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Apr 9 1 tweets 1 min read Read on X
Vitamin B1 is a PED.

Megadosing this nutrient (as TTFD) in animals:

• QUADRUPLED endurance
• Enhances cellular ATP content
• Lowered lactic acid
• Improved glycogen (stored sugar)

>1 gram human dose, wouldn't go that high, but the effect is potent even at lower doses.Image

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More from @Outdoctrination

May 15
These things suck.

Let’s tackle some strategies to get rid of EYE FLOATERS (and optimize your vision):
TOP: Eyes of someone with bad eye floaters

BOTTOM: 6 months after taking a supplement of:

⬩125 mg l-lysine
⬩40 mg vitamin C
⬩26.3 mg grape vine extract
⬩5 mg zinc
⬩100 mg sour orange extract

(called VitroCap N)Image
People taking this supplement had a near 50% improvement in subjective visual discomfort from eye floaters

And they also had a measurable decrease (~50%) in the amount of their eyes that were gummed up by floaters compared to those that didn’t take it.Image
Read 25 tweets
May 13
PREGNENOLONE: A fountain of youth

1. Pregnenolone lowers stress - restores youthful appearance

As we age, we:

☞ Put on more fat
☞ Lose muscle
☞ Produce less energy
☞ Do so in a more stressful manner

The primary stress hormone, cortisol, actually predicts your perceived age.

In other words, the lower your stress, the younger you appear to other people, and the younger you likely are biologically!

Stress directly promotes the breakdown of

☞ Skin
☞ Hair
☞ Muscle

while promoting the creation of fat mass.

Pregnenolone INHIBITS the release of CRH, the hypothalamic precursor of cortisol.

Prengnolone’s ability to inhibit the release of CRH/CRF is unique, targeting stress at the most basic biological root cause.

Pregnenolone also functionally inhibits the receptor for cortisol.

The "pregnenolone facelift" phenomenon is real.

The production of pregnenolone and its metabolites like DHEA, declines in aging, while the production of stress steroids like cortisol continue to rise.

The ratio of DHEA/Cortisol is one of the best predictors of disease and mortality, and declines with aging.

Pregnenolone also gets metabolized in large quantities to progesterone, which also inhibits CRH release and is a direct antagonist on the cortisol receptors.

Progesterone has GABAnergic effects, which is the key relaxing signaling molecule in the body.

Another compound which pregnenolone largely gets converted into is allopregnanolone, our body’s primary endogenous GABAnergic steroid.

2. Pregnenolone is anti-inflammatory

CRH, independently of cortisol production, also contributes to stress, disease and aging, by initiating inflammation.

Inflammation is uniformly seen in all chronic diseases and in the aging process, as it

☞ Breaks down our tissue
☞ Dampens energy production
☞ Generally makes us feel crappy

Pregnenolone actually degrades the toll like receptors (TLRs) that initiate inflammation in conditions from Alzheimer's disease to IBS.

3. Pregnenolone increases energy

As we age, our mitochondria become:

☞ More susceptible to damage
☞ More fragmented
☞ Smaller
☞ Less effective at producing energy,
☞ More prone to generate free radicals

but pregnenolone allows them to

☞ Produce more energy,
☞ Produce less with oxidative stress
☞ Undergo fusion, when mitochondria come together and become more robust.

The pro-energy effects of pregnenolone have been observed for nearly a century.

Some early studies showed that workers, especially those under stress, subjectively felt better when doing so with pregnenolone.

This anti-fatigue effect was also demonstrated in arthritic patients.

100-500 mg of pregnenolone taken orally has consistently shown an anti-fatigue, cognitive enhancing and anti-stress/anxiety effect.

I'll link the pregnenolone we use ourselves and with clients below.

Perhaps the most noteworthy testimonial:

" 'I didn't have my usual summer recovery from "winter sickness,' during a two week trip I felt perfectly well, but except for that short time I kept getting sicker and sicker (with inflammation of arteries, dental abscesses, asthma, migraines, and colitis).

Lying in bed one day trying to understand what had happened during that two week trip, I remembered that I had used the vitamin E containing a residue of pregnenolone on the trip, but used pure vitamin E after I got home.

I immediately got out of bed and took a pinch of pregnenolone. In about an hour, all of my
symptoms had stopped, and for over a week I was healthy and energetic.

But then I got sick again, and was so distracted by the pain that it was several days before I remembered the pregnenolone. Another pinch had the same dramatic sudden effect.

Since then I have taken some almost every day."

- Ray Peat

Look at his transformation!Image
They are back in stock! healthnatura.com/pregnenolone-2…
Read 6 tweets
May 11
Vitamin K2: the most underappreciated nutrient

One of my absolute favorite supplements. Why?

Vitamin K2 is actually used as a part of mitochondrial metabolism, in a similar manner to that of Coenzyme Q 10.

Due to this it has an incredible range of beneficial properties:

1. COGNITIVE

Vitamin K2 can treat depression.

MK-7 improved depression at just 90 ug/day, a pretty puny dose, through its:

◦ Energy producing, pro mitochondria
◦ Hormone mediating
◦ Anxiolytic

properties.

Vitamin K2 reverses aging in the brain.

Giving K2 (MK-7) to old animals (5 mg / kg human equivalent) improved:

• Anxiety
• Depression
• Memory

by:

• Improving dopamine output
• Reducing inflammation
• Reducing oxidative stress

In animals subject to stress, it:

‣ Decreased signs of anxiety
‣ Decreased signs of depression

Vitamin K2 exerts neuroprotective effects, as it:

- Enhances neuron mitochondrial function
- Prevents death of dopamine producing neurons

2. ANDROGENIC

Vitamin K2 boosts testosterone production.

By enhancing key steroidogenic enzymes in the testes, MK-4 enhances the gonadal response to stimulation.

3. INSULIN SENSITIZING

Due to its pro mitochondrial properties, K2 was able to restore blood sugar in response to a bad diet in animals.

Vitamin K2 megadosing improves insulin sensitivity in humans.

90 mg of K2 daily (MK-4) reduced insulin secretion to maintain blood sugar.

Low dose vitamin K2 reverses fatty liver disease in animals.

Less than 1 mg human equivalent dose MK-7 daily completely protects and regenerates the liver.

High liver enzymes (ALT, AST, GGT, ALP) are the red flag - would consider supplementation.

4. GUT HEALTH

One of my personal favorites for the gut, working on fundamental pathways to enhance digestion.

K2 is

⬨ Antibacterial
⬨ Anti-inflammatory
⬨ Key for intestinal cell function

I use anywhere from 20-40 mg of MK-4 situationally and have had success with clients in this range.

Animals given Crohn's disease, when also given Vitamin K2 (MK-4) (2.5 mg/kg human equivalent):

• Repaired gut damage and barrier
• Lowered inflammation
• Increased mucus production

comparable to the leading drug for IBD (ASA).

5. DENTAL HEALTH

Dental problems? Your vitamin K2 is probably low.

K2 status is inversely related to:

⬩Severity of gum inflammation
⬩Plaque index
⬩Bleeding
⬩Depth of tooth pocket

Literally every dental clinical parameter.

K2 is a cornerstone of calcium metabolism, allowing for minerals to accumulate in bones and teeth properly and regenerate.

This is a huge reason why Weston Price never saw tooth decay in societies focusing on fat soluble vitamins!

MK-4 is found in cheese, liver, and egg yolks predominantly, while MK-7 is mainly in fermented foods (natto)

Both can be massively beneficial to supplement in doses higher than what you can get from food, and I use it all the time personally and with clients.Image
Read 5 tweets
Apr 7
Acne, wrinkles and even eczema: the answer is where you least expect it.

How SUNLIGHT can fix nearly every skin problem:Image
ACNE: DRASTICALLY improved by blue light therapy, a major component of daytime sunlight.

Just 15 minutes, twice weekly.Image
WRINKLES: reversed with the power of red and near infrared light.

The sun gives off tons of these types of light.

Again, just 15 minutes a day a few times weekly.Image
Read 17 tweets
Apr 3
Crushing anxiety and stress, raising IQ and even preventing cancer?

Just some of the things that the incredible PROGESTERONE can do (even for guys).

Here’s how:Image
Progesterone prevents cancer.

Natural progesterone decreases risk by over 20%.

Breast and colon cancer risk significantly drop.Image
Progesterone increases intelligence.

Giving several hundred mg progesterone to pregnant mothers increased their children’s intelligence across the board.

They started walking earlier, and even had better craft skills.Image
Read 17 tweets
Apr 3
Glowing skin, silky smooth digestion and thinking in 4K.

This is what is possible when your body isn’t burdened with TOXINS.

The most critical nutrients and methods for detoxification:Image
MOLYBDENUM: a nutrient you’ve never heard of, but is critical for detoxification.

Molybdenum helps convert the toxic sulfite into sulfate.

We NEED sulfate for detoxification.

Molybdenum cofactor deficiency = rapid brain damage

Best food sources: beef liver, pasta, rice.Image
GLYCINE: critical for detoxification.

⬩Drives glutathione synthesis
⬩Directly binds to toxins for excretion
⬩Great for liver health (master detox organ)

Low glycine levels = higher risk of heart disease.

Foods: bone broth, chewy steaks, whole shellfish, gelatin, collagen.Image
Read 24 tweets

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