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May 3 โ€ข 5 tweets โ€ข 2 min read โ€ข Read on X
๐™†๐™š๐™ฎ ๐™จ๐™ฉ๐™ช๐™™๐™ฎ :
"๐™‹๐™ค๐™จ๐™ฉ-๐˜พ๐™ค๐™ซ๐™ž๐™™-19 ๐™˜๐™ค๐™ฃ๐™™๐™ž๐™ฉ๐™ž๐™ค๐™ฃ (๐™‡๐™ค๐™ฃ๐™œ ๐˜พ๐™ค๐™ซ๐™ž๐™™) ๐™ž๐™ฃ ๐™˜๐™๐™ž๐™ก๐™™๐™ง๐™š๐™ฃ ๐™–๐™ฃ๐™™ ๐™ฎ๐™ค๐™ช๐™ฃ๐™œ ๐™ฅ๐™š๐™ค๐™ฅ๐™ก๐™š 12 ๐™ข๐™ค๐™ฃ๐™ฉ๐™๐™จ ๐™–๐™›๐™ฉ๐™š๐™ง ๐™ž๐™ฃ๐™›๐™š๐™˜๐™ฉ๐™ž๐™ค๐™ฃ ๐™ค๐™ง ๐™ง๐™š๐™ž๐™ฃ๐™›๐™š๐™˜๐™ฉ๐™ž๐™ค๐™ฃ ๐™ฌ๐™ž๐™ฉ๐™ ๐™Š๐™ข๐™ž๐™˜๐™ง๐™ค๐™ฃ"
. nature.com/articles/s4159โ€ฆ
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2) This study aims to investigate the impact of the Omicron variant on young people 12 months after infection. The study included 345 young people who had their first laboratory-confirmed infection with the Omicron variant and 360 young people who were reinfected ... Image
3) ...with the Omicron variant.
They completed an online questionnaire assessing demographics, symptoms, and their impact at different time points. The most common symptoms reported at 12 months post-testing were tiredness and sleeping difficulties. Image
4) The symptom profiles, severity, and impact were similar in both groups. By 12 months, 17.4% of first-positive cases and 21.9% of reinfected cases fulfilled the research definition of Long Covid. Image
5) Further studies are needed to determine the causality of reported symptoms up to 12 months after SARS-CoV-2 infection.

Thanks for reading ๐Ÿ™ Image

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More from @ejustin46

May 4
๐—›5๐—ก1 ๐—Ÿ๐—”๐—ฆ๐—ง ๐—จ๐—ฃ๐——๐—”๐—ง๐—˜ !
(๐Ÿงต ๐˜—๐˜ˆ๐˜™๐˜› 4)

"๐˜›๐˜ฉ๐˜ฆ ๐˜ข๐˜ท๐˜ช๐˜ข๐˜ฏ ๐˜ข๐˜ฏ๐˜ฅ ๐˜ฉ๐˜ถ๐˜ฎ๐˜ข๐˜ฏ ๐˜ช๐˜ฏ๐˜ง๐˜ญ๐˜ถ๐˜ฆ๐˜ฏ๐˜ป๐˜ข ๐˜ˆ ๐˜ท๐˜ช๐˜ณ๐˜ถ๐˜ด ๐˜ณ๐˜ฆ๐˜ค๐˜ฆ๐˜ฑ๐˜ต๐˜ฐ๐˜ณ๐˜ด ๐˜ด๐˜ช๐˜ข๐˜ญ๐˜ช๐˜ค ๐˜ข๐˜ค๐˜ช๐˜ฅ (๐˜š๐˜ˆ)-ฮฑ2,3 ๐˜ข๐˜ฏ๐˜ฅ ๐˜š๐˜ˆ-ฮฑ2,6 ๐˜ข๐˜ณ๐˜ฆ ๐˜ธ๐˜ช๐˜ฅ๐˜ฆ๐˜ญ๐˜บ ๐˜ฆ๐˜น๐˜ฑ๐˜ณ๐˜ฆ๐˜ด๐˜ด๐˜ฆ๐˜ฅ ๐˜ช๐˜ฏ ๐˜ต๐˜ฉ๐˜ฆ ๐˜ฃ๐˜ฐ๐˜ท๐˜ช๐˜ฏ๐˜ฆ ๐˜ฎ๐˜ข๐˜ฎ๐˜ฎ๐˜ข๐˜ณ๐˜บ ๐˜จ๐˜ญ๐˜ข๐˜ฏ๐˜ฅ" Image
2) Reference


Avian influenza A virus (IAV) infections were recently detected in dairy cows in the US. Cattle are not typically considered susceptible hosts for IAV. biorxiv.org/content/10.110โ€ฆ
Image
3) IAV receptors are sialic acids linked to galactose in either an ฮฑ2,3 or ฮฑ2,6 linkage. Human IAVs prefer the ฮฑ2,6 receptor, avian IAVs the ฮฑ2,3 receptor.
The study investigated expression of IAV receptors (ฮฑ2,3, ฮฑ2,6, ฮฑ2,3-ฮฒ1,4, ฮฑ2,3-ฮฒ1,3) in bovine respiratory tract ...
Read 7 tweets
May 4
๐—›5๐—ก1 ๐—Ÿ๐—”๐—ฆ๐—ง ๐—จ๐—ฃ๐——๐—”๐—ง๐—˜ !
(๐Ÿงต ๐˜—๐˜ˆ๐˜™๐˜› 3 : ๐˜›๐˜ฉ๐˜ฆ ๐˜™๐˜๐˜š๐˜’๐˜š)

"H5N1 SCENARIO-based Human Health Risk Assessment for the United States as of [5/1/2024]" Image
2) The risk assessment report considers 5 possible SCENARIOS for how the H5N1 outbreak in cattle could evolve and the corresponding risks to human health.
Currently the outbreak is judged to be between SCENARIOS 2 and 3, with widespread cases in cattle and some spread to ... Image
3) ...other animals like cats, but no human-to-human transmission reported so far.
SCENARIO 1 assumes minimal spread in animals and low risk to all human populations.

SCENARIO 2 involves widespread cattle spread and some cow-to-human transmission ... Image
Read 7 tweets
May 4
๐—›5๐—ก1 ๐—Ÿ๐—”๐—ฆ๐—ง ๐—จ๐—ฃ๐——๐—”๐—ง๐—˜ !
(๐Ÿงต ๐˜—๐˜ˆ๐˜™๐˜› 2)
"๐˜—๐˜ณ๐˜ฆ๐˜ญ๐˜ช๐˜ฎ๐˜ช๐˜ฏ๐˜ข๐˜ณ๐˜บ ๐˜ณ๐˜ฆ๐˜ฑ๐˜ฐ๐˜ณ๐˜ต ๐˜ฐ๐˜ฏ ๐˜จ๐˜ฆ๐˜ฏ๐˜ฐ๐˜ฎ๐˜ช๐˜ค ๐˜ฆ๐˜ฑ๐˜ช๐˜ฅ๐˜ฆ๐˜ฎ๐˜ช๐˜ฐ๐˜ญ๐˜ฐ๐˜จ๐˜บ ๐˜ฐ๐˜ง ๐˜ต๐˜ฉ๐˜ฆ 2024 ๐˜5๐˜•1 ๐˜ช๐˜ฏ๐˜ง๐˜ญ๐˜ถ๐˜ฆ๐˜ฏ๐˜ป๐˜ข ๐˜ˆ ๐˜ท๐˜ช๐˜ณ๐˜ถ๐˜ด ๐˜ฐ๐˜ถ๐˜ต๐˜ฃ๐˜ณ๐˜ฆ๐˜ข๐˜ฌ ๐˜ช๐˜ฏ ๐˜œ.๐˜š. ๐˜ค๐˜ข๐˜ต๐˜ต๐˜ญ๐˜ฆ (๐˜ฑ๐˜ข๐˜ณ๐˜ต 2)"
virological.org/t/preliminary-โ€ฆ
Image
2) The original cattle H5N1 virus's hemagglutinin (HA) protein was not adapted to bind to human-like receptors. The closest-related sequences to the cattle H5N1 HA came from wild birds, indicating no pre-adaptation to mammalian receptors. Image
3) Mutations in HA and the polymerase have been observed in small clades from cattle and cats, but their significance is unclear. Without changes in HA affecting receptor binding, the risk of human transmission is low.
H5N1 has transmitted from cattle to wild birds, poultry ...
Read 7 tweets
May 4
๐—›5๐—ก1 ๐—Ÿ๐—”๐—ฆ๐—ง ๐—จ๐—ฃ๐——๐—”๐—ง๐—˜ !
(๐Ÿงต ๐˜—๐˜ˆ๐˜™๐˜› 1)
"๐˜—๐˜ณ๐˜ฆ๐˜ญ๐˜ช๐˜ฎ๐˜ช๐˜ฏ๐˜ข๐˜ณ๐˜บ ๐˜ณ๐˜ฆ๐˜ฑ๐˜ฐ๐˜ณ๐˜ต ๐˜ฐ๐˜ฏ ๐˜จ๐˜ฆ๐˜ฏ๐˜ฐ๐˜ฎ๐˜ช๐˜ค ๐˜ฆ๐˜ฑ๐˜ช๐˜ฅ๐˜ฆ๐˜ฎ๐˜ช๐˜ฐ๐˜ญ๐˜ฐ๐˜จ๐˜บ ๐˜ฐ๐˜ง ๐˜ต๐˜ฉ๐˜ฆ 2024 ๐˜5๐˜•1 ๐˜ช๐˜ฏ๐˜ง๐˜ญ๐˜ถ๐˜ฆ๐˜ฏ๐˜ป๐˜ข ๐˜ˆ ๐˜ท๐˜ช๐˜ณ๐˜ถ๐˜ด ๐˜ฐ๐˜ถ๐˜ต๐˜ฃ๐˜ณ๐˜ฆ๐˜ข๐˜ฌ ๐˜ช๐˜ฏ ๐˜œ.๐˜š. ๐˜ค๐˜ข๐˜ต๐˜ต๐˜ญ๐˜ฆ (๐˜ฑ๐˜ข๐˜ณ๐˜ต 1)" Image
2) H/t @MichaelWorobey @PeacockFlu and colleagues



BACKGROUND :
Reassortment of the virus with local avian strains has generated diverse genotypes. virological.org/t/preliminary-โ€ฆ
Image
3) The virus has a high propensity to infect mammals, including domestic cats, foxes, mink, and pinnipeds. Mammalian infections lead to severe disease and quick adaptation. Bird-to-mammal transmission is uncertain. Image
Read 10 tweets
May 4
๐—”๐˜๐—บ๐—ผ๐˜€๐—ฝ๐—ต๐—ฒ๐—ฟ๐—ฒ ๐—ฝ๐—ฎ๐—ฟ๐˜๐—ถ๐—ฐ๐˜‚๐—น๐—ฎ๐˜๐—ฒ ๐—บ๐—ฎ๐˜๐˜๐—ฒ๐—ฟ ๐—ฎ๐—ป๐—ฑ ๐—ฟ๐—ฒ๐˜€๐—ฝ๐—ถ๐—ฟ๐—ฎ๐˜๐—ผ๐—ฟ๐˜† ๐—ฑ๐—ถ๐˜€๐—ฒ๐—ฎ๐˜€๐—ฒ๐˜€ ๐—ฑ๐˜‚๐—ฟ๐—ถ๐—ป๐—ด ๐—–๐—ข๐—ฉ๐—œ๐——-19 ๐—ถ๐—ป ๐—ž๐—ผ๐—ฟ๐—ฒ๐—ฎ

nature.com/articles/s4159โ€ฆ
Image
2) The study analyzed the relationship between particulate matter (PM10 and PM2.5) levels and hospital admissions for respiratory and non-respiratory diseases in major cities in South Korea from 2016-2020. Image
3) It compared the relationships before the COVID-19 pandemic (2016-2019) to during the pandemic in 2020, when non-pharmaceutical interventions (NPIs) like social distancing and mask-wearing were implemented. Image
Read 8 tweets
May 4
๐—” ๐˜€๐—ต๐—ผ๐—ฟ๐˜ ๐˜๐—ฟ๐—ถ๐—ฝ ๐˜„๐—ถ๐˜๐—ต ๐—ฆ๐—”๐—ฅ๐—ฆ-๐—–๐—ผ๐—ฉ-2 ๐—ผ๐—ป ๐˜๐—ต๐—ฒ ๐˜‚๐—ฝ๐—ฝ๐—ฒ๐—ฟ ๐—ฑ๐—ฒ๐—ฐ๐—ธ ๐—ผ๐—ณ ๐—ฎ ๐—ฝ๐—ฎ๐˜€๐˜€๐—ฒ๐—ป๐—ด๐—ฒ๐—ฟ ๐˜€๐—ต๐—ถ๐—ฝ !

๐˜ˆ ๐˜ท๐˜ฆ๐˜ณ๐˜บ ๐˜ช๐˜ฏ๐˜ต๐˜ฆ๐˜ณ๐˜ฆ๐˜ด๐˜ต๐˜ช๐˜ฏ๐˜จ ๐˜ด๐˜ต๐˜ถ๐˜ฅ๐˜บ ๐˜ข๐˜ฃ๐˜ฐ๐˜ถ๐˜ต ๐˜ฅ๐˜ณ๐˜ฐ๐˜ฑ๐˜ญ๐˜ฆ๐˜ต๐˜ด ๐Ÿ‘ @0bj3ctivity ๐Ÿ˜‚
cell.com/heliyon/fullteโ€ฆ

Image
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2) The study developed a numerical model to simulate the transmission of SARS-CoV-2 virus through droplets expelled during coughing and sneezing on the upper deck of a passenger ship. Image
3) Computational fluid dynamics (CFD) was used to model the airflow and determine the contamination zone from respiratory droplets. Parameters like voyage duration, passenger numbers, social distancing, mask wearing were investigated. Image
Read 7 tweets

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