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Apr 3 โ€ข 10 tweets โ€ข 4 min read โ€ข Read on X
20 ๐˜๐—ผ 85% ๐—”๐—ฆ๐—ฌ๐— ๐—ฃ๐—ง๐—ข๐— ๐—”๐—ง๐—œ๐—–๐—ฆ ๐—ฎ๐—ฐ๐—ฐ๐—ผ๐—ฟ๐—ฑ๐—ถ๐—ป๐—ด ๐˜๐—ผ ๐˜€๐˜๐˜‚๐—ฑ๐—ถ๐—ฒ๐˜€. ๐—ช๐—ต๐˜† ๐˜€๐˜‚๐—ฐ๐—ต ๐—ฎ ๐——๐—œ๐—™๐—™๐—˜๐—ฅ๐—˜๐—ก๐—–๐—˜?

There are 3 biases that we see in studies:
โ–ถ๏ธ Some asymptomatics are actually pre-symptomatic.
โ–ถ๏ธ Some studies focus on a small or categorized sample
2) ... (population with cancer, renal dialysis, neonatal, etc.)
โ–ถ๏ธ The severity of the symptoms is sometimes difficult to assess (slight fever or slight cough is a symptom of COVID).
We can see these differences ranging from 22 to 85% depending on the studies. Image
3) The previous table comes from a mega-analysis by Eric Topol, which gave a median rate of 41% of asymptomatic people.
ncbi.nlm.nih.gov/pmc/articles/Pโ€ฆ
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4) We have taken all the studies, limiting ourselves to the one published in 2024, like this one for Hong Kong. Here the asymptomatic rate is 75%
wwwnc.cdc.gov/eid/article/30โ€ฆ
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5) The most interesting in our opinion are seroprevalence studies, because they make it possible to measure the number of infected cases while avoiding the pre-symptomatic and asymptomatic debate.
hindawi.com/journals/cjidmโ€ฆ
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6) Here is a recent study done in Cameroun.
journals.plos.org/globalpublicheโ€ฆ
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7) Other studies are interesting because they were carried out over a very long period like here in Australia.
journals.sagepub.com/doi/10.1177/00โ€ฆ
Image
8) More asthmatics with COVID-19 than with INFLUENZA?

We only found 3 studies for influenza, sometimes quite old but which dont seem really significant, with rates between 30 and 50% of asymptomatic. Image
9) When more than one in two people are asymptomatic and therefore difficult to detect, and with a risk of long COVID as many studies show it, we have a circulation of the virus which is uncontrollable and we continue to affirm that it is a real tragedy in terms of public health.
10) Sorry for the typo mistake. On the post 8 it is "asymptomatics" and not "asthmatics" ๐Ÿคทโ€โ™‚๏ธ

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More from @ejustin46

Apr 4
๐™‡๐™–๐™—๐™ค๐™ง๐™–๐™ฉ๐™ค๐™ง๐™ฎ-๐™–๐™˜๐™ฆ๐™ช๐™ž๐™ง๐™š๐™™ ๐™ž๐™ฃ๐™›๐™š๐™˜๐™ฉ๐™ž๐™ค๐™ฃ๐™จ ๐™–๐™ฃ๐™™ ๐™ฅ๐™–๐™ฉ๐™๐™ค๐™œ๐™š๐™ฃ ๐™š๐™จ๐™˜๐™–๐™ฅ๐™š๐™จ ๐™ฌ๐™ค๐™ง๐™ก๐™™๐™ฌ๐™ž๐™™๐™š ๐˜ฃ๐˜ฆ๐˜ต๐˜ธ๐˜ฆ๐˜ฆ๐˜ฏ 2000 ๐˜ข๐˜ฏ๐˜ฅ 2021: ๐˜ข ๐˜ด๐˜ค๐˜ฐ๐˜ฑ๐˜ช๐˜ฏ๐˜จ ๐˜ณ๐˜ฆ๐˜ท๐˜ช๐˜ฆ๐˜ธ


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Image
2) The study conducted a scoping review of reports of laboratory-acquired infections (LAIs) and accidental pathogen escapes from laboratory settings (APELS) between 2000-2021.
It identified 94 reports detailing 309 LAI cases caused by 51 different pathogens. Image
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๐—”๐—œ๐—ฅ ๐—ฃ๐—ข๐—Ÿ๐—Ÿ๐—จ๐—ง๐—œ๐—ข๐—ก ๐—ฎ๐—ป๐—ฑ ๐—–๐—ข๐—ฉ๐—œ๐——-19

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sciencedirect.com/science/articlโ€ฆ
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Apr 2
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2) ๐™•๐™ค๐™ค๐™ฃ๐™ค๐™จ๐™š๐™จ ๐™ค๐™› ๐™™๐™ž๐™ซ๐™š๐™ง๐™œ๐™š๐™ฃ๐™ฉ ๐™˜๐™ค๐™ง๐™ค๐™ฃ๐™–๐™ซ๐™ž๐™ง๐™ช๐™จ๐™š๐™จ

Porcine deltacoronavirus (PDCoV) is an emerging coronavirus that can infect humans. While no vaccines currently exist, monoclonal antibodies could be a treatment option. Image
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Read 7 tweets
Apr 1
๐™ˆ๐™ฎ๐™ค๐™˜๐™–๐™ง๐™™๐™ž๐™–๐™ก ๐™„๐™ฃ๐™Ÿ๐™ช๐™ง๐™ฎ ๐™—๐™ฎ ๐˜พ๐™Š๐™‘๐™„๐˜ฟ-19 ๐™„๐™ฃ๐™›๐™š๐™˜๐™ฉ๐™ž๐™ค๐™ฃ


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2) This prospective multicenter study aimed to assess the prevalence of myocardial injury in patients with COVID-19 using cardiac magnetic resonance imaging (CMR). The researchers screened 505 patients with moderate to severe COVID-19 from 7 hospitals in Japan. Of these patients Image
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Apr 1
๐™‡๐™ค๐™ฃ๐™œ-๐™ฉ๐™š๐™ง๐™ข ๐™ง๐™ž๐™จ๐™  ๐™ค๐™› ๐™ฅ๐™จ๐™ฎ๐™˜๐™๐™ž๐™–๐™ฉ๐™ง๐™ž๐™˜ ๐™™๐™ž๐™จ๐™ค๐™ง๐™™๐™š๐™ง ๐™–๐™ฃ๐™™ ๐™ฅ๐™จ๐™ฎ๐™˜๐™๐™ค๐™ฉ๐™ง๐™ค๐™ฅ๐™ž๐™˜ ๐™ฅ๐™ง๐™š๐™จ๐™˜๐™ง๐™ž๐™ฅ๐™ฉ๐™ž๐™ค๐™ฃ, ๐™–๐™›๐™ฉ๐™š๐™ง ๐™Ž๐˜ผ๐™๐™Ž-๐˜พ๐™ค๐™‘-2 ๐™ž๐™ฃ๐™›๐™š๐™˜๐™ฉ๐™ž๐™ค๐™ฃ, ๐™–๐™ข๐™ค๐™ฃ๐™œ ๐™๐™† ๐™œ๐™š๐™ฃ๐™š๐™ง๐™–๐™ก ๐™ฅ๐™ค๐™ฅ๐™ช๐™ก๐™–๐™ฉ๐™ž๐™ค๐™ฃ

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2) The study used data from UK Biobank, a large prospective cohort study, to examine psychiatric outcomes after SARS-CoV-2 infection. Image
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Read 8 tweets
Apr 1
๐™Š๐™ฃ๐™š ๐™ค๐™› ๐™ฉ๐™๐™š ๐™—๐™ž๐™œ๐™œ๐™š๐™จ๐™ฉ ๐™๐™๐˜ผ๐™‚๐™€๐˜ฟ๐™„๐™€๐™Ž ๐™ค๐™› ๐™ฉ๐™๐™ž๐™จ ๐™‹๐˜ผ๐™‰๐˜ฟ๐™€๐™ˆ๐™„๐˜พ ๐™ž๐™จ ๐™ฅ๐™–๐™ง๐™–๐™™๐™ค๐™ญ๐™ž๐™˜๐™–๐™ก๐™ก๐™ฎ ๐™ฉ๐™๐™š ๐˜ผ๐™Ž๐™”๐™ˆ๐™‹๐™๐™Š๐™ˆ๐˜ผ๐™๐™„๐˜พ๐™Ž

It would be so much "simpler" if all those infected were symptomatic. We would know who is sick, and we could treat them. Image
2) By allowing a very strong circulation of the undetected virus, which we know causes even in asymptomatic people a weakening of the immune system and long COVID, SARS-COV-2 has "signed a pact with the devil"
3) This is the stupidity of the herd immunity theory, which forgets that there is no immunity against SARS-COV-2, and that one can be contagious without symptoms, and cause serious symptoms in other individuals.

Where is in this graph "not immunised, not sick, BUT contagious" ? Image
Read 15 tweets

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