"The COVID-19 pandemic heightened risks for individuals with hematological malignancies due to compromised immune systems, leading to more severe outcomes and increased mortality. " thelancet.com/journals/eclinโฆ
2) "The EPICOVIDEHA registry collected data from January 2020 to December 2022, involving 8767 COVID-19 cases in hematological malignancy patients from 152 centers across 41 countries, with 42% being female. Over this period, there was a significant reduction ...
3) ... in critical infections and an overall decrease in mortality from 29% to 4%. However, hospitalization, particularly in the ICU, remained associated with higher mortality rates."
4) Fig. COVID-19 severity prevalence and mortality rate, overall mortality rate, mortality per malignancy status at COVID-19 onset, and mortality per reason for mortality.
5) Fig. COVID-19 severity prevalence and mortality rate, overall mortality rate, mortality per malignancy status at COVID-19 onset, and mortality per reason for mortality.
6) Fig. Survival probability per diagnosis semester, vaccination status, and COVID-19 treatment. A
7) Fig. Survival probability per diagnosis semester, vaccination status, and COVID-19 treatment.
8) ๐๐ก๐ง๐๐ฅ๐ฃ๐ฅ๐๐ง๐๐ง๐๐ข๐ก
"Patients with hematological malignancies still face elevated risks, despite reductions in critical infections and overall mortality rates over time. Hospitalization, especially in ICUs, remains a significant concern. The study underscores ...
9) ... the importance of vaccination and the timing of COVID-19 exposure in 2022 for enhanced survival in this patient group. Ongoing monitoring and targeted interventions are essential to support this vulnerable population, emphasizing the critical role of timely diagnosis ...
10) ... and prompt treatment in preventing severe COVID-19 cases."
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NIPAH VIRUS
Jumping to conclusions during outbreaks only fuels panic and misunderstanding; NOT EVERY VIRUS OUTBREAK is a PANDEMIC.
We raised the alarm about Nipah in 2023, but itโs essential not to confuse an epidemic related to this virus, ...
2) ...like the one in India, with a pandemic risk or a situation like COVID-19.
Nipah virus is transmitted primarily from animals, especially bats, to humans. It spreads through direct contact with infected animals, their secretions, or contaminated foods.
3) Human-to-human transmission occurs only through close contact, such as touching or caring for an infected person, as well as sharing fluids like saliva or blood.
We cannot equate a virus transmitted through fluids with a respiratory virus like SARS-CoV-2.
"70% to 90% of our CELLS are completely RENEWED in less than 5 YEARS!
So If weโre mostly "New", why are so many still struggling with SARS-CoV-2?
We will tackle this question, which is more complex than it seems, in several posts.
2) First, let's say a few words about cell renewal.
70% to 90% of our cells are renewed over time. This turnover occurs in various cell types, including skin, blood, and immune cells, allowing the body to replace damaged or aged cells. sciencefocus.com/the-human-bodyโฆ
3) For instance, red blood cells have a lifespan of about 120 days, while skin cells regenerate every few weeks.
Even with significant cell renewal, aging persists due to changes in our DNA. sciencefocus.com/the-human-bodyโฆ
2) Co-infection occurs when a person is infected by more than one virus at the same time. This can lead to interesting and sometimes complex interactions between the viruses
3) In one study about SARS-CoV-2, researchers found that when different versions of this virus infect the same person, they can mix their genetic material through a process called recombination. This means that the new version of the virus can have traits from both parent viruses
For more than three years, we have been emphasizing that the envelope protein is an essential component and that we cannot limit our focus to just the spike protein. We are now uncovering its role in long COVID.
3) The Envelope (E) protein of SARS-CoV-2 plays a crucial role for several reasons:
โถ๏ธ Virus Assembly and Release: The E protein is essential for the virus's assembly and budding from infected cells, contributing to its stability and infectivity.
"N''oubliez jamais" (Never forget - Joe Cocker)๐งต
In 2022, COVID-19 was the second leading cause of death globally, with the repercussions of the virus far from over. The lasting impact of the pandemic continues to affect lives around the world.
Recent research may have identified a key factor contributing to long COVID: microscopic clots intertwined with immune system debris in the blood. These unusual structures were found to be nearly 20 times more prevalent ...
2) ...in long COVID patients compared to healthy individuals. The clots, associated with neutrophil extracellular traps (NETs), suggest a potential biological marker for persistent symptoms.
3) These microclots could impede blood flow in small vessels, leading to issues like brain fog, fatigue, and shortness of breath.