Thread by @Outdoctrination

Modern medicine’s greatest contribution to the health of mankind.

It heals cancer, depression and is even a nootropic.

And it’s safe and cheap to boot.

Why ASPIRIN is so much more than a painkiller and a blood thinner:

What if I told you that a treatment that costs literally one nickel per day could completely reverse an otherwise deadly liver cancer?

Aspirin did that.

In fact, aspirin has consistently and unequivocally shown to reduce both the incidence AND the mortality of various cancers.

But that’s just scratching the surface of what it can do.

ASPIRIN is the lifespan extending intervention that everyone has been searching for.

It has consistently been shown to reduce the risk of dying from any cause, demonstrating its broad ranging protective effects.

Aspirin’s primary metabolite IMPROVES insulin resistance, a common underlying factor behind almost EVERY disease you can think of.

◦ IMPROVES glucose metabolism
◦ REDUCES blood sugar
◦ REDUCES C peptide (insulin)
◦ Improves inflammatory markers

Aspirin’s ability to treat diabetes dates back over 100 years, with doctors in the late 1800s and early 1900s showing that aspirin metabolites could completely halt the excretion of sugar into the urine.

One of the KEY benefits of aspirin is its ANTI STRESS properties.

Many people report calmness and better sleep on aspirin, and this is likely a prime reason why.

Aspirin can actually lower the output of cortisol, our primary stress hormone, at baseline.

Aspirin ALSO lowers cortisol release in response to various stressors, allowing us to avoid some of the deleterious effects of excess stress in these situations.

Post exercise this can be very valuable if you’re completely drained or wired.

Aspirin seems to actually suppress the response of prolactin to stressors.

Prolactin is probably best known for being that feeling after ejaculation for men, opposing dopamine and giving this lethargic and unmotivated type of feeling.

In fact, aspirin has incredible mood enhancing effects.

One study showed that aspirin REVERSED depression in over half of patients.

On average, it cut their symptoms in half, the majority of which happened within one week.

Half of a standard tablet.

Aspirin has also been shown to act as a nootropic.

Elevated serotonin in the brain can cause neurological abnormalities, but aspirin counteracts this.

Use of aspirin has been shown to dramatically cut down the risk of developing dementias, cutting some down by over half!

Aspirin has some strikingly potent effects on the brain.

⬨ It increases BDNF, responsible for growth of new brain cells
⬨ It increases neural plasticity in memory and higher thinking brain regions

In turn, it improves memory and cognition, again at lower doses.

Aspirin’s benefits on the brain extend to its ability to prevent and treat migraines.

Inflammation is an absolute killer.

If you’re just generally tired, aspirin can be a good tool in the arsenal.

It’s been shown to counteract fatigue, and in my experience can perk you up if you’re just not feeling it.

Aspirin’s ability to counteract tiredness is related to its ability to stimulate mitochondrial energy production at low doses (baby aspirin).

The main aspirin metabolite, salicylic acid, also prevents the structural and functional breakdown of the mitochondria over time.

Aspirin actually can counteract ESTROGEN as well.

Aspirin is an aromatase inhibitor, and can lower levels of estrogen.

Excess estrogen can give you love handles, that “tired but wired” type feeling, among other things.

Just 100 mg (little over a baby aspirin) daily.

This is the aspirin powder I use, it is PURE and not full of additives like many commercial brands you see in the store.

These additives may in fact be why aspirin gets a bad rep to begin with. healthnatura.com/aspirin-powder…

If you don’t believe me, read this

https://twitter.com/Outdoctrination/status/1743359958068998483

But how is this all possible?

Aspirin is so therapeutic for such a wide range of ailments because it acts on such basic and fundamental pathways in human health.

‣ Energy production and metabolism
‣ Inflammation, specifically the production of prostaglandins

Prostaglandins are inflammatory mediators derived from dietary polyunsaturated fats, which directly drive processes like:

- Stress
- Pain
- Metabolic suppression
- Estrogen production

Just to name a few, which can drive all types of issues, from mood to energy problems.

Critically, prostaglandins promote the release of fat from the fat tissue.

While this may sound like a good thing, excessive dumping of these lipids into the blood contribute directly to

- Insulin resistance
- Organ toxicity

Aspirin counteracts this process.

Aspirin also prevents oxidative damage, a central process in every disease driven by dietary polyunsaturated fats.

Low dose aspirin may be some of your best protection if you’ve been eating high amounts of these fats (aka seed oils) for some time.

A very recent study showed that aspirin is able to combat fatty liver disease, which is a huge plague that is starting to affect nearly everyone.

Aspirin also has incredible antibacterial and antifungal effects, even against candida, capable of disrupting biofilm formation that makes it so stubborn and difficult to get rid of.

Now, aspirin is absolutely incredible, but of course there are precautions and potential risks you all should be aware of.

As mentioned previously, getting a high quality / pure brand is paramount, since much of the issues using aspirin arise from additives common in low quality versions.

The big concern is around the effects of aspirin on bleeding, especially in the gut.

As someone who has struggled with gut issues in the past and puts a ton of emphasis on gut health, I’m extremely cautious about anything involving the gut.

I believe that the narrative is a bit misconstrued.

First, the risk seems to be massively overblown. The risk of a placebo causing GI bleeding is around 5 in 1000, and it is 8 in 1000 for aspirin use. On top of this, aspirin actually seems to protect against the fatal, more serious type of gut bleeding.

Second, there are a few measures you can take to avoid this. Dissolving it in water helps avoid having it concentrated in one patch of your gut. Adding glycine (2:1 aspirin to glycine, sold as Glyprin) and baking soda (⅓ teaspoon) also completely protect against these issues.

Lastly, this seems to be transient, with the gastric mucosa adapting in just a few days to aspirin.

Importantly, at very high doses (multiple grams), aspirin tends to actually suppress mitochondrial energy production, the opposite of what it does at the lower doses (<160 mg).

Some like the higher doses for specific reasons, like cancer, or for more potent blood sugar or anti-stress effects.

It’s not that you can’t use higher doses, but it is something to be aware of.

If you want some personalized coaching in optimizing your metabolism, schedule a free consult with us here to hear more about how we can help you! prism.miami/get-started

Thank you for reading along. Hopefully this was helpful and you can use this info to improve your health.

Toss us a RT if you’re so inclined, helps us a lot.

Be sure to check out all of our content and supplements, as well as ways to donate, over at lnk.bio/analyze.and.op…