Cat in the Hat 🐈‍⬛ 🎩 🇬🇧 Profile picture
Apr 22 11 tweets 5 min read Read on X
COVID’S EFFECT ON THE IMMUNE SYSTEM

🔥 This is an excellent series of graphics from @YaleSPH explaining what we do (and don’t) know about Covid’s effect on the immune system.

Much of this is informed by the work of Dr. Akiko Iwasaki (@VirusesImmunity).

🧵

H/t @fitterhappierAJ Image
This fantastic series of graphics have come from a Facebook post by Yale School of Public Health at the link below:

facebook.com/10006428075591…
Image
LASTING IMPACT

▪️Growing research shows infection with SARS-CoV-2 can create lasting differences in some people's immune systems. Image
THIS LOOKS LIKE...

1. Altered immune system cells which are more inflammatory.

2. Viral reservoirs and fragments which can set off a continuing immune response.

3. Immune dysregulation & chronic inflammation

4. Triggered autoimmune conditions, blood clots & latent viruses Image
▪️5-20% of people develop lingering symptoms or new health conditions after infection, called Long COVID.

▪️As of the CDC's latest count in March 2024, 30% of all American adults who've had COVID have experienced Long COVID. Image
▪️The more COVID-19 vaccine doses you get, the lower the risk of Long COVID.

▪️The more reinfections you have, the higher the risk. Image
172% INCREASED RISK

▪️The risk of developing an autoimmune disease rose by up to 172% after infection, per a study following people from 2020 to 2022.

▪️Up-to-date COVID-19 vaccination can reduce the likelihood of developing an autoimmune condition after infection. Image
OTHER ILLNESSES

▪️SARS-CoV-2 can also activate other viruses that have been lying dormant, like Epstein-Barr and herpes viruses.

▪️Studies have found kids with prior COVID-19 infections had a greater risk of RSV infections. Image
49% OF COVID INFECTIONS ARE ASYMPTOMATIC…

…which means you may not know if you are actually sick.

This is why it's important to take a multilayered approach to protect yourselves & others:

▪️Masks
▪️HEPA air filtration
▪️Good ventilation
▪️Up-to-date vax
▪️Rapid tests Image
WHAT WE DON'T KNOW

1. The long-term impact on other illnesses

2. Why some people's conditions persist

3. What diagnostics and therapies can help restore the immune system Image
Link to Facebook post by Yale School of Public Health:



You can also find a link to all the graphics & source citations from the graphics in pdf format below (kindly compiled by Jean Du Pays on Facebook) ⬇️

facebook.com/10006428075591…
pdflink.to/yale-covid-19-…


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More from @_CatintheHat

Apr 18
2024 Q1 MORTALITY DATA

Do you want the good news or the bad news?

Ok, let’s start with the GOOD news first:

▪️Overall YTD mortality figures across the whole population remain among the lowest seen.

…but now for the BAD news…

/1
Mortality figures across the whole population are heavily skewed by the older age groups since older people are more likely to die.

Sadly, this is hiding high % increases in the younger age groups, specifically in children aged 0-14 years.

The kids are not ok. 😢

/2 Image
Let’s take a closer look at the data for babies under 1 year old.

As of the end of March 2024, the cumulative standardised mortality rate was already 3.5% higher than the average from 2014-23.

In fact, it’s considerably higher than any other year going back as far as 2012.

/3 Image
Read 6 tweets
Apr 16
Heads up, folks…

It looks like the World Health Organisation are about to come up with alternative terminology for ‘airborne transmission’ in an attempt to save face after denying that Covid was airborne for so long.

I’ve compiled some relevant threads below…

⬇️
Image
Read 9 tweets
Apr 16
PERSISTENT ABSENCE

I’ve been scratching my head trying to figure out where this magical 440,000 figure came from which the DfE are quoting as the reduction in persistent absence…

…because that’s NOT what the official data shows!!

Read on to find out more…

🧵⬇️
Image
According to the latest DfE report, the number of persistently absent pupils decreased from:

▪️22.5% in 2021/22
= 1.64 million pupils

to

▪️21.2% in 2022/23
= 1.57 million pupils

That’s a reduction of just 70,000 pupils, NOT 440,000!

…e-education-statistics.service.gov.uk/find-statistic…
Image
The more important point that is rather glossed over here is that the persistent absence rate of 21.2% in 2022/23 is still nearly DOUBLE the pre-pandemic rate of 10.9%.

Hardly something to be boasting about! Image
Read 31 tweets
Apr 1
There’s nothing more irritating than when you see someone who is so close to joining the dots… but doesn’t quite get there.

I’m never quite sure if it’s intentional or just sheer ignorance… (well actually, I think I can probably guess which it is).

/1


telegraph.co.uk/news/2024/03/2…
Image
Let’s take a look at what she says:

“We must better support our children to attend school safely in any future similar event.”

“We cannot allow our elderly, those in care homes & the vulnerable to be placed at such risk in a future pandemic.”

“Most viruses are airborne.”

/2 Image
Somehow @SuellaBraverman has lined up all the pieces of the jigsaw 🧩 , but still can’t see the bigger picture that is literally staring her in the face!

✅ Yes, another pandemic is coming (as well as the one we’re still in right now).

✅ Yes, we must be better prepared.

/3
Read 19 tweets
Mar 29
🚨 Indoor AIRBORNE Risk Assessment in the context of SARS-CoV-2 from the World Health Organisation (@WHO)

For clean air advocates, this is HUGE!

The WHO are finally saying, loud & proud: COVID IS AIRBORNE.

Let’s take a closer look at the details…🧵

🔗 iris.who.int/handle/10665/3…
Image
Foreword:

“We live immersed in an ocean of air, yet we hardly ever notice its presence. However, without air we would simply not be able to survive.”

“We must reshape & redesign the building environment, while focusing on optimizing indoor ventilation and the air we breathe.” Image
Introduction:

This purpose of this document is to introduce “an innovative method to quantify the risk of SARS-CoV-2 airborne transmission in indoor settings, thereby providing an alternative approach to developing ventilation requirements that lower the risk of infection.” Image
Read 28 tweets
Mar 28
🚨NEW Report presents findings from a review of Long Covid to guide New Zealand’s Public Health response.

Report concludes that “preventative action is urgently needed”.

Let’s dive into the details as the findings are relevant for ALL countries.

🔗

/1 phcc.org.nz/briefing/long-…
Image
Below are some of the key findings of the report:

▪️Changes in health status following SARS-CoV-2 infection are common and can occur at any age.

▪️Symptoms are frequently experienced for months or years and can increase over time.

/2 • Several recent and well-designed cohort studies have reported central estimates ranging from 4 – 14% for ongoing symptoms per infection. • Long Covid includes a full spectrum of severity from hidden effects through mild and transient symptoms to life-changing and life-limiting conditions such as heart attacks and strokes, diabetes, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and neurological disorders. Commonly experienced symptoms such as fatigue and cognitive dysfunction have a high impact on quality of life. • Both SARS-CoV-2 infection and Long Covid are under-counted ...
▪️Future health impacts can be expected in addition to the effects that are already observed.

▪️ Some people who are currently well post-Covid are already expressing biomarkers of risk for cardiovascular disease, neurodegenerative disorders, autoimmune diseases & cancers.

/3 Future health impacts can be expected in addition to the effects that are already known and observed.  • Some people who are currently well post-Covid are already expressing biomarkers of risk for cardiovascular disease, neurodegenerative disorders, a range of autoimmune diseases, and cancers: conditions that typically have latency periods lasting years or decades. • Early-life exposure to infections can have lasting impacts on developing tissues and organ systems. Already, several adverse effects of perinatal Covid-19 exposure have been described. • Pre-pandemic evidence shows the adverse ...
Read 20 tweets

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