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Dr Elisa Perego Profile picture
@elisaperego78
Apr 16 • 13 tweets • 5 min read • Read on X
We're in the most devastating pandemic in one century, with an estimated 20—30 million dead; an estimated 400 millions to have experienced #LongCovid; immune dysfunction; and a surge in other infectious diseases. It's not over. This is a key reason why people are so often sick
Bibliography as usual. Excess mortality from Covid at ~30 million dead. Additional estimates in such range (20 to 30 millions) by WHO, and others (a review in Perego 2023b, attached)



wsws.org/en/articles/20…
osf.io/preprints/soca…
Estimated cases of #LongCovid at 65 to hundreds of millions by Davis et al 2023; Altmann et al. 2023; Chen et al. 2022; WHO 2023. A review in Perego 2023b, attached

osf.io/preprints/soca…
The evidence of immune dysfunction (with various presentation and broadly speaking) following SARS-CoV-2 infection is extensive. It's well documented in both the literature and lived experience of patients. It was already noted in 2020 (e.g. lymphopenia)

jintensivecare.biomedcentral.com/articles/10.11…
Immune dysfunction is also widely described beyond the acute phase of Covid e.g. (a note: even transient immune dysfunction would and must be alarming in the context of ongoing reinfections)

.nature.com/articles/s4142…
As we know too well, SARS-CoV-2 has a great ability to reinfect, even the same individual within a short period of time. Given the lack of safety measures (e.g. clean air and masks) in many contexts, reinfections are, by no, means rare.

link.springer.com/article/10.100…
Previous SARS-CoV-2 infection and #LongCovid could be linked to worse outcomes with later infection with other viruses, an area of research we really need to explore further



doi.org/10.1136%2Ffmch…
(The cases above are about RSV apparently being more serious post Covid, and an influenza A infection with complications in a patient with persistent symptoms in #LongCovid). There are other cases of course

doi.org/10.1136%2Ffmch…
We shouldn't discount, in addition, cases of coinfections of SARS-CoV-2 with other pathogens, which have been reported in studies to increasing the risk from Covid

mdpi.com/1648-9144/59/7…
The resurgence of other diseases such as measles is unfortunately underway; this is in addition to the introduction or reintroduction of diseases, such as dengue, mpox, West Nile fever and others, in areas where such diseases were absent or rare

All of this, in addition to the damage inflicted to healthcare systems by Covid and financial cuts, contributes to explain the increase in sickness many are seeing and reporting from multiple countries
WHO on hundreds of millions people facing Long Covid and in need of medical care

WHO on at least 20 million people dying from Covid, data from 2023

icirnigeria.org/who-raises-glo…

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More from @elisaperego78

Dr Elisa Perego Profile picture
Apr 17
A kind reminder to policymakers etc. making promises now, that you have *already* let Long Covid patients down. You're too little, too late. Long Covid was openly recognised by WHO in August 2020. People have died since. You might even have participated in "let it rip" dynamics
The Covid pandemic is one of the greatest health disasters in modern history. A preventable disaster, I'd suggest. An estimated 20-30 millions have died. An estimated 400 millions have experienced #LongCovid. We knew how dangerous SARS-CoV-2 was in 2020

osf.io/preprints/soca…
Despite extensive knowledge on the dangers of SARS-CoV-2, including Long Covid, we had in 2020, this dangerous SARS virus was left to rip. There was no appropriate enough answer to the Long Covid crisis. Of course, research is extensive, but access to diagnostics and care, isn't
Read 5 tweets
Dr Elisa Perego Profile picture
Apr 17
A kind reminder that the persistence of SARS-CoV-2 has been posited and increasingly demonstrated (at least in a number of subjects) since 2020—1. Long Covid patients and patient-researchers have been at the forefront of this. Policymakers are late.
While we need to fully elucidate the impact of SARS-CoV-2 persistence (with different manifestations) on human health (especially in the long-term), the precautionary principle should have been in place, including in view of data emerging since 2020, and data on SARS-CoV-1 (SARS)
Policymakers were alerted early about the possibility of viral persistence; and research on the topic has only been accruing over time. They should have acted much faster, both in terms of preventing new infections; and planning how to treat patients when persistence is proven
Read 7 tweets
Dr Elisa Perego Profile picture
Apr 13
Usual reminder that "living with Covid" policies need the erasure and minimization of #LongCovid to be effective. People wouldn't accept themselves and their children to be be mass infected with a SARS virus if they were fully aware of the risks
People with a glaring conflict of interest, such as minimizing of the pandemic threat, have all the interests in minimizing/erasing #LongCovid, as they could be held accountable for the damage their policies caused to the global population, including children
A glaring case in point is Australia's Queensland CHO Gerrard, who deemed infection with SARS-CoV-2 "necessary" in late 2021 (with devastating consequences) and recently claimed we should stop using the term #LongCovid altogether. Conflict of interest

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Read 8 tweets
Dr Elisa Perego Profile picture
Apr 7
The desperate fight by policymakers like Queensland's CHO to drop the term #LongCovid is evidence of the term's power and efficacy, and of our activism. They wouldn't need to fight so hard and try to mobilize the press otherwise. I'll keep using the patient made term Long Covid
Policymakers and pundits who have been involved in minimizing the dangers of SARS-CoV-2 infection, obviously, have a great interest in dropping a term, Long Covid, which has been so useful in drawing attention to the long-term damage from this infection

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We were right in 2020. We are right now. They have been wrong across the pandemic. They're wrong now. SARS-CoV-2 infection is far from benign. Covid is far from being a two-week disease, harmless in the 'young and healthy", "mild" and harmless in children
Read 5 tweets
Dr Elisa Perego Profile picture
Apr 6
No. #LongCovid is a multi-system, heterogeneous disease entity which is proven to be disabling, life-threatening, even fatal in a subset. "Light rehabilitation" won't treat it. Please do better, especially if you're a public figure with degrees in medicine/adjacent fields
Choosing to highlight a flawed, small-scale study on #LongCovid from a big platform, rather than the thousands of research papers that document severe pathology down to the cellular level, is wrong. Policymakers and medical professionals must do better.
People with Long Covid deserve better, including because so many are victims of erroneous pandemic policies. Policies brought on us by the same policymakers who are now trying to minimize the severity of the disease, including it's potentially fatal nature (scientifically proven)
Read 8 tweets
Dr Elisa Perego Profile picture
Apr 5
It's not surprising, in my opinion, that so many attempts at erasing #LongCovid, or minimizing the grassroots LC movement, come from Australian policymakers and academics. Australia was a zero Covid country that was pushed into mass infection, with devastating consequences
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It's obvious, thus, that Australia's establishment is particularly concerned about the Covid death toll and LC being a key topic of scrutiny: Australia had a choice: life and health. The wrong choice was made. Critically, was this choice taken freely and consciously by citizens?
Or were Australians led to believe letting SARS-CoV-2 spread would be with little real-life consequences? Looking at discourses around dropping zero Covid are of interest: e.g. legitimate concerns about being infected with a SARS virus are depicted as "anxiety" in the press Image
Read 8 tweets

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