how heart disease develops, what to do about it, & why focusing solely on cholesterol is a path to an early death: Let me start off by saying cholesterol IS important to the process of plaque buildup in the arteries (atherosclerosis).

HOWEVER, it is a disservice and likely harmful to focus solely on it, for a few reasons.

First being, about half of people who get heart attacks don't even have high cholesterol.

MOLD. HEAVY METALS. ENDOCRINE DISRUPTORS. GLYPHOSATE.

If you are struggling with toxins, you need a solid foundation.

Here are the MOST IMPORTANT NUTRIENTS your body needs to optimize its DETOXIFICATION processes: MOLYBDENUM: a nutrient you’ve never heard of, but is critical for detoxification.

Molybdenum helps convert the toxic sulfite into sulfate.

We NEED sulfate for detoxification.

Molybdenum cofactor deficiency = rapid brain damage

Best food sources: beef liver, pasta, rice.

ZINC reverses depression, and its deficiency causes it, confirmed in a critically important review study.

Here's exactly why + how to make sure you're covered.

(🧵1/9) The association between zinc status and mood disorders is undeniable.

Older review studies have shown that zinc levels are consistently and markedly lower in people with depression.

In fact, there is a tight correlation between low zinc levels and depression severity.

(2/9)

Autoimmune diseases CAN be healed, if you know how to approach them properly.

Here are 10 KEY CAUSES of autoimmunity - and what to do about them: 1. LEAKY GUT.

Intestinal permeability leads to inflammation systemically, skewing T cells away from anti-inflammatory to pro-inflammatory types.

Roughly 80% of your immune system is in the gut, and if it's off it is perhaps the primary trigger of autoimmunity.

The keys to longevity were recently uncovered in a groundbreaking study on the world's longest lived person.

(🧵 1/8) This was by far the most comprehensive study ever done on a super-centenarian (>110 years old).

One of the first key takeaways was that her telomeres, which are thought of as protective barriers on the ends of your genetic material, were incredibly short.

Typically longer telomeres are considered good, but apparently they didn't matter for her.

(2/8)

Lion's mane mushrooms powerfully stimulate the growth and function of brain cells.

This gives them anti-depressant / anti-anxiety and cognitive enhancing properties.

(🧵1/8) This 2019 article investigated the impacts of a Lion's mane mushroom extract (500 mg) on various markers of mental health.

The researchers found several significant benefits of the shrooms.

(2/8)

Drinking coffee with milk has the power to extend lifespan & reverse aging of the brain, as the classic combo was recently tested experimentally.

(🧵1/7) This study investigated the impacts of coffee + milk components on aging animals, specifically in the brain.

They started giving these components to the animals at a relatively young age.

(2/7)

AI is already outperforming doctors, and how it does so illuminates how optimal health will be achieved in the future.

(🧵1/8) The aim of this study was to provide TARGETED plans for people trying to lose fat.

The researchers point out that typical "eat less move more" advice is not only generic and does not address unique root causes,

but also has poor results.

They aimed to invoke AI to help.

(2/8)

Fresh orange juice was able to reverse clinical depression & improve gut health with a few cups a day, a recent study has demonstrated.

(🧵1/7) This study was published in 2022 examining the effects of flavonoid rich orange juice on depression and gut health.

The flavonoid rich juice was Natalie's brand from Florida.

The flavonoid poor juice was orange flavored cordial.

Roughly 2.5 cups a day for 8 weeks.

(2/7)

GREY HAIR was improved by over 50% using a mix of natural ingredients, as showcased in a landmark new study.

(🧵1/8) This study was published earlier this year.

It took subjects experiencing hair loss conditions and gave them a product of:

◇ Redensyl - a mix of flavonoids and nutrients
◇ Oryza sativa (rice) water extract
◇ Salvia hispanica (chia) seed extract
◇ Rosemary oil
◇ MelanoGray - a different mix of flavonoids and nutrients
◇ AnaGain - based on pea and pea sprout extract

for 4 months.

(2/8)

WANT TO LIVE LONGER?

Here are 5 of the main DRIVERS OF AGING you need to take control of (🧵1/10):

#1 High iron

Iron depletion reduced the risk of death by 65% in heart disease.

Most people think they are low on iron when nothing could be further from the truth. Many drugs that prolong lifespan in animals also chelate (minimize) iron.

Iron has a propensity to build up in tissues and lead to inflammation and damage.

Though iron deficiency is possible, a full lab workup of:

◇ Ferritin
◇ Serum iron
◇ TIBC
◇ Transferrin + % saturation
◇ CBC

+ potentially others should be done to correctly assess anemia, not just assuming iron deficiency.

(2/10)

Chronic fatigue can be substantially improved with a cheap, over the counter supplement, according to several recent studies.

(🧵1/6)
Coenzyme Q10 (CoQ10) is a molecule ubiquitous in our bodies, and in some animal foods like beef heart.

Research has shown that plasma levels of CoQ10 are markedly lower in those with:

◆ Depression
◆ Chronic fatigue syndrome

and these levels predict the severity of these conditions.

In other words, the lower your CoQ10, the more depressed and fatigued you'll be.

(2/6)

Will putting red light on your balls triple your testosterone?

The science might surprise you.

(🧵1/8) As it turns out, multiple animal studies have shown benefits of red / near infrared light applied to the testes.

Here is one study, examining the benefits of a red laser to the balls of animals with spinal cord injury, which impairs testicular function and thus testosterone.

The light increased testosterone - at 810 nm.

(2/8)

A new study has shown that folate (vitamin B9) megadosing can substantially improve autism.

(🧵1/8) Children with autism were assigned to either vitamin B9 (folate) megadoses (2mg / kg / day, maximum 50 mg) for 12 weeks.

These children also got genotyped for key genes involved in folate metabolism.

Children with autism often have genetic impairments in proteins involved in the proper utilization of folate.

(2/8)

Zinc carnosine rapidly and powerfully reduces gut inflammation + heals digestion, even in severe cases.

(🧵1/7) Zinc is known to be depleted in inflammatory bowel conditions,

and its levels directly are correlated with the severity and stage of the disease.

Worse inflammation = lower zinc, universally.

Zinc carnosine is a special form of zinc used overseas for various digestive ailments.

(2/7)

A striking study has demonstrated that vitamin B3 can reverse every sign of skin aging within a few weeks.

(🧵1/8) They used a form of vitamin B3 called niacinamide, which is a derivative of niacin or nicotinic acid - the standard form we get from food.

This form of B3 gets more efficiently converted into a molecule called NAD+, which is where much of vitamin B3's activity lies.

People applied a "pea sized" amount of 5% niacinamide to the face 2x a day.

(2/8)