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Mar 22 โ€ข 3 tweets โ€ข 1 min read โ€ข Read on X
๐—ž๐—ฒ๐˜† ๐—ฆ๐˜๐˜‚๐—ฑ๐˜† :
"๐—œ๐—ป๐—ฐ๐—ฟ๐—ฒ๐—ฎ๐˜€๐—ฒ๐—ฑ ๐—ณ๐—ฎ๐—ฒ๐—ฐ๐—ฎ๐—น ๐˜€๐—ต๐—ฒ๐—ฑ๐—ฑ๐—ถ๐—ป๐—ด ๐—ถ๐—ป ๐—ฆ๐—”๐—ฅ๐—ฆ-๐—–๐—ผ๐—ฉ-2 ๐˜ƒ๐—ฎ๐—ฟ๐—ถ๐—ฎ๐—ป๐˜๐˜€ ๐—•๐—”.2.86 ๐—ฎ๐—ป๐—ฑ ๐—๐—ก.1"

H/t @SukunaBikona7

"Concerns persist that JN.1 might have an increased capacity to replicate in the gut, thelancet.com/journals/laninโ€ฆ
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2) ...potentially leading to infected individuals shedding a higher number of viral copies than previously seen."

Fig. Faecal shedding and symptoms data for 113 individuals infected with XBB.1.5 (n=19), EG.5.1 (n=18), HV.1 (n=18), JD.1.1 (n=17), BA.2.86 (n=16), and JN.1 (n=25) Image
3) "Taken together, we provide evidence confirming that both BA.2.86 and JN.1 show higher rates of viral shedding compared with XBB.1.5, EG.5.1, HV.1, and JD.1.1, including in presymptomatic and vaccinated individuals, which might partly explain the increase in wastewater levels"

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More from @ejustin46

Mar 23
A wonderful study ๐Ÿ‘ :
๐—ฃ๐—˜๐—ข๐—ฃ๐—Ÿ๐—˜ ๐—ฎ๐—ฟ๐—ฒ ๐—ฎ๐—ป ๐—ข๐—ฅ๐—š๐—”๐—ก๐—œ๐—– ๐—จ๐—ก๐—œ๐—ง๐—ฌ : ๐™‚๐™ช๐™ฉ-๐™ก๐™ช๐™ฃ๐™œ ๐™–๐™ญ๐™ž๐™จ ๐™–๐™ฃ๐™™ ๐™ฅ๐™ฃ๐™š๐™ช๐™ข๐™ค๐™ฃ๐™ž๐™–

cell.com/heliyon/fullteโ€ฆ
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2) "People are an organic unity. Every organ of our body doesn't exist alone. They are a part of our body and have important connections with other tissues or organs. The gut-lung axis is a typical example. Here, we reviewed the current research progress of the gut-lung axis."
3) Fig. Immune crosstalk of gut-lung axis. Immune cells such as DCs and lymphocytes are activated by intestinal microbes and enter lymphatic and blood circulation through mesenteric lymphatics and portal vein system, and finally enter the lung to play an immunomodulatory role. Image
Read 18 tweets
Mar 23
๐—ž๐—ฒ๐˜† ๐˜€๐˜๐˜‚๐—ฑ๐˜† !

nature.com/articles/s4159โ€ฆ
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2) "The impact of mechanical ventilation on airborne diseases is not completely known. The current study focused on a hospital lift where two subjects were included: a healthy passenger and an infected one.
Three ventilation strategies were evaluated: a without ventilation case, Image
3) ... an upwards-blowing exhausting fan case and a downwards-blowing fan case. 5 seconds after the elevator journey began, the infected person coughed. For the risk assessment, the CO2 concentration, droplet removal performance and dispersion were examined Image
Read 9 tweets
Mar 23
๐—ช๐—ต๐—ฎ๐˜ ๐—ถ๐—ณ ๐˜„๐—ฒ ๐˜„๐—ถ๐—น๐—น ๐—ป๐—ฒ๐˜ƒ๐—ฒ๐—ฟ ๐—ณ๐˜‚๐—น๐—น๐˜† ๐—ฟ๐—ฒ๐—ฐ๐—ผ๐˜ƒ๐—ฒ๐—ฟ ๐—ณ๐—ฟ๐—ผ๐—บ ๐—ฎ๐—ป ๐—ถ๐—ป๐—ณ๐—ฒ๐—ฐ๐˜๐—ถ๐—ผ๐—ป?

thorax.bmj.com/content/early/โ€ฆ
Image
2) "Cohort studies of COVID-19 survivors demonstrate that incomplete recovery, persistent symptoms and disability are common after the initial infection. Persistent CT scan abnormalities have been documented 1 year following COVID-19 infection, especially among older adults." Image
3) "We conducted a prospective single-centre cohort study of 104 multi-ethnic severe COVID-19 survivors from the first wave of the pandemic 15โ€‰months after hospitalisation. Of those who were assessed at 4 and 15โ€‰months, improvement of ground glass opacities ... Image
Read 5 tweets
Mar 23
๐—ž๐—ฒ๐˜† ๐˜€๐˜๐˜‚๐—ฑ๐˜† : ๐—ฆ๐—”๐—ฅ๐—ฆ-๐—–๐—ผ๐—ฉ-2 ๐—ถ๐—ป๐—ณ๐—ฒ๐—ฐ๐˜๐—ถ๐—ผ๐—ป ๐—ถ๐—ป๐—ฐ๐—ฟ๐—ฒ๐—ฎ๐˜€๐—ฒ๐˜€ ๐˜๐—ต๐—ฒ ๐—ฟ๐—ถ๐˜€๐—ธ ๐—ผ๐—ณ ๐˜„๐—ผ๐—ฟ๐˜€๐—ฒ ๐—ผ๐˜‚๐˜๐—ฐ๐—ผ๐—บ๐—ฒ๐˜€ ๐—ถ๐—ป ๐—ฐ๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฟ ๐—ฝ๐—ฎ๐˜๐—ถ๐—ฒ๐—ป๐˜๐˜€, ๐—ถ๐—ป๐—ฐ๐—น๐˜‚๐—ฑ๐—ถ๐—ป๐—ด ๐˜๐—ต๐—ผ๐˜€๐—ฒ ๐˜„๐—ถ๐˜๐—ต ๐—ฏ๐—ฟ๐—ฒ๐—ฎ๐˜€๐˜ ๐—ฐ๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฟ ๐Ÿ˜ฐ๐Ÿ˜ฐ๐Ÿ˜ฐ
frontiersin.org/journals/oncolโ€ฆ
Image
2) "Our previous study reported that the SARS-CoV-2 membrane protein (M-protein) promotes the malignant transformation of triple-negative breast cancer cells (triple-negative BCC)."
3) In the present study, the effects of M-protein on the ability of extracellular vesicles (EV) derived from triple-negative BCC to regulate the functions of tissue stem cells facilitating the tumor microenvironment were examined. Image
Read 8 tweets
Mar 23
๐—Ÿ๐—ฌ๐— ๐—˜ ๐——๐—œ๐—ฆ๐—˜๐—”๐—ฆ๐—˜ + ๐—ฆ๐—”๐—ฅ๐—ฆ-๐—–๐—ข๐—ฉ-2, ๐˜๐—ต๐—ฒ ๐—•๐—”๐—— ๐—–๐—ข๐— ๐—•๐—œ๐—ก๐—”๐—ง๐—œ๐—ข๐—ก!


"Borrelia burgdorferi, the spirochetal agent of Lyme disease, utilizes a variety of strategies to evade and suppress the host immune response ... journals.asm.org/doi/10.1128/iaโ€ฆ
Image
2) ... which enables it to chronically persist in the host.
Here, we show that mice infected with B. burgdorferi and concomitantly immunized with SARS-CoV-2 spike protein had an abrogated antibody response to the immunization. Image
3) "Host antibody production against the SARS-CoV-2 spike protein returned to baseline following antibiotic treatment; however, anti-SARS-CoV-2 IgM remained high, comparable to levels found inย B. burgdorferi-infected but untreated mice. Image
Read 4 tweets
Mar 22
๐—•๐—”๐—•๐—ฌ ๐—–๐—ข๐—ฉ๐—œ๐—— ! ๐Ÿ˜ฐ
๐™ƒ๐™–๐™จ ๐™ฉ๐™๐™š ๐™ฌ๐™ค๐™ง๐™ก๐™™ ๐™œ๐™ค๐™ฃ๐™š ๐™ข๐™–๐™™?


There are studies that I hesitate or refuse to post.
But faced with those who deny the pandemic, do we have a choice? publications.aap.org/pediatrics/artโ€ฆ
Image
2) This study focuses on babies (infants aged 0 to 90 days) with suspected SARS-CoV-2 infections.

"Among 1048 infants tested for SARS-CoV-2, 432 (41.2%) were SARS-CoV-2โ€“positive and 616 (58.8%) were SARS-CoV-2โ€“negative.
Overall, 28 (2.8%) were noted to be moderately Image
3) ... or severely ill at presentation. There were 373 (35.6%) who underwent additional viral testing besides SARS-CoV-2, and other viruses were detected among 16 of 143 (11.2%) SARS-CoV-2โ€“positive and 82 of 230 (35.7%) SARS-CoV-2โ€“negative infants.
Read 6 tweets

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