COVID’S EFFECT ON THE IMMUNE SYSTEM

🔥 This is an excellent series of graphics from @YaleSPH explaining what we do (and don’t) know about Covid’s effect on the immune system.

Much of this is informed by the work of Dr. Akiko Iwasaki (@VirusesImmunity).

🧵

H/t @fitterhappierAJ Image
This fantastic series of graphics have come from a Facebook post by Yale School of Public Health at the link below:

facebook.com/10006428075591…
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LASTING IMPACT

▪️Growing research shows infection with SARS-CoV-2 can create lasting differences in some people's immune systems. Image
THIS LOOKS LIKE...

1. Altered immune system cells which are more inflammatory.

2. Viral reservoirs and fragments which can set off a continuing immune response.

3. Immune dysregulation & chronic inflammation

4. Triggered autoimmune conditions, blood clots & latent viruses Image
▪️5-20% of people develop lingering symptoms or new health conditions after infection, called Long COVID.

▪️As of the CDC's latest count in March 2024, 30% of all American adults who've had COVID have experienced Long COVID. Image
▪️The more COVID-19 vaccine doses you get, the lower the risk of Long COVID.

▪️The more reinfections you have, the higher the risk. Image
172% INCREASED RISK

▪️The risk of developing an autoimmune disease rose by up to 172% after infection, per a study following people from 2020 to 2022.

▪️Up-to-date COVID-19 vaccination can reduce the likelihood of developing an autoimmune condition after infection. Image
OTHER ILLNESSES

▪️SARS-CoV-2 can also activate other viruses that have been lying dormant, like Epstein-Barr and herpes viruses.

▪️Studies have found kids with prior COVID-19 infections had a greater risk of RSV infections. Image
49% OF COVID INFECTIONS ARE ASYMPTOMATIC…

…which means you may not know if you are actually sick.

This is why it's important to take a multilayered approach to protect yourselves & others:

▪️Masks
▪️HEPA air filtration
▪️Good ventilation
▪️Up-to-date vax
▪️Rapid tests Image
WHAT WE DON'T KNOW

1. The long-term impact on other illnesses

2. Why some people's conditions persist

3. What diagnostics and therapies can help restore the immune system Image
Link to Facebook post by Yale School of Public Health:



You can also find a link to all the graphics & source citations from the graphics in pdf format below (kindly compiled by Jean Du Pays on Facebook) ⬇️

facebook.com/10006428075591…
pdflink.to/yale-covid-19-…


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More from @_CatintheHat

Oct 13
Why do schools need to tackle poor VENTILATION in classrooms?

Because nationwide monitoring of UK classrooms shows that ventilation drops to appallingly low levels when outdoor temperatures drop & windows are closed.

Poor ventilation means airborne viruses spread like wildfire. Image
And when those airborne viruses spread like wildfire, guess what happens to pupil & teacher absence rates?

Unsurprisingly, they sky rocket! 🚀

Here’s what happened to absence rates in the 2023/24 & 2024/25 autumn terms (vs the pre-pandemic average shown by the dotted line) ⬇️ Image
Now look what’s happening to illness in 15-24 year olds right now… 👀

Covid rates have been steadily rising and are now at the highest point in over a year for this age-group.

Meanwhile, flu has seen a dramatic rise about a month earlier than usual.

(Chart from @1goodtern) Image
Read 6 tweets
Oct 13
The DfE have published guidance on reducing the spread of illness this Winter.

Much of it focusses on things like handwashing & catching sneezes which WON’T stop airborne illnesses spreading.

BUT I’m pleased to see a whole section on VENTILATION, CO2 MONITORING & AIR FILTERS. Image
Link to this newly published guidance can be found here:

educationhub.blog.gov.uk/2025/10/reduci…
The joint unions have also just released newly updated guidance:

“GOOD VENTILATION IN SCHOOLS & COLLEGES AND HOW TO ACHIEVE IT!”

This excellent guide sets out 5 simple steps which schools should be taking to monitor & improve ventilation in classrooms.

neu.org.uk/sites/default/… x.com/neunion/status…Image
Read 6 tweets
May 22
“LONG COVID IS FUELLING A MENTAL HEALTH CRISIS IN CHILDREN”

🚨Nearly 40% of children with Long COVID reported anxiety or depression; half had no prior diagnosis.

🚨Mental health impact was comparable to that of serious chronic illnesses like cancer.

neurosciencenews.com/long-covid-chi…Image
Meanwhile, more than 500 children a day in England are being referred to NHS mental health services for anxiety, more than DOUBLE the pre-pandemic rate…

…and yet, the impact of repeated COVID infections on children is never even considered as a contributing factor. Image
There are so many studies about the detrimental impact that Covid has on the brain…

…how the brain inflammation can trigger neurological symptoms such as depression & anxiety.

I don’t understand why this is just being ignored by the mainstream media.

health.harvard.edu/mind-and-mood/…Image
Read 4 tweets
May 15
LONG COVID IN UNIVERSITY STUDENTS

🚨40% of the undergrad students reported brain fog due to COVID-19.

🚨37 % of the undergraduates exhibited impaired cognition up to 17 months post-infection.

🚨Brain fog appeared to affect the distinct prefrontal haemodynamic patterns. Image
This study was conducted by scientists at the University of Otago (NZ) who were looking to investigate the cognitive effects of COVID infection in a population highly representative of young adults: undergraduate university students.

Link to full study:
sciencedirect.com/science/articl…Image
A summary article about this worrying study can also be found here:

“New neuroscience research shows COVID-19 leaves mark on young adult brains” (Feb 2025)

psypost.org/new-neuroscien…Image
Read 4 tweets
Mar 15
Today, in honour of #LongCovidAwarenessDay, I’m sharing a series of short videos from Dr Rae Duncan (@Sunny_Rae1) about the ongoing impact of Long Covid.

1. WHAT IS LONG COVID?

Long Covid is a multi-systemic inflammatory condition that can affect almost every organ of the body.
2. WHAT ARE THE PRINCIPAL MECHANISMS & MANIFESTATIONS OF LONG COVID?

Dr Rae Duncan explains some of the key manifestations of Long Covid, including:

▪️immune-mediated issues

▪️abnormalities of the autonomic nervous system (the nerves which control things like our heart rate).
3. WHAT ARE THE MAIN SYMPTOMS OF LONG COVID?

Dr Rae Duncan discusses some of the most prevalent symptoms of Long Covid, such as fatigue and post-exertional malaise.

There are over 200 recognised symptoms of Long Covid though, so each patient may experience different symptoms.
Read 11 tweets
Feb 18
⚠️ IPC GUIDANCE

Newly-appointed Health Minister @AshleyDalton_MP has just responded to a question from MP @_Chris_Coghlan.

Chris asks when the NHS IPC manual will be updated to reflect the latest science on AIRBORNE transmission.

Let’s take a closer look at Ashley’s reply… Image
The key bit is highlighted in yellow here:

“Should new evidence emerge that warrants updates, the guidance will be reviewed & revised accordingly by NHS England & UKHSA to ensure the highest standards of infection prevention & control are maintained across healthcare settings.” Image
Well @AshleyDalton_MP, new evidence HAS emerged.

It’s not even new news as we’ve known about it since 2020!

There’s not a single credible scientist who still denies that Covid is transmitted via the AIRBORNE route.

Please listen to independent expert witness Prof Beggs here ⬇️
Read 27 tweets

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