2) The paper analyzes aggregated foot traffic data from mobile devices to measure mobility and contact patterns across different place categories (restaurants, retail, etc.) in New York City neighborhoods during the COVID-19 pandemic in 2020.
3) It finds distinct mobility networks and indoor contact patterns (crowdedness, dwell time) vary across place categories and neighborhoods, driven by the local distribution of points of interest and human activities.
4) A behavior-driven epidemic model is developed that incorporates these place-category specific mobility networks and links the force of infection to crowdedness and dwell time using power-law functions.
5) Model fitting suggests force of infection increases sublinearly with crowdedness and dwell time, showing a diminishing returns effect.
When coupled with data assimilation, the model can accurately reproduce neighborhood-level COVID-19 case trends in NYC in 2020 and ...
6) ...generate improved short-term forecasts compared to a baseline model without place-category distinction.
The behavior-driven model captures how social drivers of contagion shaped transmission and ...
7) ...can potentially support outbreak response if adapted for other respiratory diseases spread through similar routes.
Thanks for reading ๐
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"70% to 90% of our CELLS are completely RENEWED in less than 5 YEARS!
So If weโre mostly "New", why are so many still struggling with SARS-CoV-2?
We will tackle this question, which is more complex than it seems, in several posts.
2) First, let's say a few words about cell renewal.
70% to 90% of our cells are renewed over time. This turnover occurs in various cell types, including skin, blood, and immune cells, allowing the body to replace damaged or aged cells. sciencefocus.com/the-human-bodyโฆ
3) For instance, red blood cells have a lifespan of about 120 days, while skin cells regenerate every few weeks.
Even with significant cell renewal, aging persists due to changes in our DNA. sciencefocus.com/the-human-bodyโฆ
2) Co-infection occurs when a person is infected by more than one virus at the same time. This can lead to interesting and sometimes complex interactions between the viruses
3) In one study about SARS-CoV-2, researchers found that when different versions of this virus infect the same person, they can mix their genetic material through a process called recombination. This means that the new version of the virus can have traits from both parent viruses
For more than three years, we have been emphasizing that the envelope protein is an essential component and that we cannot limit our focus to just the spike protein. We are now uncovering its role in long COVID.
3) The Envelope (E) protein of SARS-CoV-2 plays a crucial role for several reasons:
โถ๏ธ Virus Assembly and Release: The E protein is essential for the virus's assembly and budding from infected cells, contributing to its stability and infectivity.
"N''oubliez jamais" (Never forget - Joe Cocker)๐งต
In 2022, COVID-19 was the second leading cause of death globally, with the repercussions of the virus far from over. The lasting impact of the pandemic continues to affect lives around the world.
Recent research may have identified a key factor contributing to long COVID: microscopic clots intertwined with immune system debris in the blood. These unusual structures were found to be nearly 20 times more prevalent ...
2) ...in long COVID patients compared to healthy individuals. The clots, associated with neutrophil extracellular traps (NETs), suggest a potential biological marker for persistent symptoms.
3) These microclots could impede blood flow in small vessels, leading to issues like brain fog, fatigue, and shortness of breath.
Unlocking the Secrets: A Comprehensive Megathread on Key Virus Subtypes of Human and Avian Influenza !"๐งต
First, a quick overview of the different subtypes:
HUMAN INFLUENZA
H1N1 : The 2009 pandemic strain, which continues to circulate
...
2) H3N2: Strain spreading fast actually and causing significant morbidity
H6N1: Notable for potential human impact.
AVIAN INFLUENZA :
H5N1: High pathogenicity, zoonotic concerns.
H3N8: Emerging strain of interest.
H7N9: Associated with human infections, sporadic outbreaks.
3) H5N8: Emerging strain with health implications.
H5N6: Recent cases in birds and humans.
H7N7: Impact on poultry and occasional human cases.
H9N2: Common in birds, history of human infections.