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Dalton (Analyze & Optimize) Profile picture
@Outdoctrination
Apr 9, 2024 • 1 tweets • 1 min read • Read on X
Vitamin B1 is a PED.

Megadosing this nutrient (as TTFD) in animals:

• QUADRUPLED endurance
• Enhances cellular ATP content
• Lowered lactic acid
• Improved glycogen (stored sugar)

>1 gram human dose, wouldn't go that high, but the effect is potent even at lower doses.Image

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More from @Outdoctrination

Dalton (Analyze & Optimize) Profile picture
Feb 5
Why you SHOULDN'T be hysterical about vitamin C causing kidney stones, and what to do to prevent them (🧵1/10):Image
The idea that vitamin C supplementation can cause kidney stones is not completely baseless, but it does lack context.

Ascorbic acid, or vitamin C, can get metabolized in our cells to create oxalate.

Oxalate is what binds to calcium to form kidney stones in most people.

Seems pretty straightforward, BUT...Image
Ascorbic acid mainly gets converted to oxalate under conditions of high oxidative stress.

That is when ascorbic acid (AA) turns into dehydroascorbate (DHA).

But we have glutathione to help regenerate ascorbic acid from dehydroascorbate.

This depends on your entire antioxidant network.Image
Read 12 tweets
Dalton (Analyze & Optimize) Profile picture
Feb 4
FLUORIDE: The toxin in your water that destroys thyroid function.

Here's how, and what to do about it.

(🧵1/14)Image
Image
In 2024 a massive review of studies was done on the effects of fluoride exposure and markers of thyroid health.

The higher the fluoride concentration in:

◈ Drinking water
◈ Urine
◈ Serum

the higher the TSH level was - a marker of primary hypothyroidism.

TSH rises when the thyroid gland does not respond to stimulation.Image
More importantly, this study showed a marked decrease in thyroid hormones from higher water fluoride concentrations.

The active T3 thyroid hormone and the precursor thyroid hormone T4 both drop off with higher water fluoride concentrations. Image
Read 16 tweets
Dalton (Analyze & Optimize) Profile picture
Feb 3
A recent study showed that vitamin K2 was protective against every single metric of dental health measured.

(🧵1/8)Image
This paper came out in 2023 in Healthcare.

They aim was simple - look at vitamin K2 levels in relation to dental health.

They did this by looking at carboxylated osteocalcin levels - which reflects whole body K2 status. Image
Specifically they were looking at a condition called periodontitis.

This is essentially dental inflammation, especially in the gums but also impacting the teeth themselves.

These are the stages, with gingivitis being early and stage 5 being very severe. Image
Read 11 tweets
Dalton (Analyze & Optimize) Profile picture
Feb 1
An astounding study shows that 1/2 a teaspoon of baking soda lowered inflammation within hours.

(🧵1/9)Image
Study was published in 2018 in The Journal of Immunology.

Some experiment were done in rodents including baking soda in the water.

Some groups had their vagus nerves cut.

Other animals had a surgery to disturb the spleen.

Both surgeries were done to see if these tissues mediated the effect of baking soda.

Then, the human studies were done comparing drinking 2g of baking soda dissolved in water vs 2g of salt.

(2/9)Image
Animals consuming baking soda in the water showed decreased inflammation in several areas.

In both the kidneys and in the spleen, they had decreased inflammatory M1 macrophages, one of the primary immune cells.

Baking soda increased M2 macrophages, signifying that the macrophages turned into a more anti-inflammatory phenotype.

They also had:

↑IL-10 in the kidney (anti-inflammatory cytokine)
↑FOXP3 cells in blood + kidney (Treg cells, anti-inflammatory immune cells)
↓CD4 T Cells (inflammatory)
↓CD44 T cells (inflammatory)
↓TNFα macrophages (primary inflammatory mediator)

(3/9)Image
Read 10 tweets
Dalton (Analyze & Optimize) Profile picture
Jan 31
MOLD: A silent cause behind your health issues.

Fortunately, there are several tools we can use to directly bind and eliminate their toxins.

Here's 5 of the most useful (🧵1/7):

(IMPORTANT: READ UNTIL END)Image
#1 Humic acids

These are materials formed from organic matter decomposition, and it's found in shilajit.

This study showed that including them in the diet could both bind and prevent the liver cancer from a common food mycotoxin, aflotoxin B1.

Typically dosing starts at 100 mg.Image
#2 Bentonite

This is a clay substance that is highly efficient at binding to mycotoxins.

This paper showed ~50% reductions in key mycotoxins along with reduced organ damage.

Doses are higher, 500+ mg. Image
Image
Read 9 tweets
Dalton (Analyze & Optimize) Profile picture
Jan 30
5 research backed tools to lower cortisol:

#1 GABA

GABA completely stopped cortisol in clinical trial.

25-50 mg orally - it in response to physiological stress, improving:

⊙ Fatigue
⊙ Concentration
⊙ Physical discomfort

(🧵1/9)Image
GABA can suppress cortisol by its action in the brain.

The hypothalamus produces CRH ➞ pituitary to produce ACTH ➞ adrenals to produce cortisol.

GABA input to the hypothalamus calms these neurons, preventing CRH release and cortisol production.

(2/9) Image
Image
#2 Grounding

6 weeks of grounding completely normalized the cortisol pattern throughout the day in this trial,

& improved sleep.

The difference is dramatic in my experience (+ with clients).

(3/9) Image
Read 11 tweets

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