Jesse Singal Profile picture
Apr 15 4 tweets 2 min read Read on X
1/ The Cass Review explains, in detail, why we need to trust systematic reviews over both doctors' anecdotal evidence and low-quality standards published by professional associations. The CBC responds by publishing an article that cites professional associations and is dominated by doctors' anecdotal accounts.

Science journalism seems screwed at the moment.

cbc.ca/news/health/pu…
2/ This might be the worst bit:

"Surveys and interviews are considered low-quality evidence in medicine, said [Pediatrician Dr. Tehseen Ladha], but that might be misleading to the general public. 'Many people would see low-quality evidence and think well, that means this could harm our children. But that's not what it means.' "

That's... exactly what low-quality evidence for a major intervention means. It means we don't know if the intervention offers a net benefit, because the true effects might differ significantly from what the studies in question present.Image
3/ Stuff like this isn't just the normal incompetence and sloppiness that plagues this subject. It is critically dangerous science miscommunication disseminated by the most important outlet in Canada. It's absolutely inexcusable and has to stop.
4/ Just wanna be clear about this: Let's say "low-quality" studies seem to tell us that an intervention improves things .5 points on a 10-point scale for patients. Doesn't matter what you're measuring. What that means, to oversimplify, is that we don't have confidence the intervention in question will actually have that effect on people. It could be higher, but it could be lower, changing the direction of the sign entirely.

I'd argue more structural forces within science publishing nudge us toward overstating rather than understating benefits, but whether or not you agree, the idea of this intervention being harmful is *absolutely* on the table in this sort of situation. The CBC is spreading rank BS here -- it's so, so bad. I don't understand how this keeps happening.

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More from @jessesingal

Apr 11
1/ Sam Seder just found out about the Cass Report yesterday and he is VERY concerned
2/ Should address one substantive point here. The caller says the Cass Review threatens access to hormones/surgery for any trans person under 25. This is NOT true. It's a viral rumor that popped up right after the report came out. I think the source is Erin Reed.
3/ Reed appears to be one of the most viral sources of misinformation about youth gender medicine within trans activism. In this case, she badly misread a part of the Cass Review and seeded her audience with the false 25 claim. Image
Read 5 tweets
Mar 19
wait what Image
2/ "Heyyyy I'm ridin' heah! I love da camoonity of my fellow ridahs! Fugheddaboutiiiiiiiiiiiiiiiiiiiiiiiiiiiit"
3/ I asked 20 of my fellow New Yorkers what they love most about the subway

-15 ignored me
-2 tazed me
-1 vomited on me
-2 replied with some variation of "fuck off"
Read 4 tweets
Mar 8
Strange evening. The ACLU of Missouri subpoenaed Jamie Reed, demanding (among other stuff) all her communications w/me. I emailed them saying (politely) wtf, you're the ACLU. Got a call from a lawyer there saying it was a mistake -- "It's a big team." Okay.
Image
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2/ Here's the supoena, not current since they're removing the "Jessie Singal" bit. Also in on the effort was Lambda Legal. Weird this was a mistake given that it's the second thing listed and tons of eyes must have been on this before it was filed. 🤷‍♂️

drive.google.com/file/d/1TugDqb…
3/ It's literally all just Harry Potter fanfic anyway but still alarming
Read 6 tweets
Feb 3
Who would have thought a program called Woke Kindergarten wouldn't have succeeded where a century's worth of other efforts to end educational inequality have failed? Truly surprising stuff. Maybe if they got more funding...?
Image
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2/ Lemme take a crack at this: "This exceptionally stupid idea that any questions about any DEI programming constitute an attack on 'anti-racism' itself has given cover to grifters and opportunists at the expense of poor kids." Not true but a familiar-sounding argument.
3/ I wonder which aspect of this program fell short given how scientific and rooted in cutting-edge pedagogy it seems. The only injustice here is that Woke Kindergarten was not allowed to take over the entire SF education system. Image
Read 8 tweets
Sep 3, 2023
1/ Maybe I'll newsletter about it but maaaaan is this a frustrating article. There's nothing wrong with pointing out how crazy Kiwi Farms can get, but this is so factually challenged and tilts so heavily toward a certain whitewashed activist account...

washingtonpost.com/technology/202…
2/No one familiar with this stuff believes Kiwi Farms went after Liz Fong-Jones because she "donated to a transgender nonprofit"!!! This is ridiculous. The conflict has to do with LFJ's perceived closeness to the scammer(s) (I forget if it was one or both) who ran Trans Lifeline Image
3/ at a time when it was completely dysfunctional. We now know, *because the new leadership at TLL said so explicitly in a financial document,* that Kiwi Farms was correct about said scammers -- they bilked this charity out of hundreds of thousands of dollars. Furthermore, KF and
Read 8 tweets
Aug 20, 2023
Are any health/science reporters at major outlets that cover the youth gender medicine debate going to reach out to the authors of this viral meta-analysis to ask what's going on? Anyone? Overstating sample size by thousands isn't a big enough red flag for you?
2/ When you support trans people so much you accidentally invent thousands of them to introduce into a meta-analysis, swelling your sample size by 42%.

(Original study sample size was 7,928. We now know that about 3,336 of those individuals do not exist. Very Serious Science.)
3/ I'd be curious to hear from @siminevazire and other openness/reproducibility experts if they can come up with a single other instance in which a meta-analysis was published only for it turn out that 42% of its sample didn't exist. Is this unprecedented?
Read 4 tweets

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